MX9804289A - Cisteina proteasa similar a la enzima de conversion interleucina-1beta. - Google Patents

Cisteina proteasa similar a la enzima de conversion interleucina-1beta.

Info

Publication number
MX9804289A
MX9804289A MX9804289A MX9804289A MX9804289A MX 9804289 A MX9804289 A MX 9804289A MX 9804289 A MX9804289 A MX 9804289A MX 9804289 A MX9804289 A MX 9804289A MX 9804289 A MX9804289 A MX 9804289A
Authority
MX
Mexico
Prior art keywords
lice3
interleukin
beta
converting enzyme
cysteine protease
Prior art date
Application number
MX9804289A
Other languages
English (en)
Inventor
Shao-Chieh Juan
Frederick A Fletcher
Scott D Patterson
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX9804289A publication Critical patent/MX9804289A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se ha identificado un nuevo miembro de una familia de cisteína proteasas similares a ICE. La familia de proteasa se denomino LICE (Similar a ICE) y el miembro de la familia que se describe aquí es LICE3. Se exponen polipéptidos LICE3, ácidos nucleicos que codifican LICE3 y vectores y células huésped para la expresion de LICE3. También se exponen métodos para identificar agonistas y antagonistas de LICE3 y métodos para el tratamiento de desordenes caracterizados por la apoptosis alterada.
MX9804289A 1996-10-01 1998-05-29 Cisteina proteasa similar a la enzima de conversion interleucina-1beta. MX9804289A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/724,378 US6512104B1 (en) 1996-10-01 1996-10-01 Interleukin-1β converting enzyme like cysteine protease

Publications (1)

Publication Number Publication Date
MX9804289A true MX9804289A (es) 1998-09-30

Family

ID=24910195

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804289A MX9804289A (es) 1996-10-01 1998-05-29 Cisteina proteasa similar a la enzima de conversion interleucina-1beta.

Country Status (6)

Country Link
US (2) US6512104B1 (es)
EP (1) EP0870038A1 (es)
JP (1) JP2001502171A (es)
CA (1) CA2236914A1 (es)
MX (1) MX9804289A (es)
WO (1) WO1998014598A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326479B1 (en) * 1998-01-27 2001-12-04 Boston Probes, Inc. Synthetic polymers and methods, kits or compositions for modulating the solubility of same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
AU7250494A (en) 1994-06-23 1996-01-19 Human Genome Sciences, Inc. Interleukin-1 beta converting enzyme like apoptosis protease-1 and 2
FR2723378B1 (fr) 1994-08-02 1996-10-31 Roussel Uclaf Sequence d'adn codant pour une proteine humaine tx apparentee a l'enzyme de conversion de l'interleukine-1beta, proteine tx, procede de production, compositions pharmaceutiques et leurs applications
US5786173A (en) 1996-03-19 1998-07-28 Idun Pharmaceuticals, Inc. MCH4 and MCH5, apoptotic protease, nucleic acids encoding and methods of use
US5851815A (en) * 1996-03-19 1998-12-22 Idun Pharmaceuticals, Inc. MCH4 and MCH5, apoptotic proteases
WO1998000554A1 (en) * 1996-07-03 1998-01-08 Genetics Institute, Inc. Protease fmh-1, an ice/ced-like protease

Also Published As

Publication number Publication date
AU724214B2 (en) 2000-09-14
CA2236914A1 (en) 1998-04-09
EP0870038A1 (en) 1998-10-14
AU4430297A (en) 1998-04-24
US20030170812A1 (en) 2003-09-11
WO1998014598A1 (en) 1998-04-09
JP2001502171A (ja) 2001-02-20
US6512104B1 (en) 2003-01-28

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