MX9102830A - Conversion sintetica de briostatin 2 en briostatin 1. - Google Patents

Conversion sintetica de briostatin 2 en briostatin 1.

Info

Publication number
MX9102830A
MX9102830A MX9102830A MX9102830A MX9102830A MX 9102830 A MX9102830 A MX 9102830A MX 9102830 A MX9102830 A MX 9102830A MX 9102830 A MX9102830 A MX 9102830A MX 9102830 A MX9102830 A MX 9102830A
Authority
MX
Mexico
Prior art keywords
briostatin
synthetic conversion
bryostatin
synthetic
conversion
Prior art date
Application number
MX9102830A
Other languages
English (en)
Inventor
George R Pettit
Original Assignee
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arizona filed Critical Univ Arizona
Publication of MX9102830A publication Critical patent/MX9102830A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Auxiliary Devices For Music (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Plant Substances (AREA)
MX9102830A 1990-12-31 1991-12-27 Conversion sintetica de briostatin 2 en briostatin 1. MX9102830A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/636,212 US5072004A (en) 1990-12-31 1990-12-31 Synthetic conversion of bryostatin 2 into bryostatin 1

Publications (1)

Publication Number Publication Date
MX9102830A true MX9102830A (es) 1992-06-01

Family

ID=24550938

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9102830A MX9102830A (es) 1990-12-31 1991-12-27 Conversion sintetica de briostatin 2 en briostatin 1.

Country Status (10)

Country Link
US (1) US5072004A (es)
EP (1) EP0496160B1 (es)
JP (1) JP3225318B2 (es)
AT (1) ATE152724T1 (es)
CA (1) CA2057441C (es)
DE (1) DE69126011T2 (es)
DK (1) DK0496160T3 (es)
ES (1) ES2103788T3 (es)
GR (1) GR3023990T3 (es)
MX (1) MX9102830A (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7256286B2 (en) * 1999-11-30 2007-08-14 The Board Of Trustees Of The Leland Stanford Junior University Bryostatin analogues, synthetic methods and uses
WO2002087423A2 (en) * 2001-05-02 2002-11-07 Blanchette Rockefeller Neurosciences Institute Carbonic anhydrase activators for enhancing learning and memory
US20050065205A1 (en) * 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
US20080004332A1 (en) * 2002-03-07 2008-01-03 Alkon Daniel L Methods for alzheimer's disease treatment and cognitive enhancement
TW201206425A (en) * 2004-05-18 2012-02-16 Brni Neurosciences Inst Treatment of depressive disorders
KR20130122630A (ko) 2005-07-29 2013-11-07 블랜체트 록펠러 뉴로사이언시즈 인스티튜트 단독의 또는 ｐｋｃ 억제제와 배합된 ｐｋｃ 활성화제의 장기 기억 향상을 위한 용도
US7754465B2 (en) * 2006-04-27 2010-07-13 James A Papp Decontamination of biological agents
EP2073801A1 (en) 2006-07-28 2009-07-01 Blanchette Rockefeller Neurosciences Institute Methods of stimulating cellular growth, synaptic remodeling and consolidation of long-term memory
ES2548766T3 (es) 2007-02-09 2015-10-20 Blanchette Rockefeller Neurosciences Institute Efectos terapéuticos de las briostatinas, briólogos y otras sustancias relacionadas en alteraciones de la memoria inducidas por trauma craneal y por lesiones cerebrales
CA3006091A1 (en) 2007-02-09 2008-08-21 Blanchette Rockefeller Neurosciences Institute Therapeutic effects of bryostatins, bryologs, and other related substances on ischemia/stroke-induced memory impairment and brain injury
CA2804789A1 (en) 2010-07-08 2012-01-12 Daniel L. Alkon Pkc activators and anticoagulant in regimen for treating stroke
JP6062362B2 (ja) 2010-08-19 2017-01-18 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート Ｐｋｃ活性化剤を使用した、異常な樹状突起棘に関連した認知障害の治療
EP2776018B1 (en) 2011-11-13 2021-08-25 Cognitive Research Enterprises, Inc. Pkc activators and combinations thereof
WO2016130969A1 (en) 2015-02-13 2016-08-18 George Robert Pettit Silstatin compounds
JP2018521113A (ja) 2015-05-11 2018-08-02 アルコン、ダニエル・エル． ＡｐｏＥ４対立遺伝子の存在を決定した後のＰＫＣ活性化因子を使用した神経変性状態の治療
WO2019094709A1 (en) 2017-11-09 2019-05-16 Pettit George R Betulastatin compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560774A (en) * 1982-11-17 1985-12-24 Arizona State University Macrocyclic lactones
US4611066A (en) * 1984-08-10 1986-09-09 Arizona State University Bryostatins 4 to 8
US4833257A (en) * 1986-07-28 1989-05-23 Arizona Board Of Regents Compositions of matter and methods of using same

Also Published As

Publication number Publication date
ES2103788T3 (es) 1997-10-01
DK0496160T3 (da) 1997-07-28
JPH0867683A (ja) 1996-03-12
CA2057441A1 (en) 1992-07-01
GR3023990T3 (en) 1997-10-31
EP0496160B1 (en) 1997-05-07
CA2057441C (en) 2002-06-11
DE69126011D1 (de) 1997-06-12
US5072004A (en) 1991-12-10
EP0496160A1 (en) 1992-07-29
DE69126011T2 (de) 1997-09-25
ATE152724T1 (de) 1997-05-15
JP3225318B2 (ja) 2001-11-05

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees