MXPA01002674A - Un metodo para producir una proteina de la superfamilia de inmunoglobulina funcional. - Google Patents
Un metodo para producir una proteina de la superfamilia de inmunoglobulina funcional.Info
- Publication number
- MXPA01002674A MXPA01002674A MXPA01002674A MXPA01002674A MXPA01002674A MX PA01002674 A MXPA01002674 A MX PA01002674A MX PA01002674 A MXPA01002674 A MX PA01002674A MX PA01002674 A MXPA01002674 A MX PA01002674A MX PA01002674 A MXPA01002674 A MX PA01002674A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- mhc
- cell
- process according
- functional
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199801155 | 1998-09-14 | ||
PCT/DK1999/000484 WO2000015665A2 (en) | 1998-09-14 | 1999-09-14 | A method of producing a functional immunoglobulin superfamily protein |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA01002674A true MXPA01002674A (es) | 2002-06-04 |
Family
ID=8101632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA01002674A MXPA01002674A (es) | 1998-09-14 | 1999-09-14 | Un metodo para producir una proteina de la superfamilia de inmunoglobulina funcional. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1114063A2 (ja) |
JP (1) | JP2002524104A (ja) |
KR (1) | KR20010075108A (ja) |
CN (1) | CN1326466A (ja) |
AU (1) | AU771239C (ja) |
BR (1) | BR9914491A (ja) |
CA (1) | CA2343313A1 (ja) |
MX (1) | MXPA01002674A (ja) |
NZ (1) | NZ511031A (ja) |
WO (1) | WO2000015665A2 (ja) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2747357T3 (es) | 2001-03-14 | 2020-03-10 | Dako Denmark As | Construcciones de moléculas MHC y sus usos para el diagnóstico y terapia |
WO2003097669A2 (en) * | 2002-05-17 | 2003-11-27 | Københavns Universitet | Method for purifying denatured proteins having a desired disulfide bond configuration |
US20040072262A1 (en) | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
WO2004072112A2 (en) * | 2003-02-11 | 2004-08-26 | Københavns Universitet | A method for formulating mhc-like molecules for long time storage |
EP1706720A4 (en) * | 2003-10-31 | 2007-02-28 | Vitatex Inc | BLOOD TEST PROTOTYPES AND METHOD FOR DETECTING CIRCULATING TUMOR AND ENDOTHELIAL CELLS |
US7678379B2 (en) | 2004-06-17 | 2010-03-16 | Beckman Coulter, Inc. | Mycobacterium tuberculosis epitopes and methods of use thereof |
DE602005022082D1 (de) | 2004-08-19 | 2010-08-12 | Biogen Idec Inc | Rückfaltung von proteinen der transforming-growth-factor-beta-familie |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
CL2007002225A1 (es) * | 2006-08-03 | 2008-04-18 | Astrazeneca Ab | Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un |
EP2361930A3 (en) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases |
TWI445544B (zh) | 2007-05-01 | 2014-07-21 | Biogen Idec Inc | 增進血管形成之組合物及方法 |
EP3023436A1 (en) | 2007-07-03 | 2016-05-25 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
DE17196350T1 (de) | 2007-07-09 | 2018-12-27 | Genentech, Inc. | Verhindern der disulfid-bindungsreduktion während der rekombinanten herstellung von polypeptiden |
WO2009039854A2 (en) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
GB2453589A (en) | 2007-10-12 | 2009-04-15 | King S College London | Protease inhibition |
DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
CN103364558A (zh) * | 2013-07-17 | 2013-10-23 | 江阴泽成生物技术有限公司 | 一种人肿瘤标志物癌胚抗原(cea)的磁微粒化学发光免疫分析试剂盒及其检测方法 |
CN109402036A (zh) * | 2018-11-07 | 2019-03-01 | 河北科技师范学院 | 牛源肠炎沙门菌trxB基因缺失的应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5314813A (en) * | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
WO1993022332A2 (en) * | 1992-04-24 | 1993-11-11 | Board Of Regents, The University Of Texas System | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
WO1994006813A1 (en) * | 1992-09-15 | 1994-03-31 | The Rockefeller University | Major histocompatibility complex molecules and modifications thereof |
EP0726777A4 (en) * | 1993-10-25 | 2002-04-24 | Anergen Inc | Procarciotic expression of MHC proteins |
AU3036597A (en) * | 1996-05-21 | 1997-12-09 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for using peptide complexes/major histocompatibility complex to obtain or purify antigen-specific t cells and to stimulate t cells |
-
1999
- 1999-09-14 WO PCT/DK1999/000484 patent/WO2000015665A2/en not_active Application Discontinuation
- 1999-09-14 CN CN99813211A patent/CN1326466A/zh active Pending
- 1999-09-14 NZ NZ511031A patent/NZ511031A/en unknown
- 1999-09-14 MX MXPA01002674A patent/MXPA01002674A/es unknown
- 1999-09-14 BR BR9914491-3A patent/BR9914491A/pt not_active IP Right Cessation
- 1999-09-14 CA CA002343313A patent/CA2343313A1/en not_active Abandoned
- 1999-09-14 AU AU55047/99A patent/AU771239C/en not_active Ceased
- 1999-09-14 JP JP2000570203A patent/JP2002524104A/ja active Pending
- 1999-09-14 KR KR1020017003306A patent/KR20010075108A/ko not_active Application Discontinuation
- 1999-09-14 EP EP99941420A patent/EP1114063A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2000015665A2 (en) | 2000-03-23 |
WO2000015665A3 (en) | 2000-08-17 |
AU771239C (en) | 2004-10-14 |
EP1114063A2 (en) | 2001-07-11 |
JP2002524104A (ja) | 2002-08-06 |
AU5504799A (en) | 2000-04-03 |
KR20010075108A (ko) | 2001-08-09 |
CA2343313A1 (en) | 2000-03-23 |
BR9914491A (pt) | 2002-01-15 |
AU771239B2 (en) | 2004-03-18 |
NZ511031A (en) | 2003-11-28 |
CN1326466A (zh) | 2001-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA01002674A (es) | Un metodo para producir una proteina de la superfamilia de inmunoglobulina funcional. | |
West et al. | Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells | |
Frayser et al. | Empty and Peptide-Loaded Class II Major Histocompatibility Complex Proteins Produced by Expression inEscherichia coliand Foldingin Vitro | |
DE69833949T2 (de) | Mutierte klasse-i-mhc-moleküle | |
EP1844072B1 (en) | Mhc oligomer and method of making the same | |
US20240294601A1 (en) | Peptide deficient-mhc class i/chaperone compositions and methods | |
Parker et al. | Peptide binding to HLA-A2 and HLA-B27 isolated from Escherichia coli. Reconstitution of HLA-A2 and HLA-B27 heavy chain/beta 2-microglobulin complexes requires specific peptides. | |
EP1882700B1 (en) | Biotinylated MHC complexes and their uses | |
Ignatowicz et al. | Cell surface expression of class II MHC proteins bound by a single peptide. | |
JP2004503213A (ja) | 1本鎖クラスi主要組織適合性複合体、それをコードする構築物およびそれを生成する方法 | |
CA3095741A1 (en) | Peptide-mhc compacts | |
Hochman et al. | Specific associations of fluorescent beta-2-microglobulin with cell surfaces. The affinity of different H-2 and HLA antigens for beta-2-microglobulin. | |
US20090028884A1 (en) | Oligomeric receptor ligand pair member complexes | |
Purcell et al. | Dissecting the role of peptides in the immune response: theory, practice and the application to vaccine design | |
JP2004524019A (ja) | 内因性蛍光自己多量体化mhc融合タンパク質およびその複合体 | |
JP2008528484A (ja) | 分子間の非共有的結合性相互作用の破壊のための手段および方法 | |
CN114174329A (zh) | 肽-mhc复合物 | |
CA2308463A1 (en) | Cd8 as an inhibitor of the cellular immune system | |
US11814420B2 (en) | Peptide deficient-MHC class I/chaperone compositions and methods | |
Crumpton et al. | Molecular structure of the gene products of the human HLA system: isolation and characterization of HLA-A,-B,-C and Ia antigens | |
Moro et al. | Generation of functional HLA-DR* 1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides | |
Nag et al. | Antigenic peptide binding to MHC class II molecules at increased peptide concentrations | |
Li et al. | Kinetics of interaction of HLA-B2705 with natural killer cell immunoglobulin-like receptor 3DS1 | |
Tussey et al. | General introduction to the MHC | |
US20220275050A1 (en) | High yield production and use of enzymatic-exchangeable peptide major histocompatibility complex class i single chain trimer tetramer |