MXPA03001196A - Un nuevo miembro de la familia del gen de oxidasa de lisilo. - Google Patents

Un nuevo miembro de la familia del gen de oxidasa de lisilo.

Info

Publication number
MXPA03001196A
MXPA03001196A MXPA03001196A MXPA03001196A MXPA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A MX PA03001196 A MXPA03001196 A MX PA03001196A
Authority
MX
Mexico
Prior art keywords
lysyl oxidase
gene family
oxidase gene
novel member
protein
Prior art date
Application number
MXPA03001196A
Other languages
English (en)
Inventor
Eric Beer
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA03001196A publication Critical patent/MXPA03001196A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

La presente invencion se refiere a nuevos genes de oxidasa de lisilo, denominados EER-7. La invencion se refiere a la proteina y acidos nucleicos que codifican la proteina. La invencion se refiere ademas a un sistema de ensayo para identificar compuestos que modulan selectivamente la actividad de la proteina EER-7 mediante la interaccion con receptores de estrogeno.
MXPA03001196A 2000-08-08 2001-08-08 Un nuevo miembro de la familia del gen de oxidasa de lisilo. MXPA03001196A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22376300P 2000-08-08 2000-08-08
US25583800P 2000-12-15 2000-12-15
PCT/US2001/024942 WO2002012470A2 (en) 2000-08-08 2001-08-08 A member of the lysyl oxidase gene family

Publications (1)

Publication Number Publication Date
MXPA03001196A true MXPA03001196A (es) 2004-04-05

Family

ID=26918106

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03001196A MXPA03001196A (es) 2000-08-08 2001-08-08 Un nuevo miembro de la familia del gen de oxidasa de lisilo.

Country Status (12)

Country Link
US (2) US7208300B2 (es)
EP (1) EP1354046B1 (es)
JP (1) JP2004505631A (es)
AT (1) ATE364087T1 (es)
AU (1) AU2001284769A1 (es)
BR (1) BR0113257A (es)
CA (1) CA2418952A1 (es)
DE (1) DE60128830T2 (es)
HK (1) HK1060148A1 (es)
IL (1) IL154036A0 (es)
MX (1) MXPA03001196A (es)
WO (1) WO2002012470A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
US8119599B2 (en) * 2001-08-31 2012-02-21 Orthopeutics, L.P. Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
US20070021365A1 (en) * 2005-06-21 2007-01-25 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US9687262B2 (en) * 2005-11-30 2017-06-27 CARDINAL HEALTH SWITZERLAND 515 GmbH Methods and devices for treating vulnerable plaque
US10278947B2 (en) 2007-02-28 2019-05-07 Orthopeutics, L.P. Crosslinker enhanced repair of connective tissues
JP5659014B2 (ja) 2007-08-02 2015-01-28 ジリード バイオロジクス，インク． 線維症、腫瘍浸潤、血管新生及び転移の治療及び診断のための方法及び組成物
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
WO2011022710A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc Therapeutic methods and compositions
US20110207144A1 (en) * 2009-08-21 2011-08-25 Derek Marshall In vitro screening assays
BR112012008054A2 (pt) 2009-08-21 2017-05-23 Gilead Biologics Inc domínios catalíticos de lisil oxidase e loxl2
WO2011022670A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vivo screening assays
KR20120054077A (ko) * 2009-08-21 2012-05-29 길리아드 바이오로직스, 인크. 폐 섬유증 장애의 치료를 위한 방법 및 조성물
RU2549684C2 (ru) 2010-02-04 2015-04-27 Джилид Байолоджикс, Инк. Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834213A (en) 1991-05-02 1998-11-10 Baylor College Of Medicine Screening system and assay for identifying compounds that regulate steroid and orphan receptors mediation of DNA transcription
HUP0104719A3 (en) 1998-12-18 2004-03-01 Wyeth Corp Bioassay for identifying estrogen receptor-betha/alfa selective modulators
WO2000061774A2 (en) 1999-04-09 2000-10-19 Human Genome Sciences, Inc. Bone morphogenic proteins
US20020068322A1 (en) * 2000-05-26 2002-06-06 Rachel Meyers 47765, a novel human lysyl oxidase and uses thereof
US7264926B2 (en) 2000-04-18 2007-09-04 Millennium Pharmaceuticals, Inc. Nucleoside Phosphatase
AU2001261194A1 (en) * 2000-05-03 2001-11-12 University Of Hawaii Novel members of the lysyl oxidases family of amine oxidases related applications

Also Published As

Publication number Publication date
CA2418952A1 (en) 2002-02-14
EP1354046A2 (en) 2003-10-22
DE60128830T2 (de) 2008-01-31
BR0113257A (pt) 2003-10-28
DE60128830D1 (de) 2007-07-19
HK1060148A1 (en) 2004-07-30
WO2002012470A3 (en) 2003-08-28
WO2002012470A2 (en) 2002-02-14
EP1354046B1 (en) 2007-06-06
US7208300B2 (en) 2007-04-24
JP2004505631A (ja) 2004-02-26
IL154036A0 (en) 2003-07-31
US20020102645A1 (en) 2002-08-01
US7445920B2 (en) 2008-11-04
AU2001284769A1 (en) 2002-02-18
US20040171110A1 (en) 2004-09-02
ATE364087T1 (de) 2007-06-15

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