MX9700574A - Metodo para establecer la secrecion de estrogeno tonico ovarico para regimenes terapeuticos prolongados. - Google Patents

Metodo para establecer la secrecion de estrogeno tonico ovarico para regimenes terapeuticos prolongados.

Info

Publication number
MX9700574A
MX9700574A MX9700574A MX9700574A MX9700574A MX 9700574 A MX9700574 A MX 9700574A MX 9700574 A MX9700574 A MX 9700574A MX 9700574 A MX9700574 A MX 9700574A MX 9700574 A MX9700574 A MX 9700574A
Authority
MX
Mexico
Prior art keywords
gnrh antagonist
establishment
therapeutic regimens
estrogen
gonadal
Prior art date
Application number
MX9700574A
Other languages
English (en)
Inventor
Gary D Hodgen
Audrey Philips
Original Assignee
Hampton Roads Medical College
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26959766&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9700574(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/467,860 external-priority patent/US5658884A/en
Application filed by Hampton Roads Medical College, Ortho Pharma Corp filed Critical Hampton Roads Medical College
Publication of MX9700574A publication Critical patent/MX9700574A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un régimen para el manejo terapéutico de una condicion dependiente gonadal-esteroide en un mamífero constituye la reduccion del suministro de estrogeno del mismo por medio de la administracion de un antagonista de GnRH en una cantidad efectiva para inhibir la proliferacion de tejido endometrial sin detener substancialmente la produccion de estrogeno endogeno. Un método para determinar se el suministro de estrogeno reducido en un individuo es tal que la concentracion de estradiol ha sido suprimida hasta un nivel optimizado apropiado para el manejo terapéutico de la condicion dependiente gonadal-esteroide tal como endometriosis en ese individuo mediante la administracion de un antagonista de GnRH a un nivel de dosis dado involucra la titulacion de la dosis, por ejemplo, al conducir una prueba de estimulacion con progesterona y dosis de régimen optimas de un antagonista de GnRH.
MX9700574A 1994-07-22 1995-07-18 Metodo para establecer la secrecion de estrogeno tonico ovarico para regimenes terapeuticos prolongados. MX9700574A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27959394A 1994-07-22 1994-07-22
US08/467,860 US5658884A (en) 1994-07-22 1995-06-06 Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens
PCT/US1995/008996 WO1996003138A1 (en) 1994-07-22 1995-07-18 Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens

Publications (1)

Publication Number Publication Date
MX9700574A true MX9700574A (es) 1997-12-31

Family

ID=26959766

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700574A MX9700574A (es) 1994-07-22 1995-07-18 Metodo para establecer la secrecion de estrogeno tonico ovarico para regimenes terapeuticos prolongados.

Country Status (29)

Country Link
EP (1) EP0769956B1 (es)
JP (1) JP3138477B2 (es)
CN (1) CN1137722C (es)
AP (1) AP775A (es)
AT (1) ATE190494T1 (es)
AU (1) AU691952B2 (es)
BG (1) BG63363B1 (es)
BR (1) BR9508718A (es)
CA (1) CA2195745C (es)
CY (1) CY2228B1 (es)
CZ (1) CZ291803B6 (es)
DE (1) DE69515666T2 (es)
DK (1) DK0769956T3 (es)
EE (1) EE03515B1 (es)
ES (1) ES2145286T3 (es)
FI (1) FI970244A (es)
GR (1) GR3033590T3 (es)
HU (1) HU218910B (es)
IL (1) IL114655A (es)
IS (1) IS4413A (es)
LV (1) LV11823B (es)
MX (1) MX9700574A (es)
NO (1) NO970257L (es)
NZ (1) NZ290554A (es)
OA (1) OA10730A (es)
PT (1) PT769956E (es)
RU (1) RU2181598C2 (es)
SK (1) SK282118B6 (es)
WO (1) WO1996003138A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8173592B1 (en) 1999-03-31 2012-05-08 Zentaris Ivf Gmbh Method for a programmed controlled ovarian stimulation protocol
UA73956C2 (en) * 1999-09-23 2005-10-17 Zentaris Gmbh Method for therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction due to extrauterine proliferation of endometrial tissue
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
GB0616111D0 (en) * 2006-06-16 2006-09-20 Ardana Bioscience Ltd Agents, methods and uses
EP2095818A1 (en) 2008-02-29 2009-09-02 AEterna Zentaris GmbH Use of LHRH antagonists at non-castrating doses
EP2307040B1 (en) * 2008-05-29 2015-09-09 Isr Immune System Regulation Ab Use of gnrh and sex hormones for treating viral disease, in particular hiv/aids
ES2753539T3 (es) * 2015-05-18 2020-04-13 Nerre Therapeutics Ltd Antagonista del receptor NK-1/NK-3 para el tratamiento de los sofocos
EP3560555A1 (en) * 2018-04-26 2019-10-30 LifeArc A composition for treating one or more estrogen related diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171835A (en) * 1988-10-21 1992-12-15 The Administrators Of The Tulane Educational Fund LHRH antagonists
US5169932A (en) * 1989-10-30 1992-12-08 The Salk Institute For Biological Studies Gnrh analogs
US5211952A (en) * 1991-04-12 1993-05-18 University Of Southern California Contraceptive methods and formulations for use therein
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5407955A (en) * 1994-02-18 1995-04-18 Eli Lilly And Company Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease

Also Published As

Publication number Publication date
CZ291803B6 (cs) 2003-06-18
CN1200674A (zh) 1998-12-02
IL114655A (en) 2005-08-31
CA2195745C (en) 2005-03-29
OA10730A (en) 2001-06-07
JPH10503203A (ja) 1998-03-24
BR9508718A (pt) 1997-12-30
HUT77127A (hu) 1998-03-02
WO1996003138A1 (en) 1996-02-08
HU9700046D0 (en) 1997-02-28
FI970244A0 (fi) 1997-01-21
CN1137722C (zh) 2004-02-11
AP9700913A0 (en) 1997-01-31
ES2145286T3 (es) 2000-07-01
CY2228B1 (en) 2003-04-18
EP0769956B1 (en) 2000-03-15
FI970244A (fi) 1997-01-21
DK0769956T3 (da) 2000-06-05
RU2181598C2 (ru) 2002-04-27
LV11823A (lv) 1997-08-20
IL114655A0 (en) 1995-11-27
DE69515666D1 (de) 2000-04-20
EP0769956A4 (en) 1999-03-10
GR3033590T3 (en) 2000-09-29
ATE190494T1 (de) 2000-04-15
JP3138477B2 (ja) 2001-02-26
BG63363B1 (bg) 2001-11-30
AU3132095A (en) 1996-02-22
PT769956E (pt) 2000-07-31
IS4413A (is) 1997-01-14
EE9700208A (et) 1998-02-16
BG101158A (en) 1997-09-30
SK7097A3 (en) 1997-11-05
EE03515B1 (et) 2001-10-15
AP775A (en) 1999-10-28
LV11823B (en) 1998-03-20
NZ290554A (en) 2000-08-25
NO970257D0 (no) 1997-01-21
HU218910B (hu) 2000-12-28
EP0769956A1 (en) 1997-05-02
AU691952B2 (en) 1998-05-28
DE69515666T2 (de) 2000-07-06
NO970257L (no) 1997-01-21
CA2195745A1 (en) 1996-02-08
SK282118B6 (sk) 2001-11-06
CZ15097A3 (en) 1997-11-12

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