MXPA02009319A - Inhibidores de p38. - Google Patents
Inhibidores de p38.Info
- Publication number
- MXPA02009319A MXPA02009319A MXPA02009319A MXPA02009319A MXPA02009319A MX PA02009319 A MXPA02009319 A MX PA02009319A MX PA02009319 A MXPA02009319 A MX PA02009319A MX PA02009319 A MXPA02009319 A MX PA02009319A MX PA02009319 A MXPA02009319 A MX PA02009319A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- disease
- optionally substituted
- substituents
- alkyl
- Prior art date
Links
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- 238000000034 method Methods 0.000 claims abstract description 41
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- AOSZTAHDEDLTLQ-AZKQZHLXSA-N (1S,2S,4R,8S,9S,11S,12R,13S,19S)-6-[(3-chlorophenyl)methyl]-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one Chemical compound C([C@@H]1C[C@H]2[C@H]3[C@]([C@]4(C=CC(=O)C=C4[C@@H](F)C3)C)(F)[C@@H](O)C[C@@]2([C@@]1(C1)C(=O)CO)C)N1CC1=CC=CC(Cl)=C1 AOSZTAHDEDLTLQ-AZKQZHLXSA-N 0.000 claims description 2
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- ONBQEOIKXPHGMB-VBSBHUPXSA-N 1-[2-[(2s,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)propan-1-one Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 ONBQEOIKXPHGMB-VBSBHUPXSA-N 0.000 claims description 2
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Classifications
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19135800P | 2000-03-22 | 2000-03-22 | |
| PCT/US2001/009256 WO2001070695A1 (en) | 2000-03-22 | 2001-03-22 | Pyridine derivatives as inhibitors of p38 |
Publications (1)
| Publication Number | Publication Date |
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| MXPA02009319A true MXPA02009319A (es) | 2003-03-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| MXPA02009319A MXPA02009319A (es) | 2000-03-22 | 2001-03-22 | Inhibidores de p38. |
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| CA (1) | CA2403828A1 (enExample) |
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| TW (1) | TWI282334B (enExample) |
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| WO2002014281A1 (en) * | 2000-08-11 | 2002-02-21 | Vertex Pharmaceuticals Incorporated | Pyridine derivatives as inhibitors of p38 |
| PE20020506A1 (es) | 2000-08-22 | 2002-07-09 | Glaxo Group Ltd | Derivados de pirazol fusionados como inhibidores de la proteina cinasa |
| GB0124939D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124931D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124933D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124934D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124936D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124938D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124941D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| CA2474192C (en) | 2002-02-12 | 2011-06-21 | Smithkline Beecham Corporation | Nicotinamide derivates useful as p38 inhibitors |
| GB0217757D0 (en) | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Novel compounds |
| GB0308186D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
| GB0308185D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
| GB0308201D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
| GB0318814D0 (en) * | 2003-08-11 | 2003-09-10 | Smithkline Beecham Corp | Novel compounds |
| GB0908317D0 (en) * | 2009-05-14 | 2009-06-24 | Argenta Discovery Ltd | Pharmaceutical compounds and compositions |
| US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945418A (en) * | 1996-12-18 | 1999-08-31 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| US6147080A (en) * | 1996-12-18 | 2000-11-14 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| WO1998052941A1 (en) * | 1997-05-22 | 1998-11-26 | G.D. Searle And Co. | PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS |
| DK1043995T3 (da) * | 1997-12-22 | 2007-03-05 | Bayer Pharmaceuticals Corp | Inhibering af p38 kinaseaktivitet ved anvendelse af aryl- og heteroaryl-substituerede, heterocykliske urinstoffer |
| MY132496A (en) * | 1998-05-11 | 2007-10-31 | Vertex Pharma | Inhibitors of p38 |
-
2001
- 2001-03-22 JP JP2001568907A patent/JP2003528084A/ja not_active Withdrawn
- 2001-03-22 WO PCT/US2001/009256 patent/WO2001070695A1/en not_active Ceased
- 2001-03-22 MX MXPA02009319A patent/MXPA02009319A/es not_active Application Discontinuation
- 2001-03-22 CA CA002403828A patent/CA2403828A1/en not_active Abandoned
- 2001-03-22 TW TWNOVELCOMA patent/TWI282334B/zh not_active IP Right Cessation
- 2001-03-22 AU AU2001247700A patent/AU2001247700A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003528084A (ja) | 2003-09-24 |
| TWI282334B (en) | 2007-06-11 |
| WO2001070695A1 (en) | 2001-09-27 |
| CA2403828A1 (en) | 2001-09-27 |
| AU2001247700A1 (en) | 2001-10-03 |
| WO2001070695A8 (en) | 2001-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |