MX9301535A - Material proteinaceo biologicamente activo aislado y purificado. - Google Patents

Material proteinaceo biologicamente activo aislado y purificado.

Info

Publication number
MX9301535A
MX9301535A MX9301535A MX9301535A MX9301535A MX 9301535 A MX9301535 A MX 9301535A MX 9301535 A MX9301535 A MX 9301535A MX 9301535 A MX9301535 A MX 9301535A MX 9301535 A MX9301535 A MX 9301535A
Authority
MX
Mexico
Prior art keywords
biologically active
purified
present
proteinaceous material
material isolated
Prior art date
Application number
MX9301535A
Other languages
English (en)
Inventor
Massimo Sabatini
Elzbieta Izbicka
Wilson Burgess
Gregg Crumley
Clarence C Morse
Timothy R Arnett
Gregory R Mundy
Gloria E Gutierrez
Ian R Garret
Original Assignee
Osteosa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteosa Inc filed Critical Osteosa Inc
Publication of MX9301535A publication Critical patent/MX9301535A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere al desarrollo de factores de crecimiento de huesos como terapéuticos para la prevención y tratamiento de condiciones patológicas que implican el tejido óseo. La presente invención provee factores proteináceos biológicamente activos que comprenden polipéptidos que contienen la secuencia de aminoácidos M-A-G-L-G-D-E-F-G-D, (X) F E T L F G A/V E D V I / D A L Q F V C G D, o A-Y-I-P-I-E-T-L-E-G-I/G-E-L-V-D/Q-T-G/L-Q-F o fragmentos biológicamente activos o análogos de secuencia de los mismos. Entre las propiedades biológicas de los materiales proteináceos de la presente invención están la capacidad de promover el crecimiento y/o diferenciación de células osteoblásticas.
MX9301535A 1992-03-18 1993-03-18 Material proteinaceo biologicamente activo aislado y purificado. MX9301535A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85541592A 1992-03-18 1992-03-18

Publications (1)

Publication Number Publication Date
MX9301535A true MX9301535A (es) 1994-03-31

Family

ID=25321219

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9301535A MX9301535A (es) 1992-03-18 1993-03-18 Material proteinaceo biologicamente activo aislado y purificado.

Country Status (7)

Country Link
US (1) US5408041A (es)
EP (1) EP0728142A4 (es)
JP (1) JPH07505161A (es)
AU (1) AU3921993A (es)
CA (1) CA2132219A1 (es)
MX (1) MX9301535A (es)
WO (1) WO1993019085A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712249A (en) * 1994-09-08 1998-01-27 Ciba-Geigy Corporation Use of insulin-like growth factors I and II for inhibition of inflammatory response
US6124262A (en) * 1995-03-17 2000-09-26 The Regents Of The University Of California Compositions and methods for reducing adhesiveness of defective red blood cells
WO1997024434A1 (en) * 1995-12-29 1997-07-10 Alg Company Expansion of bone marrow stromal cells
DE69523956T2 (de) * 1995-12-29 2002-07-18 Alg Company, Marlborough Vermehrung von knochenmarksstützzellen
CA2227312C (en) * 1997-06-26 2002-11-19 Jeong S. Sim Nutraceutical antler powder and a method of producing same
US6093421A (en) * 1999-08-31 2000-07-25 Biotics Research Corporation Maca and antler for augmenting testosterone levels
KR100397220B1 (ko) * 2000-07-13 2003-09-13 전길자 녹용으로부터 추출된 골형성 촉진 물질 및 그의 추출방법
US20050153359A1 (en) * 2002-03-11 2005-07-14 Schaefer Allan L. Method for the evaluation of velvet antler
NZ526157A (en) * 2003-05-27 2006-01-27 Velvet Antler Res New Zealand Method for the extraction of deer antler and use of the extract therefrom
WO2011034447A1 (en) * 2009-09-15 2011-03-24 Andeer (Nz) Limited Active composition from deer antler and methods of use
EA201290577A1 (ru) 2010-01-26 2013-06-28 Стем Селз Спин С.А. Клеточный гомогенат из стволовых клеток, полученных из растущих рогов оленя, способ его получения и применения
CN114569634B (zh) * 2022-03-14 2024-03-12 广州医科大学附属口腔医院 鹿茸间充质干细胞条件培养基在牙周炎药物中的用途
CN114720592B (zh) * 2022-03-25 2023-04-18 山东省食品药品检验研究院 一种含有鹿源成分的中药制剂中掺伪的筛查方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
US5108753A (en) * 1988-04-08 1992-04-28 Creative Biomolecules Osteogenic devices
US5106626A (en) * 1988-10-11 1992-04-21 International Genetic Engineering, Inc. Osteogenic factors

Also Published As

Publication number Publication date
JPH07505161A (ja) 1995-06-08
WO1993019085A1 (en) 1993-09-30
AU3921993A (en) 1993-10-21
EP0728142A4 (en) 1997-05-02
US5408041A (en) 1995-04-18
EP0728142A1 (en) 1996-08-28
CA2132219A1 (en) 1993-09-30

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