DE69532927D1 - Cyclophasiges hormonverfahren das antiprogestin und progestin enthält - Google Patents
Cyclophasiges hormonverfahren das antiprogestin und progestin enthältInfo
- Publication number
- DE69532927D1 DE69532927D1 DE69532927T DE69532927T DE69532927D1 DE 69532927 D1 DE69532927 D1 DE 69532927D1 DE 69532927 T DE69532927 T DE 69532927T DE 69532927 T DE69532927 T DE 69532927T DE 69532927 D1 DE69532927 D1 DE 69532927D1
- Authority
- DE
- Germany
- Prior art keywords
- antiprogestin
- estrogen
- cyclophasic
- effective
- progestin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/359,159 US5521166A (en) | 1994-12-19 | 1994-12-19 | Antiprogestin cyclophasic hormonal regimen |
US359159 | 1994-12-19 | ||
PCT/US1995/016561 WO1996019227A1 (en) | 1994-12-19 | 1995-12-15 | Cyclophasic hormonal regimen containing antiprogestin and progestin |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69532927D1 true DE69532927D1 (de) | 2004-05-27 |
DE69532927T2 DE69532927T2 (de) | 2005-04-14 |
Family
ID=23412581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69532927T Expired - Lifetime DE69532927T2 (de) | 1994-12-19 | 1995-12-15 | Cyclophasiges hormonverfahren das antiprogestin und progestin enthält |
Country Status (11)
Country | Link |
---|---|
US (1) | US5521166A (de) |
EP (1) | EP0799043B1 (de) |
JP (1) | JPH10513152A (de) |
AT (1) | ATE264682T1 (de) |
AU (1) | AU711179B2 (de) |
CA (1) | CA2208007A1 (de) |
DE (1) | DE69532927T2 (de) |
DK (1) | DK0799043T3 (de) |
ES (1) | ES2219673T3 (de) |
PT (1) | PT799043E (de) |
WO (1) | WO1996019227A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6506390B2 (en) | 1996-06-25 | 2003-01-14 | Akzo Nobel | Progestogen-anti-progestogen regimens |
US20020012694A1 (en) * | 1997-09-17 | 2002-01-31 | Alfred J. Moo-Young | Transdermal administration of ment |
EP1030669A2 (de) | 1997-11-14 | 2000-08-30 | Akzo Nobel N.V. | Kontrazeptionsverfahren das antiprogestagen und progestagen enthält |
US6498154B1 (en) * | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
US6423699B1 (en) | 1999-05-04 | 2002-07-23 | American Home Products Corporation | Combination therapies using benzimidazolones |
US6444668B1 (en) | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
JP2002543155A (ja) * | 1999-05-04 | 2002-12-17 | ワイス | 抗プロゲスチン及びプロゲスチンを含有する避妊組成物 |
US6319912B1 (en) * | 1999-05-04 | 2001-11-20 | American Home Products Corporation | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides |
US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
US6355648B1 (en) * | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
US6329416B1 (en) | 1999-05-04 | 2001-12-11 | American Home Products Corporation | Combination regimens using 3,3-substituted indoline derivatives |
US6358947B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
AU4980100A (en) * | 1999-05-04 | 2000-11-17 | American Home Products Corporation | Compositions containing benzimidazolones and progestogens |
US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
US6399593B1 (en) | 1999-05-04 | 2002-06-04 | Wyeth | Cyclic regimens using cyclic urea and cyclic amide derivatives |
US6407101B1 (en) | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
US6462032B1 (en) * | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
US6380178B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Cyclic regimens using cyclocarbamate and cyclic amide derivatives |
US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
US6476079B1 (en) * | 1999-12-23 | 2002-11-05 | Leiras Oy | Devices for the delivery of drugs having antiprogestinic properties |
UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
WO2004010928A2 (en) * | 2002-07-25 | 2004-02-05 | Massachusetts Institute Of Technology | Steroid modulators in the treatment of peripheral nerve sheath tumors |
UA82851C2 (en) * | 2002-08-28 | 2008-05-26 | Estrogen replacement regimen in menopausal women | |
US8450379B2 (en) * | 2002-11-05 | 2013-05-28 | Corcept Therapeutics, Inc. | Methods for treating migraine |
US20060052354A1 (en) * | 2002-11-05 | 2006-03-09 | Corcept Therapeutics, Inc. | Methods for treating migraine |
US20060111318A1 (en) * | 2003-04-18 | 2006-05-25 | Advanced Medicine Research Institute | Agent for treating eye diseases |
US20070077269A1 (en) * | 2005-10-04 | 2007-04-05 | Woodward John R | Method of birth control and hormone regulation |
CA2673128C (en) * | 2006-10-24 | 2018-07-03 | Repros Therapeutics Inc. | Compositions and methods for suppressing endometrial proliferation |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
US4780461A (en) * | 1983-06-15 | 1988-10-25 | Schering Aktiengesellschaft | 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same |
DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
DE3708942A1 (de) * | 1987-03-18 | 1988-09-29 | Schering Ag | 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
DE19975054I2 (de) * | 1987-08-08 | 2000-04-13 | Akzo Nobel Nv | Kontrazeptives Implantat |
US5276022A (en) * | 1987-09-24 | 1994-01-04 | Jencap Research Ltd. | Hormone preparation and method |
US5108995A (en) * | 1987-09-24 | 1992-04-28 | Jencap Research Ltd. | Hormone preparation and method |
US5256421A (en) * | 1987-09-24 | 1993-10-26 | Jencap Research Ltd. | Hormone preparation and method |
DE3744054A1 (de) * | 1987-12-21 | 1989-06-29 | Schering Ag | Verwendung von antigestagenen zur herstellung von arzneimitteln |
MX9301121A (es) * | 1992-03-02 | 1993-09-01 | Schering Ag | Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina. |
WO1993021926A1 (en) * | 1992-05-06 | 1993-11-11 | Medical College Of Hampton Roads | Minimizing progestin associated breakthrough bleeding |
ZA935617B (en) * | 1992-08-14 | 1994-03-07 | Akzo Nv | Antiprogestogen containing contraceptives. |
-
1994
- 1994-12-19 US US08/359,159 patent/US5521166A/en not_active Expired - Lifetime
-
1995
- 1995-12-15 AU AU44730/96A patent/AU711179B2/en not_active Expired
- 1995-12-15 DE DE69532927T patent/DE69532927T2/de not_active Expired - Lifetime
- 1995-12-15 CA CA002208007A patent/CA2208007A1/en not_active Abandoned
- 1995-12-15 JP JP8519952A patent/JPH10513152A/ja active Pending
- 1995-12-15 DK DK95943476T patent/DK0799043T3/da active
- 1995-12-15 PT PT95943476T patent/PT799043E/pt unknown
- 1995-12-15 AT AT95943476T patent/ATE264682T1/de active
- 1995-12-15 EP EP95943476A patent/EP0799043B1/de not_active Expired - Lifetime
- 1995-12-15 ES ES95943476T patent/ES2219673T3/es not_active Expired - Lifetime
- 1995-12-15 WO PCT/US1995/016561 patent/WO1996019227A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DE69532927T2 (de) | 2005-04-14 |
JPH10513152A (ja) | 1998-12-15 |
EP0799043A1 (de) | 1997-10-08 |
CA2208007A1 (en) | 1996-06-27 |
ES2219673T3 (es) | 2004-12-01 |
ATE264682T1 (de) | 2004-05-15 |
WO1996019227A1 (en) | 1996-06-27 |
US5521166A (en) | 1996-05-28 |
AU4473096A (en) | 1996-07-10 |
EP0799043B1 (de) | 2004-04-21 |
AU711179B2 (en) | 1999-10-07 |
PT799043E (pt) | 2004-08-31 |
DK0799043T3 (da) | 2004-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN |