MXPA04000531A - Acilsemicarbazidas como inhibidores de cinasa dependiente de ciclina utiles como agentes anti-cancer y anti-proliferativos. - Google Patents
Acilsemicarbazidas como inhibidores de cinasa dependiente de ciclina utiles como agentes anti-cancer y anti-proliferativos.Info
- Publication number
- MXPA04000531A MXPA04000531A MXPA04000531A MXPA04000531A MXPA04000531A MX PA04000531 A MXPA04000531 A MX PA04000531A MX PA04000531 A MXPA04000531 A MX PA04000531A MX PA04000531 A MXPA04000531 A MX PA04000531A MX PA04000531 A MXPA04000531 A MX PA04000531A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- cyclin dependent
- acylsemicarbazides
- proliferative agents
- kinase inhibitors
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 title abstract 2
- 230000001028 anti-proliverative effect Effects 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 239000002875 cyclin dependent kinase inhibitor Substances 0.000 title 1
- 229940043378 cyclin-dependent kinase inhibitor Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000002062 proliferating effect Effects 0.000 abstract 2
- GHFDYLOGYDGRHI-UHFFFAOYSA-N 1h-indeno[1,2-c]pyrazol-4-one Chemical class C12=CC=CC=C2C(=O)C2=C1NN=C2 GHFDYLOGYDGRHI-UHFFFAOYSA-N 0.000 abstract 1
- 108091007914 CDKs Proteins 0.000 abstract 1
- 102000016736 Cyclin Human genes 0.000 abstract 1
- 108050006400 Cyclin Proteins 0.000 abstract 1
- 102000003903 Cyclin-dependent kinases Human genes 0.000 abstract 1
- 108090000266 Cyclin-dependent kinases Proteins 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/906,963 US6593356B2 (en) | 1999-10-20 | 2001-07-16 | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
| PCT/US2002/022663 WO2003007883A2 (en) | 2001-07-16 | 2002-07-16 | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04000531A true MXPA04000531A (es) | 2004-05-04 |
Family
ID=25423309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04000531A MXPA04000531A (es) | 2001-07-16 | 2002-07-16 | Acilsemicarbazidas como inhibidores de cinasa dependiente de ciclina utiles como agentes anti-cancer y anti-proliferativos. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6593356B2 (enExample) |
| EP (1) | EP1417177A4 (enExample) |
| JP (1) | JP2004536853A (enExample) |
| KR (1) | KR20040015368A (enExample) |
| CN (1) | CN1553900A (enExample) |
| BR (1) | BR0211203A (enExample) |
| CA (1) | CA2453594A1 (enExample) |
| HU (1) | HUP0401588A3 (enExample) |
| IL (1) | IL159863A0 (enExample) |
| MX (1) | MXPA04000531A (enExample) |
| NO (1) | NO20040175L (enExample) |
| PL (1) | PL366912A1 (enExample) |
| RU (1) | RU2004104329A (enExample) |
| WO (1) | WO2003007883A2 (enExample) |
| ZA (1) | ZA200400332B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040048844A1 (en) * | 1999-10-20 | 2004-03-11 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
| JP3821090B2 (ja) * | 2002-10-22 | 2006-09-13 | トヨタ自動車株式会社 | 内燃機関の始動制御装置 |
| US7456169B2 (en) | 2003-02-27 | 2008-11-25 | Abbott Laboratories Inc. | Heterocyclic kinase inhibitors |
| US7320986B2 (en) | 2003-03-07 | 2008-01-22 | Abbott Labortories | Fused tri and tetra-cyclic pyrazole kinase inhibitors |
| ES2551293T3 (es) | 2004-03-24 | 2015-11-17 | Abbvie Inc. | Inhibidores de quinasas de pirazol tricíclicos |
| US8512243B2 (en) | 2005-09-30 | 2013-08-20 | Abbott Diabetes Care Inc. | Integrated introducer and transmitter assembly and methods of use |
| US8029441B2 (en) | 2006-02-28 | 2011-10-04 | Abbott Diabetes Care Inc. | Analyte sensor transmitter unit configuration for a data monitoring and management system |
| US20100198034A1 (en) | 2009-02-03 | 2010-08-05 | Abbott Diabetes Care Inc. | Compact On-Body Physiological Monitoring Devices and Methods Thereof |
| EP3001194B1 (en) | 2009-08-31 | 2019-04-17 | Abbott Diabetes Care, Inc. | Medical devices and methods |
| WO2011162843A1 (en) | 2010-03-24 | 2011-12-29 | Abbott Diabetes Care Inc. | Medical device inserters and processes of inserting and using medical devices |
| LT4056105T (lt) | 2011-12-11 | 2024-01-10 | Abbott Diabetes Care, Inc. | Analitės jutiklių įrenginiai |
| US10213139B2 (en) | 2015-05-14 | 2019-02-26 | Abbott Diabetes Care Inc. | Systems, devices, and methods for assembling an applicator and sensor control device |
| EP3377908B1 (en) | 2015-11-18 | 2020-08-05 | Genzyme Corporation | Biomarker of polycystic kidney disease and uses thereof |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| USD1002852S1 (en) | 2019-06-06 | 2023-10-24 | Abbott Diabetes Care Inc. | Analyte sensor device |
| CN114641466B (zh) | 2019-06-12 | 2025-09-30 | 诺瑟拉有限公司 | 磺酰脲衍生物及其用途 |
| USD999913S1 (en) | 2020-12-21 | 2023-09-26 | Abbott Diabetes Care Inc | Analyte sensor inserter |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407103B2 (en) * | 1998-04-21 | 2002-06-18 | Bristol-Myers Squibb Pharma Company | Indeno [1,2-c] pyrazol-4-ones and their uses |
| DE69940951D1 (de) * | 1998-04-21 | 2009-07-16 | Bristol Myers Squibb Pharma Co | Nd wachstumshemmende mittel |
| US6291504B1 (en) * | 1999-10-20 | 2001-09-18 | Dupont Pharmaceuticals Company | Acylsemicarbazides and their uses |
| JP2004524277A (ja) * | 2000-10-20 | 2004-08-12 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | アシルセミカルバジド及びサイクリン依存性キナーゼ（ｃｄｋ）阻害剤としてのその使用 |
| US6706718B2 (en) * | 2000-12-01 | 2004-03-16 | Bristol-Myers Squibb Company | 3-(2,4-dimethylthiazol-5-yl)indeno[1,2-c]pyrazol-4-one derivatives and their uses |
-
2001
- 2001-07-16 US US09/906,963 patent/US6593356B2/en not_active Expired - Lifetime
-
2002
- 2002-07-16 CA CA002453594A patent/CA2453594A1/en not_active Abandoned
- 2002-07-16 RU RU2004104329/04A patent/RU2004104329A/ru not_active Application Discontinuation
- 2002-07-16 BR BR0211203-5A patent/BR0211203A/pt not_active IP Right Cessation
- 2002-07-16 CN CNA028177614A patent/CN1553900A/zh active Pending
- 2002-07-16 WO PCT/US2002/022663 patent/WO2003007883A2/en not_active Ceased
- 2002-07-16 KR KR10-2004-7000762A patent/KR20040015368A/ko not_active Withdrawn
- 2002-07-16 IL IL15986302A patent/IL159863A0/xx unknown
- 2002-07-16 EP EP02748186A patent/EP1417177A4/en not_active Withdrawn
- 2002-07-16 MX MXPA04000531A patent/MXPA04000531A/es unknown
- 2002-07-16 JP JP2003513492A patent/JP2004536853A/ja not_active Abandoned
- 2002-07-16 PL PL02366912A patent/PL366912A1/xx not_active Application Discontinuation
- 2002-07-16 HU HU0401588A patent/HUP0401588A3/hu unknown
-
2004
- 2004-01-15 ZA ZA2004/00332A patent/ZA200400332B/en unknown
- 2004-01-15 NO NO20040175A patent/NO20040175L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1417177A4 (en) | 2005-10-19 |
| US20030073686A1 (en) | 2003-04-17 |
| WO2003007883A3 (en) | 2003-05-22 |
| US6593356B2 (en) | 2003-07-15 |
| HUP0401588A3 (en) | 2005-06-28 |
| JP2004536853A (ja) | 2004-12-09 |
| PL366912A1 (en) | 2005-02-07 |
| NO20040175L (no) | 2004-03-12 |
| CN1553900A (zh) | 2004-12-08 |
| KR20040015368A (ko) | 2004-02-18 |
| WO2003007883A2 (en) | 2003-01-30 |
| ZA200400332B (en) | 2005-06-29 |
| CA2453594A1 (en) | 2003-01-30 |
| RU2004104329A (ru) | 2005-07-10 |
| IL159863A0 (en) | 2004-06-20 |
| HUP0401588A2 (hu) | 2005-01-28 |
| BR0211203A (pt) | 2004-09-28 |
| EP1417177A2 (en) | 2004-05-12 |
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