MX9700881A - Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica. - Google Patents

Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica.

Info

Publication number
MX9700881A
MX9700881A MX9700881A MX9700881A MX9700881A MX 9700881 A MX9700881 A MX 9700881A MX 9700881 A MX9700881 A MX 9700881A MX 9700881 A MX9700881 A MX 9700881A MX 9700881 A MX9700881 A MX 9700881A
Authority
MX
Mexico
Prior art keywords
cholanes
pregnanes
change
vomeropherin
hypothalamic function
Prior art date
Application number
MX9700881A
Other languages
English (en)
Inventor
Clive L Jennings-White
David L Berliner
Adams Nathan William
Original Assignee
Pherin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/286,073 external-priority patent/US5563131A/en
Application filed by Pherin Corp filed Critical Pherin Corp
Publication of MX9700881A publication Critical patent/MX9700881A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Abstract

La invencion se refiere a un método para alterar la funcion hipotalámica en un individuo. Este método comprende administrar nasalmente una vomeroferina humana, por ejemplo un esteroide de pregnano o colano, o una composicion farmacéutica que contenga una vomeroferina, de manera que esta vomeroferina se ligue a un receptor neuroepitelial específico. Se administra el esteroide a los esteroides en la forma de una composicion fermacéutica que contiene uno o más portadores aceptables farmacéuticamente. Otras modalidades de la invencion incluyen composiciones farmacéuticas que contienen los esteroides.
MX9700881A 1994-08-04 1995-08-04 Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica. MX9700881A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/286,073 US5563131A (en) 1994-08-04 1994-08-04 Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US08/510,957 US5994333A (en) 1994-08-04 1995-08-03 Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
PCT/US1995/009634 WO1996004296A1 (en) 1994-08-04 1995-08-04 Pregnanes and cholanes as neurochemical initiators of change in hypothalamic function

Publications (1)

Publication Number Publication Date
MX9700881A true MX9700881A (es) 1997-04-30

Family

ID=26963568

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700881A MX9700881A (es) 1994-08-04 1995-08-04 Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica.

Country Status (11)

Country Link
US (1) US5994333A (es)
EP (1) EP0775154A4 (es)
CN (1) CN1173181A (es)
BR (1) BR9508519A (es)
CA (1) CA2196690C (es)
CZ (1) CZ32997A3 (es)
FI (1) FI970447A (es)
MX (1) MX9700881A (es)
NO (1) NO311328B1 (es)
NZ (1) NZ291056A (es)
PL (1) PL318521A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045514A1 (en) * 2001-05-03 2003-03-06 Louis Monti 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors
CA2698903A1 (en) * 2007-09-17 2009-03-26 Human Pheromone Sciences, Inc. Fragrance compositions and other compositions which contain naturally occurring substances found in corals
CN102056484B (zh) * 2008-04-09 2014-10-29 费林药业公司 用于热潮红的类固醇治疗
US10322138B2 (en) 2012-12-28 2019-06-18 Pherin Pharmaceuticals, Inc. Treatment of depressive disorders
CN114128658B (zh) * 2021-11-25 2023-03-24 中国水产科学研究院黑龙江水产研究所 一种用于人工鱼巢的改性椰丝材料的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
AU698834B2 (en) * 1993-05-24 1998-11-12 Purdue Pharma Ltd. Methods and compositions for inducing sleep
DE69333352T2 (de) * 1993-06-15 2004-07-22 Pherin Corp., Menlo Park Androstansteroide als neurochemische initiatoren einer veränderung der hypothalamusfunktion beim menschen und verwandte pharmazeutische präparate und verfahren
BR9307866A (pt) * 1993-06-15 1996-07-30 Pherin Corp Esteróides estreno como iniciadores neuroquímicos de mudança em funçao hipotalamica humana e composiçoes farmaceuticas relacionadas e processos

Also Published As

Publication number Publication date
FI970447A0 (fi) 1997-02-03
CA2196690C (en) 2008-01-08
NO311328B1 (no) 2001-11-19
FI970447A (fi) 1997-04-03
US5994333A (en) 1999-11-30
CN1173181A (zh) 1998-02-11
EP0775154A4 (en) 2001-05-09
CA2196690A1 (en) 1996-02-15
NO970472D0 (no) 1997-02-03
CZ32997A3 (en) 1997-09-17
EP0775154A1 (en) 1997-05-28
PL318521A1 (en) 1997-06-23
NO970472L (no) 1997-04-03
NZ291056A (en) 2001-03-30
BR9508519A (pt) 1998-07-14

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