AU2001261194A1 - Novel members of the lysyl oxidases family of amine oxidases related applications - Google Patents

Novel members of the lysyl oxidases family of amine oxidases related applications

Info

Publication number
AU2001261194A1
AU2001261194A1 AU2001261194A AU6119401A AU2001261194A1 AU 2001261194 A1 AU2001261194 A1 AU 2001261194A1 AU 2001261194 A AU2001261194 A AU 2001261194A AU 6119401 A AU6119401 A AU 6119401A AU 2001261194 A1 AU2001261194 A1 AU 2001261194A1
Authority
AU
Australia
Prior art keywords
oxidases
related applications
family
lysyl
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001261194A
Inventor
Charles D. Boyd
Katalin Csiszar
Sheri F. T. Fong
Youngho Kim
Claude Jourdan Le Saux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii
Original Assignee
University of Hawaii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii filed Critical University of Hawaii
Publication of AU2001261194A1 publication Critical patent/AU2001261194A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
AU2001261194A 2000-05-03 2001-05-03 Novel members of the lysyl oxidases family of amine oxidases related applications Abandoned AU2001261194A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20158700P 2000-05-03 2000-05-03
US60/201,587 2000-05-03
PCT/US2001/014472 WO2001083702A2 (en) 2000-05-03 2001-05-03 Novel members of the lysyl oxidases family of amine oxidases related applications

Publications (1)

Publication Number Publication Date
AU2001261194A1 true AU2001261194A1 (en) 2001-11-12

Family

ID=22746439

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001261194A Abandoned AU2001261194A1 (en) 2000-05-03 2001-05-03 Novel members of the lysyl oxidases family of amine oxidases related applications

Country Status (2)

Country Link
AU (1) AU2001261194A1 (en)
WO (1) WO2001083702A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1315519T3 (en) * 2000-08-08 2011-04-11 Technion Res & Dev Foundation Pharmaceutical compositions and methods that can be used to treat cancer or liver fibrosis
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
IL154036A0 (en) 2000-08-08 2003-07-31 Wyeth Corp A novel member of the lysyl oxidase gene family
GB2438999B (en) * 2003-06-13 2008-01-16 Engelhard Lyon Stimulation of the synthesis and of the activity of an isoform of lysyl oxidase-like LOXL for stimulating the formation of elastic fibres
FR2855968B1 (en) 2003-06-13 2012-11-30 Coletica STIMULATION OF THE SYNTHESIS AND ACTIVITY OF A LYSYL OXIDASE-LIKE LOXL ISOFORM TO STIMULATE THE FORMATION OF ELASTIC FIBERS
FR2855969B1 (en) * 2003-06-13 2012-11-30 Coletica STIMULATION OF THE ACTIVITY OF A LYSYL OXIDASE ISOFORM TO FIGHT CERTAIN PATHOLOGIES DUE TO AN INCOMPLETE, ABSENT OR DISORGANIZED ELASTOGENESIS
JP2007526247A (en) * 2004-01-23 2007-09-13 マサチューセッツ・アイ・アンド・イア・インファーマリー Lysyl oxidase-like 1 (LOXL1) and elastic fiber formation
FR2892635B1 (en) 2005-10-28 2012-11-09 Engelhard Lyon SUBSTANCE FOR RESTORING NORMAL CO-EXPRESSION AND INTERACTION BETWEEN LOX AND NRAGE PROTEINS
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
US8461303B2 (en) 2007-08-02 2013-06-11 Gilead Biologics, Inc. LOX and LOXL2 inhibitors and uses thereof
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
RU2012110585A (en) 2009-08-21 2013-09-27 Джилид Байолоджикс, Инк. CATALYTIC DOMAINS OF LYSYLOXIDASE AND LOXL2
JP6059859B2 (en) * 2009-11-16 2017-01-11 ビーエーエスエフ ビューティ ケア ソリューションズ フランス エスエーエスＢＡＳＦ Ｂｅａｕｔｙ Ｃａｒｅ Ｓｏｌｕｔｉｏｎｓ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． Stimulation of synthesis and activity of LOXL (lysyl oxidase-like) isoforms to stimulate the formation of elastic fibers
CN105622757A (en) * 2010-02-04 2016-06-01 吉联亚生物科技有限公司 Antibodies that bind to lysyl oxidase-like 2(LOXL2) and methods of use therefor
EP2694554A1 (en) 2011-04-08 2014-02-12 Gilead Biologics, Inc. Methods and compositions for normalization of tumor vasculature by inhibition of loxl2
EA201692202A1 (en) 2014-06-11 2017-06-30 Джилид Сайэнс, Инк. METHODS OF TREATING CARDIOVASCULAR DISEASES
EP2990480A1 (en) * 2014-08-29 2016-03-02 Christian-Albrechts-Universität zu Kiel Anti-LOXL4 antibodies and derivatives there
JP2015147798A (en) * 2015-04-20 2015-08-20 ビーエーエスエフ ビューティ ケア ソリューションズ フランス エスエーエス Stimulation of synthesis and of activity of isoform of loxl (lysyl oxidase-like) for stimulating formation of elastic fiber

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140056A (en) * 1999-01-27 2000-10-31 Millennium Pharmaceuticals, Inc. MSP-18 protein and nucleic acid molecules and uses therefor

Also Published As

Publication number Publication date
WO2001083702A2 (en) 2001-11-08
WO2001083702A3 (en) 2005-03-03

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