IL159863A0 - Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents - Google Patents

Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents

Info

Publication number
IL159863A0
IL159863A0 IL15986302A IL15986302A IL159863A0 IL 159863 A0 IL159863 A0 IL 159863A0 IL 15986302 A IL15986302 A IL 15986302A IL 15986302 A IL15986302 A IL 15986302A IL 159863 A0 IL159863 A0 IL 159863A0
Authority
IL
Israel
Prior art keywords
acylsemicarbazides
cancer
kinase inhibitors
dependent kinase
cyclin dependent
Prior art date
Application number
IL15986302A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of IL159863A0 publication Critical patent/IL159863A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15986302A 2001-07-16 2002-07-16 Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents IL159863A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/906,963 US6593356B2 (en) 1999-10-20 2001-07-16 Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
PCT/US2002/022663 WO2003007883A2 (en) 2001-07-16 2002-07-16 Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents

Publications (1)

Publication Number Publication Date
IL159863A0 true IL159863A0 (en) 2004-06-20

Family

ID=25423309

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15986302A IL159863A0 (en) 2001-07-16 2002-07-16 Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents

Country Status (15)

Country Link
US (1) US6593356B2 (xx)
EP (1) EP1417177A4 (xx)
JP (1) JP2004536853A (xx)
KR (1) KR20040015368A (xx)
CN (1) CN1553900A (xx)
BR (1) BR0211203A (xx)
CA (1) CA2453594A1 (xx)
HU (1) HUP0401588A3 (xx)
IL (1) IL159863A0 (xx)
MX (1) MXPA04000531A (xx)
NO (1) NO20040175L (xx)
PL (1) PL366912A1 (xx)
RU (1) RU2004104329A (xx)
WO (1) WO2003007883A2 (xx)
ZA (1) ZA200400332B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040048844A1 (en) * 1999-10-20 2004-03-11 Bristol-Myers Squibb Pharma Company Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
JP3821090B2 (ja) * 2002-10-22 2006-09-13 トヨタ自動車株式会社 内燃機関の始動制御装置
US7456169B2 (en) 2003-02-27 2008-11-25 Abbott Laboratories Inc. Heterocyclic kinase inhibitors
US7320986B2 (en) 2003-03-07 2008-01-22 Abbott Labortories Fused tri and tetra-cyclic pyrazole kinase inhibitors
EP1740579B1 (en) 2004-03-24 2015-08-19 AbbVie Inc. Tricyclic pyrazole kinase inhibitors
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US20100198034A1 (en) 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
CN105686807B (zh) 2009-08-31 2019-11-15 雅培糖尿病护理公司 医疗设备
EP2552532A1 (en) 2010-03-24 2013-02-06 Abbott Diabetes Care, Inc. Medical device inserters and processes of inserting and using medical devices
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
JP6895963B2 (ja) 2015-11-18 2021-06-30 ジェンザイム・コーポレーション 多発性嚢胞腎のバイオマーカーおよびその使用
GB201721185D0 (en) 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407103B2 (en) * 1998-04-21 2002-06-18 Bristol-Myers Squibb Pharma Company Indeno [1,2-c] pyrazol-4-ones and their uses
CN1297442A (zh) * 1998-04-21 2001-05-30 杜邦药品公司 用作抗癌剂和抗增殖剂的5-氨基茚并[1,2-c]吡唑-4-酮类化合物
US6291504B1 (en) * 1999-10-20 2001-09-18 Dupont Pharmaceuticals Company Acylsemicarbazides and their uses
JP2004524277A (ja) * 2000-10-20 2004-08-12 ブリストル−マイヤーズ スクイブ ファーマ カンパニー アシルセミカルバジド及びサイクリン依存性キナーゼ(cdk)阻害剤としてのその使用
US6706718B2 (en) * 2000-12-01 2004-03-16 Bristol-Myers Squibb Company 3-(2,4-dimethylthiazol-5-yl)indeno[1,2-c]pyrazol-4-one derivatives and their uses

Also Published As

Publication number Publication date
WO2003007883A2 (en) 2003-01-30
HUP0401588A3 (en) 2005-06-28
KR20040015368A (ko) 2004-02-18
PL366912A1 (en) 2005-02-07
US6593356B2 (en) 2003-07-15
CA2453594A1 (en) 2003-01-30
ZA200400332B (en) 2005-06-29
JP2004536853A (ja) 2004-12-09
NO20040175L (no) 2004-03-12
EP1417177A2 (en) 2004-05-12
US20030073686A1 (en) 2003-04-17
EP1417177A4 (en) 2005-10-19
RU2004104329A (ru) 2005-07-10
HUP0401588A2 (hu) 2005-01-28
MXPA04000531A (es) 2004-05-04
BR0211203A (pt) 2004-09-28
WO2003007883A3 (en) 2003-05-22
CN1553900A (zh) 2004-12-08

Similar Documents

Publication Publication Date Title
IL158985A0 (en) Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents
AU2002362895A1 (en) 5-carbamoyl-1,1-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
MXPA03006420A (es) Diaminotiazoles.
HK1066546A1 (en) Trifluoromethylpurines as phosphodiesterase 4 inhibitors
AU2002346929A1 (en) 5-acylamino-1,1-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
PL378368A1 (pl) Kompozycje i sposoby wykorzystywane w skojarzonej terapii przeciwwirusowej
IL161516A0 (en) Benzimidazoles useful as protein kinase inhibitors
AU2002357119A8 (en) Mitocidal compositions and methods
PL366038A1 (en) Nucleoside compounds and uses thereof
EP1423120A4 (en) 2H-PHTALAZINE-1-ONES AND METHODS OF USE THEREOF
HK1061854A1 (en) Spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
PL372620A1 (en) New pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors
PL363391A1 (en) Phthalayinone-piperidino-derivatives as pde4 inhibitors
IL159863A0 (en) Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
EP1469860A4 (en) ANTICANCER COMBINATION AND USE THEREOF
AU2002357748A8 (en) Osteopontin-related compositions and methods
GB2376928B (en) Personal hoverplane having four tiltmotors
GB0101686D0 (en) Cyclin dependent kinase inhibitors
EP1583528A4 (en) NF-KB INHIBITORS AND ITS USES
EP1631145A4 (en) P38 KINASEHEMMER COMPOSITION AND METHOD FOR THEIR USE
EP1507542A4 (en) ANTICANCER PREPARATION
AU2002359869A8 (en) Pak5-related compositions and methods
GB0230292D0 (en) Anti-cancer agents
GB2369445B (en) Component measures
AU2002332460A1 (en) Pyrazole-derived kinase inhibitors and uses thereof