MX9705185A - Particula de resina, material medico y preparacion farmaceutica que contiene dicha particula de resina. - Google Patents
Particula de resina, material medico y preparacion farmaceutica que contiene dicha particula de resina.Info
- Publication number
- MX9705185A MX9705185A MX9705185A MX9705185A MX9705185A MX 9705185 A MX9705185 A MX 9705185A MX 9705185 A MX9705185 A MX 9705185A MX 9705185 A MX9705185 A MX 9705185A MX 9705185 A MX9705185 A MX 9705185A
- Authority
- MX
- Mexico
- Prior art keywords
- resin particle
- cilostazol
- pharmaceutical preparation
- medical material
- preparation containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
Se provee una partícula de resina que comprende un copolímero de etileno y alcohol vinílico y de 5 a 90% en peso de cilostazol incorporado en el mismo, y tiene un tamaño de partícula no mayor de 2,000 æm; la partícula de resina, al ser administrada oralmente, permite que la concentracion de cilostazol en sangre se mantenga constante durante un periodo prolongado y por lo tanto alivia notablemente los efectos secundarios tales como cefalgia y fuerte malestar, que pueden ocasionarse de otra manera por la liberacion rápida de cilostazol en el cuerpo.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7-002287 | 1995-01-10 | ||
JP7/2287 | 1995-01-10 | ||
JP228795 | 1995-01-10 | ||
PCT/JP1996/000004 WO1996021448A1 (en) | 1995-01-10 | 1996-01-04 | Resin particle, medical material and pharmaceutical preparation containing said resin particle |
Publications (2)
Publication Number | Publication Date |
---|---|
MX9705185A true MX9705185A (es) | 1997-10-31 |
MXPA97005185A MXPA97005185A (es) | 1998-07-03 |
Family
ID=
Also Published As
Publication number | Publication date |
---|---|
CA2208571A1 (en) | 1996-07-18 |
AU4357096A (en) | 1996-07-31 |
CN1168102A (zh) | 1997-12-17 |
WO1996021448A1 (en) | 1996-07-18 |
KR19980701292A (ko) | 1998-05-15 |
EP0794778A1 (en) | 1997-09-17 |
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