MXPA01005745A - Tipificacion de la toxicidad utilizando cuerpos embrioides. - Google Patents

Tipificacion de la toxicidad utilizando cuerpos embrioides.

Info

Publication number
MXPA01005745A
MXPA01005745A MXPA01005745A MXPA01005745A MXPA01005745A MX PA01005745 A MXPA01005745 A MX PA01005745A MX PA01005745 A MXPA01005745 A MX PA01005745A MX PA01005745 A MXPA01005745 A MX PA01005745A MX PA01005745 A MXPA01005745 A MX PA01005745A
Authority
MX
Mexico
Prior art keywords
embryoid bodies
typing
toxicity
toxicity typing
embryoid
Prior art date
Application number
MXPA01005745A
Other languages
English (en)
Inventor
H Ralph Snodgrass
Original Assignee
Vistagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vistagen Inc filed Critical Vistagen Inc
Publication of MXPA01005745A publication Critical patent/MXPA01005745A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
MXPA01005745A 1998-12-09 1999-12-09 Tipificacion de la toxicidad utilizando cuerpos embrioides. MXPA01005745A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11164098P 1998-12-09 1998-12-09
US45793199A 1999-12-08 1999-12-08
PCT/US1999/029384 WO2000034525A1 (en) 1998-12-09 1999-12-09 Toxicity typing using embryoid bodies

Publications (1)

Publication Number Publication Date
MXPA01005745A true MXPA01005745A (es) 2003-07-14

Family

ID=26809099

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01005745A MXPA01005745A (es) 1998-12-09 1999-12-09 Tipificacion de la toxicidad utilizando cuerpos embrioides.

Country Status (8)

Country Link
US (1) US20010039006A1 (es)
EP (1) EP1137809A1 (es)
JP (1) JP2002531852A (es)
KR (1) KR20010080722A (es)
AU (1) AU778844B2 (es)
CA (1) CA2353309A1 (es)
MX (1) MXPA01005745A (es)
WO (1) WO2000034525A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL129966A (en) * 1999-05-14 2009-12-24 Technion Res & Dev Foundation ISOLATED HUMAN EMBRYOID BODIES (hEB) DERIVED FROM HUMAN EMBRYONIC STEM CELLS
AU2005202789B2 (en) * 1999-05-14 2007-04-05 Technion Research And Development Foundation Ltd. Differentiated human embryoid cells and a method for producing them
IL152179A (en) 2000-04-10 2009-06-15 Teva Pharma Stable pharmaceutical compositions containing 7-substituted-3,5- dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
JP2004503256A (ja) 2000-06-14 2004-02-05 ビスタジェン　インコーポレイテッド 肝臓幹細胞を使用する毒性分類
EP1364049A2 (en) * 2000-07-31 2003-11-26 Gene Logic, Inc. Molecular toxicology modeling
US7590493B2 (en) * 2000-07-31 2009-09-15 Ocimum Biosolutions, Inc. Methods for determining hepatotoxins
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
CA2447357A1 (en) * 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
CA2452897A1 (en) * 2001-07-10 2003-08-21 Gene Logic, Inc. Cardiotoxin molecular toxicology modeling
US20070054269A1 (en) * 2001-07-10 2007-03-08 Mendrick Donna L Molecular cardiotoxicology modeling
US7447594B2 (en) * 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
EP1476747A4 (en) * 2002-01-31 2008-06-11 Ocimum Biosolutions Inc MOLECULAR HEPATOTOXICOLOGICAL MODELING
JP2007501617A (ja) * 2003-08-07 2007-02-01 ジーン ロジック インコーポレイテッド 初代ラット肝細胞毒性モデリング
US20080281526A1 (en) * 2004-03-22 2008-11-13 Diggans James C Methods For Molecular Toxicology Modeling
EP1751303A2 (en) * 2004-04-07 2007-02-14 Gene Logic, Inc. Hepatotoxicity molecular models
DK3070174T3 (da) 2004-05-11 2020-01-27 Ncardia Ag Opsporing af lægemidler på grundlag af in vitro-differentierede celler
US20080254002A1 (en) * 2004-09-03 2008-10-16 Edelberg Jay M Bone Marrow Derived Oct3/4+ Stem Cells
US20090220996A1 (en) * 2007-03-06 2009-09-03 Reliance Life Sciences Pvt Ltd. In vitro Assay Methods for Classifying Embryotoxicity of Compounds
US10125388B2 (en) * 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
JP5428527B2 (ja) * 2008-06-03 2014-02-26 住友化学株式会社 化学物質が有する発生毒性の予測方法
GB0911060D0 (en) * 2009-06-26 2009-08-12 Ge Healthcare Uk Ltd Methods for predicting the toxicity of a chemical
WO2011115993A2 (en) * 2010-03-15 2011-09-22 The Johns Hopkins University Method for determining substance non-toxicity
CN110070922B (zh) * 2017-08-22 2022-10-04 苏州市药品检验检测研究中心（苏州市药品不良反应监测中心） 一种化学品眼刺激性的评价方法
CN109298063A (zh) * 2018-10-15 2019-02-01 广东工业大学 一种快速检测面膜天然成分的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS191501B1 (en) * 1976-04-02 1979-07-31 Richard Jelinek Method of testing the embryotoxicity on the chicken embryo
WO1992010588A1 (en) 1990-12-06 1992-06-25 Affymax Technologies N.V. Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
EP0597964A4 (en) * 1991-08-07 1994-11-30 Einstein Coll Med PROLIFERATION OF HEPATOCYTE PRECURSORS.
DE19525285C2 (de) * 1995-06-28 1999-04-15 Inst Pflanzengenetik & Kultur In vitro Testverfahren zum Nachweis Chemikalien-induzierter embryotoxischer/teratogener Effekte
WO1997013877A1 (en) * 1995-10-12 1997-04-17 Lynx Therapeutics, Inc. Measurement of gene expression profiles in toxicity determination
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
DE19606207A1 (de) * 1996-02-21 1997-08-28 Univ Duesseldorf H Heine Verfahren zur Bestimmung der Phototoxizität und/oder Photosensibilität von Stoffen oder Stoffgemischen sowie dessen Verwendung
US5811297A (en) * 1996-03-07 1998-09-22 Amba Biosciences, Llc Immortalized hematopoietic cell lines, cell system thereof with stromal cells, in vitro, ex vivo and in vivo uses, & in vitro generation of dendritic cells and macrophages
AU3392697A (en) * 1996-06-14 1998-01-07 Regents Of The University Of California, The (in vitro) derivation and culture of primate pluripotent stem cells and therapeutic uses thereof
US6299858B1 (en) * 1998-02-23 2001-10-09 Phylonix Pharmaceuticals, Inc. Methods of screening agents for activity using teleosts

Also Published As

Publication number Publication date
KR20010080722A (ko) 2001-08-22
EP1137809A1 (en) 2001-10-04
AU1938500A (en) 2000-06-26
US20010039006A1 (en) 2001-11-08
CA2353309A1 (en) 2000-06-15
AU778844B2 (en) 2004-12-23
WO2000034525A1 (en) 2000-06-15
WO2000034525A8 (en) 2001-02-08
JP2002531852A (ja) 2002-09-24

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