AU2001284769A1 - A member of the lysyl oxidase gene family - Google Patents

A member of the lysyl oxidase gene family

Info

Publication number
AU2001284769A1
AU2001284769A1 AU2001284769A AU8476901A AU2001284769A1 AU 2001284769 A1 AU2001284769 A1 AU 2001284769A1 AU 2001284769 A AU2001284769 A AU 2001284769A AU 8476901 A AU8476901 A AU 8476901A AU 2001284769 A1 AU2001284769 A1 AU 2001284769A1
Authority
AU
Australia
Prior art keywords
lysyl oxidase
gene family
oxidase gene
protein
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284769A
Inventor
Ashok R. Bapat
Eric Beer
Ramesh A. Bhat
Mark J Evans
Elissa Ferris
Sotirios K. Karathanasis
Robert Mastroeni
Marshall S. Scicchitano
Jianziong Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2001284769A1 publication Critical patent/AU2001284769A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

The present invention relates to a novel lysyl oxidase genes, termed EER-7. The invention relates to the protein and nucleic acids encoding the protein. The invention further relates to an assay system to identify compounds that selectively modulate EER-7 protein activity by interaction with estrogen receptors.
AU2001284769A 2000-08-08 2001-08-08 A member of the lysyl oxidase gene family Abandoned AU2001284769A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22376300P 2000-08-08 2000-08-08
US60/223,763 2000-08-08
US25583800P 2000-12-15 2000-12-15
US60/255,838 2000-12-15
PCT/US2001/024942 WO2002012470A2 (en) 2000-08-08 2001-08-08 A member of the lysyl oxidase gene family

Publications (1)

Publication Number Publication Date
AU2001284769A1 true AU2001284769A1 (en) 2002-02-18

Family

ID=26918106

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284769A Abandoned AU2001284769A1 (en) 2000-08-08 2001-08-08 A member of the lysyl oxidase gene family

Country Status (12)

Country Link
US (2) US7208300B2 (en)
EP (1) EP1354046B1 (en)
JP (1) JP2004505631A (en)
AT (1) ATE364087T1 (en)
AU (1) AU2001284769A1 (en)
BR (1) BR0113257A (en)
CA (1) CA2418952A1 (en)
DE (1) DE60128830T2 (en)
HK (1) HK1060148A1 (en)
IL (1) IL154036A0 (en)
MX (1) MXPA03001196A (en)
WO (1) WO2002012470A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
US8119599B2 (en) * 2001-08-31 2012-02-21 Orthopeutics, L.P. Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
US20070021365A1 (en) * 2005-06-21 2007-01-25 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US9687262B2 (en) * 2005-11-30 2017-06-27 CARDINAL HEALTH SWITZERLAND 515 GmbH Methods and devices for treating vulnerable plaque
US10278947B2 (en) 2007-02-28 2019-05-07 Orthopeutics, L.P. Crosslinker enhanced repair of connective tissues
JP5312459B2 (en) 2007-08-02 2013-10-09 ジリード バイオロジクス，インク． LOX and LOXL2 inhibitors and uses thereof
US9107935B2 (en) * 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
AU2010284036B2 (en) 2009-08-21 2014-12-18 Gilead Biologics, Inc. Catalytic domains from lysyl oxidase and LOXL2
AU2010284000A1 (en) * 2009-08-21 2012-03-22 Gilead Biologics, Inc. In vitro screening assays
WO2011022670A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vivo screening assays
RU2561672C2 (en) * 2009-08-21 2015-08-27 Джилид Байолоджикс, Инк. Methods and compositions for treatment of pulmonary fibrous diseases
RU2012110587A (en) * 2009-08-21 2013-09-27 Джилид Байолоджикс, Инк. THERAPEUTIC METHODS AND COMPOSITIONS
SG183174A1 (en) 2010-02-04 2012-09-27 Gilead Biologics Inc Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834213A (en) 1991-05-02 1998-11-10 Baylor College Of Medicine Screening system and assay for identifying compounds that regulate steroid and orphan receptors mediation of DNA transcription
HUP0104719A3 (en) * 1998-12-18 2004-03-01 Wyeth Corp Bioassay for identifying estrogen receptor-betha/alfa selective modulators
AU4073600A (en) 1999-04-09 2000-11-14 Human Genome Sciences, Inc. Bone morphogenic proteins
US20020068322A1 (en) * 2000-05-26 2002-06-06 Rachel Meyers 47765, a novel human lysyl oxidase and uses thereof
US7264926B2 (en) * 2000-04-18 2007-09-04 Millennium Pharmaceuticals, Inc. Nucleoside Phosphatase
WO2001083702A2 (en) * 2000-05-03 2001-11-08 University Of Hawaii Novel members of the lysyl oxidases family of amine oxidases related applications

Also Published As

Publication number Publication date
DE60128830D1 (en) 2007-07-19
CA2418952A1 (en) 2002-02-14
BR0113257A (en) 2003-10-28
US20020102645A1 (en) 2002-08-01
US7208300B2 (en) 2007-04-24
HK1060148A1 (en) 2004-07-30
DE60128830T2 (en) 2008-01-31
EP1354046A2 (en) 2003-10-22
EP1354046B1 (en) 2007-06-06
US7445920B2 (en) 2008-11-04
WO2002012470A2 (en) 2002-02-14
ATE364087T1 (en) 2007-06-15
MXPA03001196A (en) 2004-04-05
JP2004505631A (en) 2004-02-26
US20040171110A1 (en) 2004-09-02
WO2002012470A3 (en) 2003-08-28
IL154036A0 (en) 2003-07-31

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