MX9400071A - ENDOTHELIN RECEPTOR ANTAGONISTS. - Google Patents

ENDOTHELIN RECEPTOR ANTAGONISTS.

Info

Publication number
MX9400071A
MX9400071A MX9400071A MX9400071A MX9400071A MX 9400071 A MX9400071 A MX 9400071A MX 9400071 A MX9400071 A MX 9400071A MX 9400071 A MX9400071 A MX 9400071A MX 9400071 A MX9400071 A MX 9400071A
Authority
MX
Mexico
Prior art keywords
receptor antagonists
endothelin receptor
endothelin
indole derivatives
novel indole
Prior art date
Application number
MX9400071A
Other languages
Spanish (es)
Inventor
John Duncan Elliott
Jack Dale Leber
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MX9400071A publication Critical patent/MX9400071A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describen nuevos derivados de indol, los cuales son antagonistas del receptor de endotelina.Novel indole derivatives are described, which are endothelin receptor antagonists.

MX9400071A 1992-12-22 1994-01-03 ENDOTHELIN RECEPTOR ANTAGONISTS. MX9400071A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99546692A 1992-12-22 1992-12-22

Publications (1)

Publication Number Publication Date
MX9400071A true MX9400071A (en) 1994-07-29

Family

ID=25541843

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9400071A MX9400071A (en) 1992-12-22 1994-01-03 ENDOTHELIN RECEPTOR ANTAGONISTS.

Country Status (7)

Country Link
EP (1) EP0676959A4 (en)
JP (1) JPH08504826A (en)
CN (1) CN1096513A (en)
AU (1) AU5873594A (en)
MX (1) MX9400071A (en)
WO (1) WO1994014434A1 (en)
ZA (1) ZA939516B (en)

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Also Published As

Publication number Publication date
EP0676959A4 (en) 1996-01-03
JPH08504826A (en) 1996-05-28
AU5873594A (en) 1994-07-19
WO1994014434A1 (en) 1994-07-07
EP0676959A1 (en) 1995-10-18
CN1096513A (en) 1994-12-21
ZA939516B (en) 1994-06-06

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