MX9303706A - 9-amino-piridazino[4', 5': 3, 4]pirrolo-[2, 1-a]isoquinolinas y su empleo para la produccion de preparados farmaceuticos. - Google Patents
9-amino-piridazino[4', 5': 3, 4]pirrolo-[2, 1-a]isoquinolinas y su empleo para la produccion de preparados farmaceuticos.Info
- Publication number
- MX9303706A MX9303706A MX9303706A MX9303706A MX9303706A MX 9303706 A MX9303706 A MX 9303706A MX 9303706 A MX9303706 A MX 9303706A MX 9303706 A MX9303706 A MX 9303706A MX 9303706 A MX9303706 A MX 9303706A
- Authority
- MX
- Mexico
- Prior art keywords
- isoquinolines
- amino
- agents
- piridazino
- pirrolo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
El invento se refiere a la utilización de 9-aminopiridazino[4', 5':3, 4]pirrolo[2, 1-a]isoquinolinas de fórmula (I), así como de sus sales fisiológicamente compatibles con ácidos, bases y agentes formadores de complejos para la producción de agentes destinados al tratamiento de procesos inflamatorios crónicos, de la colitis ulcerosa y de la enfermedad de Crohn, así como de agentes con efecto antiproliferativo. Los significados de los sustituyentes R1 hasta R9 se indican en la memoria descriptiva. Además el invento se refiere a nuevos compuestos de fórmula general (I), que también están definidos en la memoria descriptiva y a su utilización como agentes protectores del cerebro.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19924220380 DE4220380A1 (de) | 1992-06-22 | 1992-06-22 | Verwendung von 9-Amino-pyridazino[4',5':3,4]pyrrolo-[2,1-a]isochinolinen zur Herstellung von Mitteln zur Behandlung der Colitis Ulcerosa und des Morbus Crohn |
DE19924220384 DE4220384A1 (de) | 1992-06-22 | 1992-06-22 | Verwendung von 9-Amino-pyridazino[4',5':3,4]pyrrolo-[2,1-a]isochinolinen zur Herstellung von Mitteln zur Behandlung chronisch inflammatorischer Prozesse |
DE4220361A DE4220361A1 (de) | 1992-06-22 | 1992-06-22 | Verwendung von 9-Amino-pyridazino[4',5':3,4]-pyrrolo-[2,1-a]isochinolinen zur Herstellung von Mitteln mit antiproliferativer Wirkung |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9303706A true MX9303706A (es) | 1994-01-31 |
Family
ID=27203872
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9303706A MX9303706A (es) | 1992-06-22 | 1993-06-21 | 9-amino-piridazino[4', 5': 3, 4]pirrolo-[2, 1-a]isoquinolinas y su empleo para la produccion de preparados farmaceuticos. |
Country Status (11)
Country | Link |
---|---|
US (2) | US5565452A (es) |
EP (1) | EP0647226B1 (es) |
JP (1) | JP3468520B2 (es) |
CN (1) | CN1082046A (es) |
AT (1) | ATE157665T1 (es) |
AU (1) | AU4327293A (es) |
CA (1) | CA2138791A1 (es) |
DE (1) | DE59307281D1 (es) |
IL (1) | IL106089A0 (es) |
MX (1) | MX9303706A (es) |
WO (1) | WO1994000451A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4343649A1 (de) * | 1993-12-21 | 1995-06-22 | Boehringer Ingelheim Kg | Neue Pyridazino[4',5':3,4]pyrrolo-[2,1-a]isochinoline und deren Verwendung für die Herstellung von pharmazeutischen Zubereitungen |
WO2003057696A1 (en) | 2002-01-07 | 2003-07-17 | Eisai Co. Ltd. | Deazapurines and uses thereof |
CN106995443B (zh) * | 2014-05-09 | 2022-01-11 | 皮梅拉股份有限公司 | 新组合物、用途和制备它们的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3401018A1 (de) * | 1984-01-13 | 1985-07-18 | Boehringer Ingelheim KG, 6507 Ingelheim | Verfahren zur herstellung von 5,6-dihydro-pyrrolo(2,1-a)isochinolinen |
US4764898A (en) * | 1984-12-13 | 1988-08-16 | Nippon Telegraph And Telephone Corporation | Vortex memory device |
DE3664772D1 (en) * | 1985-01-14 | 1989-09-07 | Boehringer Ingelheim Kg | 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use |
DE3619099A1 (de) * | 1986-06-06 | 1987-12-10 | Boehringer Ingelheim Kg | Verwendung von 12-amino-pyrridazino(4',5' : 3,4)pyrrolo-(2,1-a)-isochinolinen als cardio- und neuroprotektive mittel |
-
1993
- 1993-06-18 WO PCT/EP1993/001553 patent/WO1994000451A1/de active IP Right Grant
- 1993-06-18 AT AT93913008T patent/ATE157665T1/de not_active IP Right Cessation
- 1993-06-18 CA CA002138791A patent/CA2138791A1/en not_active Abandoned
- 1993-06-18 AU AU43272/93A patent/AU4327293A/en not_active Abandoned
- 1993-06-18 JP JP50201994A patent/JP3468520B2/ja not_active Expired - Fee Related
- 1993-06-18 DE DE59307281T patent/DE59307281D1/de not_active Expired - Fee Related
- 1993-06-18 EP EP93913008A patent/EP0647226B1/de not_active Expired - Lifetime
- 1993-06-21 MX MX9303706A patent/MX9303706A/es not_active IP Right Cessation
- 1993-06-21 IL IL106089A patent/IL106089A0/xx unknown
- 1993-06-22 CN CN93107617A patent/CN1082046A/zh active Pending
-
1994
- 1994-11-07 US US08/334,979 patent/US5565452A/en not_active Expired - Fee Related
-
1996
- 1996-05-17 US US08/649,550 patent/US5677304A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH07508016A (ja) | 1995-09-07 |
DE59307281D1 (de) | 1997-10-09 |
WO1994000451A1 (de) | 1994-01-06 |
CN1082046A (zh) | 1994-02-16 |
US5565452A (en) | 1996-10-15 |
JP3468520B2 (ja) | 2003-11-17 |
AU4327293A (en) | 1994-01-24 |
ATE157665T1 (de) | 1997-09-15 |
IL106089A0 (en) | 1993-10-20 |
CA2138791A1 (en) | 1994-01-06 |
US5677304A (en) | 1997-10-14 |
EP0647226B1 (de) | 1997-09-03 |
EP0647226A1 (de) | 1995-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |