MX9710291A - Inhibidores ligantes de proteinas de fijacion con factor de crecimiento del tipo de insulina y metodos de uso para los mismos. - Google Patents

Inhibidores ligantes de proteinas de fijacion con factor de crecimiento del tipo de insulina y metodos de uso para los mismos.

Info

Publication number
MX9710291A
MX9710291A MX9710291A MX9710291A MX9710291A MX 9710291 A MX9710291 A MX 9710291A MX 9710291 A MX9710291 A MX 9710291A MX 9710291 A MX9710291 A MX 9710291A MX 9710291 A MX9710291 A MX 9710291A
Authority
MX
Mexico
Prior art keywords
insulin
methods
growth factor
binding proteins
ligand inhibitors
Prior art date
Application number
MX9710291A
Other languages
English (en)
Other versions
MXPA97010291A (es
Inventor
Dominic Behan
Nicholas Ling
Xin-Jun Liu
Amitabh Gaur
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of MX9710291A publication Critical patent/MX9710291A/es
Publication of MXPA97010291A publication Critical patent/MXPA97010291A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Los métodos para aumentar el nivel de las proteínas libres biologicamente activas, incluyendo los factores de crecimiento del tipo de insulina, y se proporciona un método para el tratamiento de condiciones de respueta IGF. Los métodos generalmente comprendidos que administran uno o más inhibidores ligantes que inhiben la fijacion de la proteína a una o más proteínas de fijacion con factores de crecimiento del tipo de insulina. Los inhibidores ligantes adecuados incluyen análogos de IGF-1 o IGF-II e inhibidores de pequeñas moléculas.
MXPA/A/1997/010291A 1996-04-17 1997-12-17 Inhibidores ligantes de proteinas de fijacion confactor de crecimiento del tipo de insulina y metodos de uso para los mismos MXPA97010291A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63393496A 1996-04-17 1996-04-17
US633934 1996-04-17

Publications (2)

Publication Number Publication Date
MX9710291A true MX9710291A (es) 1998-08-30
MXPA97010291A MXPA97010291A (es) 1998-11-12

Family

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Also Published As

Publication number Publication date
WO1997039032A1 (en) 1997-10-23
CA2224859A1 (en) 1997-10-23
EP0854884A1 (en) 1998-07-29
AU2676297A (en) 1997-11-07
JPH11508608A (ja) 1999-07-27

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