MX9802025A - Derivados de fenol, composiciones farmaceuticas que los contienen y el uso de los mismos. - Google Patents
Derivados de fenol, composiciones farmaceuticas que los contienen y el uso de los mismos.Info
- Publication number
- MX9802025A MX9802025A MX9802025A MX9802025A MX9802025A MX 9802025 A MX9802025 A MX 9802025A MX 9802025 A MX9802025 A MX 9802025A MX 9802025 A MX9802025 A MX 9802025A MX 9802025 A MX9802025 A MX 9802025A
- Authority
- MX
- Mexico
- Prior art keywords
- phenol derivatives
- pharmaceutical activity
- nmda receptor
- receptor sites
- prodrugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Los compuestos de la formula (I), y las sales farmacéuticamente aceptables de los mismos, en la que R es como aquí se ha definido, se usan como profármacos en la preparacion de composiciones para un antagonista competitivo del ácido N-metil-D-aspártico que bloquean los sitios de receptor NMDA y son de utilidad en el tratamiento de ciertos trastornos y enfermedades que responden al bloqueo de los sitios de receptor NMDA, incluyendo traumatismo craneal, apoplejía, demencia multiinfarto y otros trastornos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US385495P | 1995-09-15 | 1995-09-15 | |
| US003854 | 1995-09-15 | ||
| PCT/IB1996/000668 WO1997010240A1 (en) | 1995-09-15 | 1996-07-11 | Phenol derivatives with pharmaceutical activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9802025A true MX9802025A (es) | 1998-08-30 |
| MXPA98002025A MXPA98002025A (es) | 1998-11-12 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11509839A (ja) | 1999-08-31 |
| WO1997010240A1 (en) | 1997-03-20 |
| EP0859773A1 (en) | 1998-08-26 |
| CA2232059A1 (en) | 1997-03-20 |
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