MX9306526A - Acido cis-3-(4,6-dihidroxicroman-3-ilmetil)benzoico. - Google Patents

Acido cis-3-(4,6-dihidroxicroman-3-ilmetil)benzoico.

Info

Publication number
MX9306526A
MX9306526A MX9306526A MX9306526A MX9306526A MX 9306526 A MX9306526 A MX 9306526A MX 9306526 A MX9306526 A MX 9306526A MX 9306526 A MX9306526 A MX 9306526A MX 9306526 A MX9306526 A MX 9306526A
Authority
MX
Mexico
Prior art keywords
cis
benzoic acid
ylmethyl
dihydroxychroman
preparation
Prior art date
Application number
MX9306526A
Other languages
English (en)
Inventor
Charles W Murtiashaw Iii
Brian C Vanderplas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9306526A publication Critical patent/MX9306526A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención trata de ácidos cis-3-(4, 6-dihidroxicroman-3-ilmetil)benzoico enantiómeros puros y de procedimientos para la preparación de tales compuestos. Los compuestos son productos intermedios útiles en la preparación de entiómeros ópticamente puros de sulfonamidas de cis-3-(6-arilmetil-oxi-4-hidroxicroman-3-ilmetil) anilinas que son útiles en el tratamiento de asma, artritis, psoriasis, úlceras, infarto de miocardio y enfermedades relacionadas. Más particularmente trata del ácido (3R-cis)-3-(4, 6-dihidroxicroman-3-ilmetil)-benzoico. También da cuenta de un procedimiento mejorado para la preparación del ácido cis-3-(4, 6-dihidroxicroman-3-ilmetil)benzoico.
MX9306526A 1992-10-21 1993-10-20 Acido cis-3-(4,6-dihidroxicroman-3-ilmetil)benzoico. MX9306526A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96433692A 1992-10-21 1992-10-21

Publications (1)

Publication Number Publication Date
MX9306526A true MX9306526A (es) 1994-04-29

Family

ID=25508434

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306526A MX9306526A (es) 1992-10-21 1993-10-20 Acido cis-3-(4,6-dihidroxicroman-3-ilmetil)benzoico.

Country Status (16)

Country Link
EP (1) EP0665839A1 (es)
JP (1) JPH07507811A (es)
KR (1) KR950704291A (es)
CN (1) CN1090577A (es)
AU (1) AU4650493A (es)
CA (1) CA2146005A1 (es)
CZ (1) CZ100895A3 (es)
FI (1) FI934624A (es)
HU (1) HUT65128A (es)
IL (1) IL107293A0 (es)
MX (1) MX9306526A (es)
MY (1) MY131378A (es)
NO (1) NO951507D0 (es)
PL (1) PL308473A1 (es)
WO (1) WO1994008986A1 (es)
ZA (1) ZA937737B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU713701B2 (en) * 1996-09-16 1999-12-09 Pfizer Inc. Processes and intermediates for preparing substituted chromanol derivatives
US6593492B1 (en) 1999-10-27 2003-07-15 Nobex Corporation Resolution of intermediates in the synthesis of substantially pure bicalutamide
MY128450A (en) 2000-05-24 2007-02-28 Upjohn Co 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6479692B1 (en) 2001-05-02 2002-11-12 Nobex Corporation Methods of synthesizing acylanilides including bicalutamide and derivatives thereof
EP2407462B1 (en) 2004-09-21 2014-07-30 Marshall Edwards, Inc. Substituted chroman derivatives, medicaments and use in therapy
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
CA2816319C (en) 2010-11-01 2020-06-30 Marshall Edwards, Inc. Isoflavonoid compounds and methods for the treatment of cancer
PT3253208T (pt) 2015-02-02 2021-06-17 The Spanish National Cancer Res Centre Terapêuticas de combinação para utilização no tratamento do cancro da mama

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059609A (en) * 1987-10-19 1991-10-22 Pfizer Inc. Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases

Also Published As

Publication number Publication date
EP0665839A1 (en) 1995-08-09
CN1090577A (zh) 1994-08-10
IL107293A0 (en) 1994-01-25
CZ100895A3 (en) 1995-10-18
PL308473A1 (en) 1995-08-07
FI934624A0 (fi) 1993-10-20
HU9302973D0 (en) 1993-12-28
NO951507L (no) 1995-04-20
FI934624A (fi) 1994-04-22
NO951507D0 (no) 1995-04-20
KR950704291A (ko) 1995-11-17
CA2146005A1 (en) 1994-04-28
HUT65128A (en) 1994-04-28
WO1994008986A1 (en) 1994-04-28
MY131378A (en) 2007-08-30
AU4650493A (en) 1994-05-09
JPH07507811A (ja) 1995-08-31
ZA937737B (en) 1995-04-19

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