MX9708421A - Esteres de carbapenemas. - Google Patents

Esteres de carbapenemas.

Info

Publication number
MX9708421A
MX9708421A MX9708421A MX9708421A MX9708421A MX 9708421 A MX9708421 A MX 9708421A MX 9708421 A MX9708421 A MX 9708421A MX 9708421 A MX9708421 A MX 9708421A MX 9708421 A MX9708421 A MX 9708421A
Authority
MX
Mexico
Prior art keywords
carbapenems
esters
methyl
isobutyryloxymethyl
benzoyloxymethyl
Prior art date
Application number
MX9708421A
Other languages
English (en)
Other versions
MXPA97008421A (es
Inventor
George Burton
Stephen Frederick Moss
Alfred John Eglington
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9508956.1A external-priority patent/GB9508956D0/en
Priority claimed from GBGB9508955.3A external-priority patent/GB9508955D0/en
Priority claimed from GBGB9508957.9A external-priority patent/GB9508957D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MXPA97008421A publication Critical patent/MXPA97008421A/es
Publication of MX9708421A publication Critical patent/MX9708421A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D477/08—Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un compuesto de la formula (I), en donde R se selecciona a partir del grupo que consiste en isobutiriloximetilo, (5-metil-2-oxo-1,3-dioxolen-4-il)metilo, y benzociloximetilo, es util en el tratamiento de infecciones bacterianas.
MX9708421A 1995-05-03 1996-05-02 Esteres de carbapenemas. MX9708421A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9508956.1A GB9508956D0 (en) 1995-05-03 1995-05-03 Novel compounds
GB9508956.1 1995-05-03
GB9508957.9 1995-05-03
GB9508955.3 1995-05-03
GBGB9508955.3A GB9508955D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508957.9A GB9508957D0 (en) 1995-05-03 1995-05-03 Novel compounds
PCT/EP1996/001880 WO1996034868A1 (en) 1995-05-03 1996-05-02 Esters of carbapenems

Publications (2)

Publication Number Publication Date
MXPA97008421A MXPA97008421A (es) 1998-02-01
MX9708421A true MX9708421A (es) 1998-02-28

Family

ID=27267696

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9708421A MX9708421A (es) 1995-05-03 1996-05-02 Esteres de carbapenemas.

Country Status (22)

Country Link
EP (1) EP0823910A1 (es)
JP (1) JPH11504910A (es)
KR (1) KR19990008355A (es)
CN (1) CN1185783A (es)
AR (1) AR005416A1 (es)
AU (1) AU5813996A (es)
BG (1) BG102014A (es)
BR (1) BR9608313A (es)
CA (1) CA2217990A1 (es)
CZ (1) CZ347597A3 (es)
EA (1) EA199700293A1 (es)
HU (1) HUP9801066A3 (es)
IL (1) IL118092A0 (es)
MA (1) MA23853A1 (es)
MX (1) MX9708421A (es)
NO (1) NO974994D0 (es)
OA (1) OA10632A (es)
PE (1) PE50697A1 (es)
PL (1) PL323141A1 (es)
SK (1) SK146497A3 (es)
TR (1) TR199701286T1 (es)
WO (1) WO1996034868A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902659A1 (fr) 2006-06-23 2007-12-28 Pierre Fabre Medicament Sa Ester de dha et son utilisation dans le traitement et la prevention des maladies cardiovasculaires
WO2013157583A1 (ja) * 2012-04-18 2013-10-24 大日本住友製薬株式会社 新規カルバペネム化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
CA1212105A (en) * 1980-04-30 1986-09-30 Shoji Ikeda Ampicillin esters and production thereof
AU7467194A (en) * 1993-08-18 1995-03-14 Sankyo Company Limited Crystalline carbapenem derivatives
KR960705827A (ko) * 1993-10-29 1996-11-08 데이비드 로버츠 2-(피라졸-3-일)카르바페넴 유도체(2-(pyrazol-3-yl)carbapenem derivatives)

Also Published As

Publication number Publication date
NO974994L (no) 1997-10-30
CN1185783A (zh) 1998-06-24
PL323141A1 (en) 1998-03-16
SK146497A3 (en) 1998-05-06
MA23853A1 (fr) 1996-12-31
BG102014A (en) 1998-11-30
HUP9801066A2 (hu) 1998-08-28
BR9608313A (pt) 1999-01-26
OA10632A (en) 2002-09-16
WO1996034868A1 (en) 1996-11-07
EA199700293A1 (ru) 1998-06-25
CA2217990A1 (en) 1996-11-07
CZ347597A3 (cs) 1998-08-12
AR005416A1 (es) 1999-06-23
EP0823910A1 (en) 1998-02-18
IL118092A0 (en) 1996-09-12
HUP9801066A3 (en) 1999-01-28
AU5813996A (en) 1996-11-21
TR199701286T1 (xx) 1998-02-21
NO974994D0 (no) 1997-10-30
JPH11504910A (ja) 1999-05-11
KR19990008355A (ko) 1999-01-25
PE50697A1 (es) 1997-12-18

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