MXPA03007885A - Norbuprenorfina n-but-3-enilo y metodos de uso. - Google Patents

Norbuprenorfina n-but-3-enilo y metodos de uso.

Info

Publication number
MXPA03007885A
MXPA03007885A MXPA03007885A MXPA03007885A MXPA03007885A MX PA03007885 A MXPA03007885 A MX PA03007885A MX PA03007885 A MXPA03007885 A MX PA03007885A MX PA03007885 A MXPA03007885 A MX PA03007885A MX PA03007885 A MXPA03007885 A MX PA03007885A
Authority
MX
Mexico
Prior art keywords
treating
norbuprenorphine
enyl
analgesic
compound
Prior art date
Application number
MXPA03007885A
Other languages
English (en)
Inventor
E Reidenberg Bruce
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of MXPA03007885A publication Critical patent/MXPA03007885A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion proporciona un compuesto que tiene la estructura: y sales farmaceuticamente aceptables del mismo, asi como composiciones que incluyen tales compuestos. La presente invencion tambien proporciona metodos para (1) prevenir el dolor, (2) tratar el dolor, (3) inducir la sedacion, (4) tratar la adiccion a opiato, (5) tratar el retraimiento a opiato (sindrome de abstinencia) y/o (6) tratar la tos en un paciente que necesita de los mismos, administrando un compuesto o composicion de la presente invencion.
MXPA03007885A 2001-03-02 2002-03-04 Norbuprenorfina n-but-3-enilo y metodos de uso. MXPA03007885A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27281901P 2001-03-02 2001-03-02
PCT/US2002/006766 WO2002070524A2 (en) 2001-03-02 2002-03-04 N-but-3-enyl norbuprenorphine and its use as analgesic

Publications (1)

Publication Number Publication Date
MXPA03007885A true MXPA03007885A (es) 2004-05-24

Family

ID=23041438

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03007885A MXPA03007885A (es) 2001-03-02 2002-03-04 Norbuprenorfina n-but-3-enilo y metodos de uso.

Country Status (14)

Country Link
US (2) US7125884B2 (es)
EP (1) EP1368356A2 (es)
JP (1) JP2004538256A (es)
KR (1) KR20030088445A (es)
CN (1) CN1507448A (es)
BR (1) BR0207978A (es)
CA (1) CA2439859A1 (es)
IL (1) IL157662A0 (es)
MX (1) MXPA03007885A (es)
NO (1) NO20033854L (es)
NZ (1) NZ528241A (es)
RU (1) RU2003129531A (es)
WO (1) WO2002070524A2 (es)
ZA (1) ZA200307337B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
DE10340428B4 (de) * 2003-09-02 2015-02-12 Acino Ag Opioides Analgetikum enthaltende transdermale Formulierung
FR2875406B1 (fr) * 2004-09-21 2007-01-05 Danisco Souche de lactobacillus acidophilus ayant des proprietes analgesiques au niveau du systeme gastro-intestinal
DE102006046745A1 (de) * 2006-09-29 2008-04-03 Grünenthal GmbH Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz
US8530494B2 (en) * 2008-07-30 2013-09-10 Purdue Pharma Lp Buprenophine analogs
JP5977240B2 (ja) 2010-09-21 2016-08-24 パーデュー、ファーマ、リミテッド、パートナーシップ ブプレノルフィン類似体
WO2013084060A1 (en) * 2011-12-08 2013-06-13 Purdue Pharma L.P. Quaternized buprenorphine analogs
RU2503678C1 (ru) * 2012-08-21 2014-01-10 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) 7α-(1-ГИДРОКСИ-2,2,2-ТРИФТОРЭТИЛ)-17-МЕТИЛ-3,6-ДИМЕТОКСИ-4,5α-ЭПОКСИ-6α,14αЭТЕНОИЗОМОРФИНАН И СПОСОБ ЕГО ПОЛУЧЕНИЯ
RU2506265C1 (ru) * 2012-08-21 2014-02-10 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) Фторсодержащие производные тевинола и орвинола и способы их получения (варианты)
TW201431842A (zh) 2012-11-09 2014-08-16 Purdue Pharma Lp 苯並嗎啡烷類似物及其應用
WO2014087226A1 (en) 2012-12-07 2014-06-12 Purdue Pharma L.P. Buprenorphine analogs as opiod receptor modulators
ES2653265T3 (es) * 2012-12-28 2018-02-06 Purdue Pharma Lp Morfinanos sustituidos y el uso de éstos
JP6182620B2 (ja) 2013-01-31 2017-08-16 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用
US8969358B2 (en) 2013-03-15 2015-03-03 Purdue Pharma L.P. Buprenorphine analogs
AU2014370062A1 (en) 2013-12-26 2016-08-11 Purdue Pharma L.P. Ring-contracted morphinans and the use thereof
WO2015097547A1 (en) 2013-12-26 2015-07-02 Purdue Pharma L.P. 10-substituted morphinan hydantoins
US9862726B2 (en) 2013-12-26 2018-01-09 Purdue Pharma L.P. Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans
WO2015097548A1 (en) 2013-12-26 2015-07-02 Purdue Pharma L.P. 7-beta-alkyl analogs of orvinols
WO2015099863A1 (en) 2013-12-27 2015-07-02 Purdue Pharma L.P. 6-substituted and 7-substituted morphinan analogs and the use thereof
JP2017521373A (ja) 2014-05-27 2017-08-03 パーデュー、ファーマ、リミテッド、パートナーシップ スピロ環モルフィナン及びその使用
EP3154972A4 (en) 2014-06-13 2017-11-22 Purdue Pharma L.P. Azamophinan derivatives and use thereof
MA41125A (fr) 2014-12-05 2017-10-10 Purdue Pharma Lp Dérivés de 6.7-cyclomorphinane et leur utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474101A (en) * 1960-09-05 1969-10-21 Reckitt & Sons Ltd Thebaine and oripavine derivatives
US3285914A (en) * 1964-06-11 1966-11-15 Smith Kline French Lab 3-n-substituted derivatives of oripavine and thebaine
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
ATE314372T1 (de) 1998-01-29 2006-01-15 Univ Monash Therapeutische verbindungen

Also Published As

Publication number Publication date
RU2003129531A (ru) 2005-04-10
WO2002070524A3 (en) 2002-10-17
US20040087605A1 (en) 2004-05-06
ZA200307337B (en) 2004-12-20
KR20030088445A (ko) 2003-11-19
CA2439859A1 (en) 2002-09-12
US7125884B2 (en) 2006-10-24
IL157662A0 (en) 2004-03-28
US20050192308A1 (en) 2005-09-01
NO20033854D0 (no) 2003-09-01
CN1507448A (zh) 2004-06-23
JP2004538256A (ja) 2004-12-24
BR0207978A (pt) 2004-03-02
NO20033854L (no) 2003-10-28
EP1368356A2 (en) 2003-12-10
WO2002070524A2 (en) 2002-09-12
NZ528241A (en) 2004-08-27

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