MXPA03001196A - Un nuevo miembro de la familia del gen de oxidasa de lisilo. - Google Patents

Un nuevo miembro de la familia del gen de oxidasa de lisilo.

Info

Publication number
MXPA03001196A
MXPA03001196A MXPA03001196A MXPA03001196A MXPA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A
Authority
MX
Mexico
Prior art keywords
lysyl oxidase
gene family
oxidase gene
novel member
protein
Prior art date
Application number
MXPA03001196A
Other languages
English (en)
Inventor
Eric Beer
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA03001196A publication Critical patent/MXPA03001196A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se refiere a nuevos genes de oxidasa de lisilo, denominados EER-7. La invencion se refiere a la proteina y acidos nucleicos que codifican la proteina. La invencion se refiere ademas a un sistema de ensayo para identificar compuestos que modulan selectivamente la actividad de la proteina EER-7 mediante la interaccion con receptores de estrogeno.
MXPA03001196A 2000-08-08 2001-08-08 Un nuevo miembro de la familia del gen de oxidasa de lisilo. MXPA03001196A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22376300P 2000-08-08 2000-08-08
US25583800P 2000-12-15 2000-12-15
PCT/US2001/024942 WO2002012470A2 (en) 2000-08-08 2001-08-08 A member of the lysyl oxidase gene family

Publications (1)

Publication Number Publication Date
MXPA03001196A true MXPA03001196A (es) 2004-04-05

Family

ID=26918106

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03001196A MXPA03001196A (es) 2000-08-08 2001-08-08 Un nuevo miembro de la familia del gen de oxidasa de lisilo.

Country Status (12)

Country Link
US (2) US7208300B2 (es)
EP (1) EP1354046B1 (es)
JP (1) JP2004505631A (es)
AT (1) ATE364087T1 (es)
AU (1) AU2001284769A1 (es)
BR (1) BR0113257A (es)
CA (1) CA2418952A1 (es)
DE (1) DE60128830T2 (es)
HK (1) HK1060148A1 (es)
IL (1) IL154036A0 (es)
MX (1) MXPA03001196A (es)
WO (1) WO2002012470A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
US8119599B2 (en) * 2001-08-31 2012-02-21 Orthopeutics, L.P. Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US20070021365A1 (en) * 2005-06-21 2007-01-25 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto
US9687262B2 (en) * 2005-11-30 2017-06-27 CARDINAL HEALTH SWITZERLAND 515 GmbH Methods and devices for treating vulnerable plaque
US10278947B2 (en) 2007-02-28 2019-05-07 Orthopeutics, L.P. Crosslinker enhanced repair of connective tissues
WO2009017833A2 (en) 2007-08-02 2009-02-05 Arresto Biosciences Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis
US9107935B2 (en) * 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
AU2010283997B2 (en) * 2009-08-21 2015-04-09 Gilead Biologics, Inc. Methods and compositions for treatment of pulmonary fibrotic disorders
MX2012002271A (es) * 2009-08-21 2012-07-20 Gilead Biologics Inc Metodos y composiciones terapeuticas.
EP2467714A4 (en) * 2009-08-21 2013-02-20 Gilead Biologics Inc IN VITRO SCREENING ASSAYS
US20110044907A1 (en) * 2009-08-21 2011-02-24 Derek Marshall In vivo screening assays
SG178845A1 (en) * 2009-08-21 2012-04-27 Gilead Biologics Inc Catalytic domains from lysyl oxidase and loxl2
CN103370080A (zh) 2010-02-04 2013-10-23 吉联亚生物科技有限公司 结合赖氨酰氧化酶样2（loxl2）的抗体和其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834213A (en) * 1991-05-02 1998-11-10 Baylor College Of Medicine Screening system and assay for identifying compounds that regulate steroid and orphan receptors mediation of DNA transcription
HUP0104719A3 (en) 1998-12-18 2004-03-01 Wyeth Corp Bioassay for identifying estrogen receptor-betha/alfa selective modulators
AU4073600A (en) 1999-04-09 2000-11-14 Human Genome Sciences, Inc. Bone morphogenic proteins
US7264926B2 (en) 2000-04-18 2007-09-04 Millennium Pharmaceuticals, Inc. Nucleoside Phosphatase
WO2001083702A2 (en) * 2000-05-03 2001-11-08 University Of Hawaii Novel members of the lysyl oxidases family of amine oxidases related applications
WO2001092495A2 (en) 2000-05-26 2001-12-06 Millennium Pharmaceuticals, Inc. A human lysyl ixodase (47765) and uses thereof

Also Published As

Publication number Publication date
ATE364087T1 (de) 2007-06-15
DE60128830T2 (de) 2008-01-31
BR0113257A (pt) 2003-10-28
EP1354046A2 (en) 2003-10-22
US7445920B2 (en) 2008-11-04
US20020102645A1 (en) 2002-08-01
US7208300B2 (en) 2007-04-24
IL154036A0 (en) 2003-07-31
DE60128830D1 (de) 2007-07-19
AU2001284769A1 (en) 2002-02-18
US20040171110A1 (en) 2004-09-02
HK1060148A1 (en) 2004-07-30
CA2418952A1 (en) 2002-02-14
EP1354046B1 (en) 2007-06-06
WO2002012470A2 (en) 2002-02-14
JP2004505631A (ja) 2004-02-26
WO2002012470A3 (en) 2003-08-28

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