MX388028B - Suministro de antioxidantes bioactivos, nanoencapsulados. - Google Patents

Suministro de antioxidantes bioactivos, nanoencapsulados.

Info

Publication number
MX388028B
MX388028B MX2017001903A MX2017001903A MX388028B MX 388028 B MX388028 B MX 388028B MX 2017001903 A MX2017001903 A MX 2017001903A MX 2017001903 A MX2017001903 A MX 2017001903A MX 388028 B MX388028 B MX 388028B
Authority
MX
Mexico
Prior art keywords
antioxidant
nanoparticles
bioactive
compositions
methods
Prior art date
Application number
MX2017001903A
Other languages
English (en)
Spanish (es)
Other versions
MX2017001903A (es
Inventor
Carlos E Astete
Christina M Sabliov
Ede Bodoki
Elena Dinte
Oliviu Vostinaru
Ovidiu Ciprian Samoila
Original Assignee
Univ Louisiana State
Iuliu Hatieganu Univ Of Medicine And Pharmacy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Louisiana State, Iuliu Hatieganu Univ Of Medicine And Pharmacy filed Critical Univ Louisiana State
Publication of MX2017001903A publication Critical patent/MX2017001903A/es
Publication of MX388028B publication Critical patent/MX388028B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2017001903A 2014-08-11 2015-08-10 Suministro de antioxidantes bioactivos, nanoencapsulados. MX388028B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462035683P 2014-08-11 2014-08-11
US201562172455P 2015-06-08 2015-06-08
PCT/US2015/044483 WO2016025394A2 (en) 2014-08-11 2015-08-10 Delivery of bioactive, nanoencapsulated antioxidants

Publications (2)

Publication Number Publication Date
MX2017001903A MX2017001903A (es) 2017-09-26
MX388028B true MX388028B (es) 2025-03-19

Family

ID=55304745

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001903A MX388028B (es) 2014-08-11 2015-08-10 Suministro de antioxidantes bioactivos, nanoencapsulados.

Country Status (12)

Country Link
US (2) US10292943B2 (enExample)
EP (1) EP3179988A4 (enExample)
JP (1) JP6668327B2 (enExample)
KR (1) KR102218883B1 (enExample)
AP (1) AP2017009684A0 (enExample)
AU (1) AU2015301945B2 (enExample)
BR (1) BR112017002580A2 (enExample)
CA (1) CA2992879C (enExample)
EA (1) EA035620B1 (enExample)
MX (1) MX388028B (enExample)
WO (1) WO2016025394A2 (enExample)
ZA (1) ZA201700987B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2017009684A0 (enExample) * 2014-08-11 2017-01-31
WO2019148140A2 (en) * 2018-01-26 2019-08-01 Wu Joseph C Implantable biomaterials that enhance stem cell survival and function
WO2020249825A1 (en) * 2019-06-14 2020-12-17 Folium Biosciences Europe B.V. Method for micro-encapsulation of natural ingredients by means of contacting with supercritical gas
IL297592A (en) * 2020-05-11 2022-12-01 Op2Lysis A slow release formulation of a plasmogen activator for use in the treatment of thrombosis or hemorrhagic disease
US11298321B1 (en) 2021-07-12 2022-04-12 King Abdulaziz University Methods for treating metabolic disorder
US11253481B1 (en) 2021-07-12 2022-02-22 King Abdulaziz University Self-nanoemulsifying 3D-printed tablet composition and method of use thereof
KR102824097B1 (ko) 2022-12-07 2025-06-24 주식회사 엘지생활건강 바이오틴이 담지된 나노파티클 및 이의 제조 방법, 및 이의 용도
WO2025106389A1 (en) * 2023-11-13 2025-05-22 Universitatea De Medicină Şi Farmacie Iluiu Haţieganu New forms of lutein and their uses

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0386960A3 (en) 1989-03-07 1991-10-23 American Cyanamid Company Pharmaceutical compositions useful as drug delivery vehicles and/or as wound dressings
US6573299B1 (en) * 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
US6703039B2 (en) * 2000-12-06 2004-03-09 Bausch & Lomb Incorporated Reversible gelling system for ocular drug delivery
DE10141018A1 (de) * 2001-08-22 2003-03-13 Eth Zuerich Eidgenoessische Te Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
US20040009212A1 (en) 2002-01-30 2004-01-15 Pharma Power Biotec Co. Ltd. Mucoadhesive thermoresponsive medicament-carrier composition
ATE424795T1 (de) 2002-06-05 2009-03-15 Univ Florida Ophthalmisches arzneimittelabgabesystem
JP2009515821A (ja) * 2005-10-16 2009-04-16 リコレッド リミテッド 眼疾患を治療するための組成物
WO2008137831A1 (en) * 2007-05-07 2008-11-13 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Water-soluble nanoparticles containing water-insoluble compounds
PT2594140T (pt) 2010-07-16 2019-06-11 Centro Nac De Tecnologia Y Seguridad Alimentaria Laboratorio Dei Ebro Nanopartículas para encapsulamento de compostos, sua produção e utilizações
MX2013002115A (es) 2010-09-03 2013-06-28 Novagali Pharma Sa Una emulsion del tipo de agua en aceite para tratar una enfermedad de los ojos.
EP2678007A4 (en) * 2011-02-25 2015-08-12 Univ South Dakota PROTEIN NANOTRIER FOR TOPICAL ADMINISTRATION
US20120231072A1 (en) * 2011-03-11 2012-09-13 Chemisches Institut Schaefer Ag Thermo-responsive hydrogel compositions
CN103845278B (zh) * 2012-11-30 2016-06-22 沈阳药科大学 一种叶黄素眼用纳米乳-温度敏感型原位凝胶及其制备方法
AP2017009684A0 (enExample) * 2014-08-11 2017-01-31

Also Published As

Publication number Publication date
MX2017001903A (es) 2017-09-26
AP2017009684A0 (enExample) 2017-01-31
US20170216221A1 (en) 2017-08-03
US10952974B2 (en) 2021-03-23
BR112017002580A2 (pt) 2018-03-27
AU2015301945A1 (en) 2017-03-09
KR102218883B1 (ko) 2021-02-23
JP6668327B2 (ja) 2020-03-18
ZA201700987B (en) 2019-05-29
US20190254987A1 (en) 2019-08-22
WO2016025394A2 (en) 2016-02-18
EP3179988A2 (en) 2017-06-21
AU2015301945B2 (en) 2020-05-14
EA201790361A1 (ru) 2017-06-30
KR20170097601A (ko) 2017-08-28
JP2017523983A (ja) 2017-08-24
WO2016025394A3 (en) 2016-05-19
EP3179988A4 (en) 2018-11-14
US10292943B2 (en) 2019-05-21
CA2992879A1 (en) 2016-02-18
CA2992879C (en) 2022-10-25
EA035620B1 (ru) 2020-07-16

Similar Documents

Publication Publication Date Title
MX388028B (es) Suministro de antioxidantes bioactivos, nanoencapsulados.
HK1243942A1 (zh) 舒尼替尼制剂及其在治疗青光眼中的使用方法
HK1218850A1 (zh) 持续药物递送植入物
EP4279064A3 (en) Drug delivery from hydrogels
BR112015006929A2 (pt) sistemas de distribuição de droga biodegradável para liberação sustentada de proteínas
HK1249140A1 (zh) 用於调节tmprss6表达的化合物和方法
HK1252771A1 (zh) 用於治疗眼部病状的玻璃体内药物递送系统
PH12017502155A1 (en) Formation of cyclosporin a/cyclodextrin nanoparticles
WO2011084366A3 (en) Compositions and drug delivery systems for intraocular delivery of sirna molecules, their use for treating conditions
WO2014143754A3 (en) Prostamide-containing intraocular implant
MX2016012846A (es) Preparacion de microesferas de plga cargadas de peptido con caracteristicas de liberacion controlada.
EP3176163A4 (en) Novel indene derivative, preparation method for same, and pharmaceutical composition, for preventing or treating retinal diseases, containing same as active ingredient
PT3678673T (pt) Composições e processos para aministração dirigida, expressão e modulação de ácidos robonucleicos codificantes num tecido
MX2022002306A (es) Metodos de tratamiento de enfermedades oculares con un implante para la administracion sostenida de farmacos.
ZA201701303B (en) Ocular formulations for drug-delivery and protection of the anterior segment of the eye
EP3167893A4 (en) Pharmaceutical composition containing spirulina maxima extract as active ingredient for preventing and treating retinal diseases
MX2019003365A (es) Composiciones de ester de colina de acido lipoico y metodos para estabilizar en productos farmacologicos farmaceuticamente relevantes.
MX2020012011A (es) Conjugados y derivados de prostaglandina para tratar el glaucoma y la hipertension ocular.
MX385405B (es) Composición inyectable en el vítreo de un ojo que comprende un inhibidor de cinasa y el uso de la misma para tratar una enfermedad ocular.
MX2016009600A (es) Agentes para utilizarse en el tratamiento de la inflamacion de retina.
SG11202004940VA (en) Ophthalmic topical composition comprising dobesilic acid for treating diseases of the posterior segment of the eye
WO2019022482A3 (ko) 황칠나무 추출물을 유효성분으로 포함하는 섬유화 질환의 예방 또는 치료용 조성물
HK1238134A1 (en) Delivery of bioactive, nanoencapsulated antioxidants
UY33562A (es) Agonistas de receptores de bradicinina y su utilización para el tratamiento de la hipertensión ocular y el glaucoma
NZ734845A (en) Use of short synthetic peptide for the treatment and/or prophylaxis of dry eye disease