MX9205893A - Inhibidores de acat de sulfonil urea y carbamato. - Google Patents

Inhibidores de acat de sulfonil urea y carbamato.

Info

Publication number
MX9205893A
MX9205893A MX9205893A MX9205893A MX9205893A MX 9205893 A MX9205893 A MX 9205893A MX 9205893 A MX9205893 A MX 9205893A MX 9205893 A MX9205893 A MX 9205893A MX 9205893 A MX9205893 A MX 9205893A
Authority
MX
Mexico
Prior art keywords
sulfonil
carbamate
urea
acat inhibitors
acat
Prior art date
Application number
MX9205893A
Other languages
English (en)
Inventor
Joseph Armand Picard
William Howard Roark
Bruce David Roth
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MX9205893A publication Critical patent/MX9205893A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/53—X and Y not being nitrogen atoms, e.g. N-sulfonylcarbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/55—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX9205893A 1991-10-15 1992-10-14 Inhibidores de acat de sulfonil urea y carbamato. MX9205893A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/776,112 US5254589A (en) 1991-10-15 1991-10-15 Sulfonyl urea and carbamate ACAT inhibitors

Publications (1)

Publication Number Publication Date
MX9205893A true MX9205893A (es) 1993-04-01

Family

ID=25106489

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9205893A MX9205893A (es) 1991-10-15 1992-10-14 Inhibidores de acat de sulfonil urea y carbamato.

Country Status (5)

Country Link
US (2) US5254589A (es)
AU (1) AU2869792A (es)
MX (1) MX9205893A (es)
PT (1) PT100960A (es)
WO (1) WO1993008161A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254589A (en) * 1991-10-15 1993-10-19 Warner-Lambert Company Sulfonyl urea and carbamate ACAT inhibitors
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
EP0701905B1 (en) * 1994-09-14 1998-12-23 Oji Paper Co., Ltd. Thermosensitive reversible colordeveloping and disappearing agent
ATE242208T1 (de) * 1997-01-29 2003-06-15 Pfizer Sulfonylharnstoff-derivate und ihre verwendung in der kontrolle der interleukin-1-aktivität
EP1270565B1 (en) * 1997-01-29 2004-06-30 Pfizer Inc. 4-Substituted furan-2-sulfonamide and its use in the preparation of sulfonyl urea derivatives
US6093744A (en) * 1997-04-21 2000-07-25 Warner-Lambert Company N-acyl sulfamic acid esters useful as hypocholesterolemic agents
US7304093B2 (en) * 2000-10-11 2007-12-04 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
CN1479721A (zh) 2000-10-11 2004-03-03 ͨ��ҽ�ƹ�˾ 用于胆固醇治疗和相关应用的亚砜和双亚砜化合物和组合物
US20040122091A1 (en) * 2000-10-11 2004-06-24 Esperion Therapeutics, Inc. Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
EP1363879A2 (en) 2000-10-11 2003-11-26 Esperion Therapeutics Inc. Sulfide and disulfide compounds and compositions for cholesterol management and related uses
IL155215A0 (en) 2000-10-11 2003-11-23 Esperion Therapeutics Inc Ether compounds and compositions for cholesterol management and related uses
US6699910B2 (en) 2000-10-11 2004-03-02 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
CA2369967A1 (en) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methods of treating nuclear factor-kappa b mediated diseases and disorders
US20040204502A1 (en) * 2001-10-11 2004-10-14 Dasseux Jean-Louis Henri Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
US20050020694A1 (en) * 2001-10-11 2005-01-27 Dasseux Jean-Louis Henri Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US20040192771A1 (en) * 2001-10-11 2004-09-30 Dasseux Jean-Louis Henri Ether compounds and compositions for cholesterol management and related uses
MXPA04009831A (es) * 2002-04-10 2004-12-07 Esperion Therapeutics Inc Imitaciones de la coenzima-a de acilo, composiciones de las mismas y metodos de manejo del colesterol y usos relacionados.
AU2004207444B2 (en) * 2003-01-17 2008-07-31 Merck & Co., Inc. N-cyclohexylaminocarbonyl benzenesulfonamide derivatives
SI2404890T1 (sl) * 2003-01-23 2017-12-29 Esperion Therapeutics Inc. Hidroksilne spojine in sestavki za uravnavanje holesterola in sorodne uporabe
EP1701931B1 (en) 2003-12-24 2018-10-10 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
MX2017011499A (es) 2015-03-13 2018-03-26 Esperion Therapeutics Inc Combinaciones de dosis fija y formulaciones que comprenden ácido 8-hidroxi-2,2,14,14 tetrametilpentadecanodioico (etc1002) y ezetimiba y métodos para tratar o reducir el riesgo de enfermedad cardiovascular.
MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
US11518739B2 (en) * 2017-08-15 2022-12-06 Inflazome Limited Sulfonamide carboxamide compounds
KR20220024816A (ko) 2019-06-21 2022-03-03 에스페리온 테라피유틱스 인코포레이티드 벰페도산 및 그의 조성물을 제조하는 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1075588B (de) * 1960-02-18 Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Bruning Frankfurt/M Verfahren zur Herstellung von Sulfonylharnstoffen
CA613312A (en) * 1961-01-24 Aumuller Walter N-sulfonyl-n'-acyl-ureas and process for their manufacture
US2975212A (en) * 1956-05-26 1961-03-14 Hoechst Ag New sulfonyl-ureas and process for their preparation
NL219667A (es) * 1956-08-10 1964-03-16
GB815885A (en) * 1956-08-10 1959-07-01 Hoechst Ag Sulphonyl-ureas and a process for their manufacture
AT204563B (de) * 1958-04-05 1959-07-25 Anton Von Waldheim Chem Pharm Verfahren zur Herstellung von neuen Sulfonylharnstoffen
US3013072A (en) * 1958-09-02 1961-12-12 Pfizer & Co C Novel process for the production of sulfonylureas
GB909318A (en) * 1960-08-22 1962-10-31 Ferrania Spa Improvements in the preparation of photographic colour images by colour development
US4013706A (en) * 1973-11-14 1977-03-22 Sucreries Du Soissonnais Et Compagnie Sucriere Derivatives of substituted urea, acyl ureas, and sulphonyl ureas, and a process for producing the same
US3983107A (en) * 1973-12-05 1976-09-28 Pfizer Inc. Hypolipidemic alkenesulfonamides
FR2501681A1 (fr) * 1981-03-12 1982-09-17 Ciba Geigy Ag Nouvelles acyl- et sulfonyl-urees, leur application en tant qu'agents microbicides
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
ATE61574T1 (de) * 1987-07-02 1991-03-15 Warner Lambert Co N-((2,6-disubstituierte)-phenyl>-harnstoff und - carbamat-inhibitoren der acyl-coenzym a:cholesterol-acyltransferase.
US5216026A (en) * 1990-07-17 1993-06-01 Eli Lilly And Company Antitumor compositions and methods of treatment
US5254589A (en) * 1991-10-15 1993-10-19 Warner-Lambert Company Sulfonyl urea and carbamate ACAT inhibitors

Also Published As

Publication number Publication date
WO1993008161A1 (en) 1993-04-29
US5254589A (en) 1993-10-19
AU2869792A (en) 1993-05-21
PT100960A (pt) 1993-11-30
US5981595A (en) 1999-11-09

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