MX387235B - Derivados de pirazolopiridina y su uso en terapia - Google Patents

Derivados de pirazolopiridina y su uso en terapia

Info

Publication number
MX387235B
MX387235B MX2017002816A MX2017002816A MX387235B MX 387235 B MX387235 B MX 387235B MX 2017002816 A MX2017002816 A MX 2017002816A MX 2017002816 A MX2017002816 A MX 2017002816A MX 387235 B MX387235 B MX 387235B
Authority
MX
Mexico
Prior art keywords
pyrazolopyridine derivatives
therapy
pyrazolopyridine
derivatives
parasite
Prior art date
Application number
MX2017002816A
Other languages
English (en)
Other versions
MX2017002816A (es
Inventor
Grzegorz Popowicz
Leonidas Emmanouilidis
Maciej Dawidowski
Michael Sattler
Ralf Erdmann
Vishal Kalel
Wolfgang Schliebs
Original Assignee
Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh filed Critical Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh
Publication of MX2017002816A publication Critical patent/MX2017002816A/es
Publication of MX387235B publication Critical patent/MX387235B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invencion se refiere a derivados de pirazolopiridina, que son utiles como medicamentos, composiciones farmaceuticas que comprenden uno o mas de los derivados de pirazolopiridina, y el uso de uno o mas de los derivados de pirazolopiridina en metodos para tratar y/o prevenir una enfermedad provocada o mediada por un parasito de la familia Trypanosomatidae.
MX2017002816A 2014-09-08 2015-09-08 Derivados de pirazolopiridina y su uso en terapia MX387235B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14183991.0A EP2993174A1 (en) 2014-09-08 2014-09-08 Pyrazolopyridine derivatives and their use in therapy
PCT/EP2015/070513 WO2016038045A1 (en) 2014-09-08 2015-09-08 Pyrazolopyridine derivatives and their use in therapy

Publications (2)

Publication Number Publication Date
MX2017002816A MX2017002816A (es) 2017-08-02
MX387235B true MX387235B (es) 2025-03-18

Family

ID=51485526

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017002816A MX387235B (es) 2014-09-08 2015-09-08 Derivados de pirazolopiridina y su uso en terapia

Country Status (5)

Country Link
US (2) US9840504B2 (es)
EP (2) EP2993174A1 (es)
BR (1) BR112017003346B8 (es)
MX (1) MX387235B (es)
WO (1) WO2016038045A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109476663B (zh) * 2016-05-24 2021-11-09 基因泰克公司 用于治疗癌症的吡唑并吡啶衍生物
ES2817426T3 (es) * 2016-06-29 2021-04-07 Novira Therapeutics Inc Derivados de oxadiazepinona y su uso en el tratamiento de infecciones por hepatitis B
MA45550A (fr) * 2016-06-29 2019-05-08 Novira Therapeutics Inc Dérivés de diazépinone et leur utilisation dans le traitement des infections par l'hépatite b
JOP20190060A1 (ar) 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1
US11312723B2 (en) 2017-11-29 2022-04-26 The Rockefeller University Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseases
JP7461104B2 (ja) * 2017-11-29 2024-04-03 中外製薬株式会社 Ｇｌｐ－１受容体アゴニスト作用を持つピラゾロピリジン誘導体を含有する医薬組成物
GB201720064D0 (en) * 2017-12-01 2018-01-17 Univ Edinburgh Compounds
US20220323455A1 (en) * 2019-05-28 2022-10-13 Janssen Sciences Ireland Unlimited Company Fused heterocyclic derivatives as antiviral agents
KR20220012913A (ko) * 2019-05-28 2022-02-04 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 융합 복소환 유도체
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers
FI4097099T3 (fi) 2020-02-07 2024-07-30 Gasherbrum Bio Inc Heterosyklisiä glp-1-agonisteja
CN113264931B (zh) * 2020-02-17 2022-06-07 成都先导药物开发股份有限公司 一种1,4,6,7-四氢-5H-吡唑并[4,3-c]吡啶衍生物的制备方法
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
UY39550A (es) * 2020-12-02 2022-05-31 Janssen Sciences Ireland Unlimited Co Derivados heterocíclicos condensados
JP7728367B2 (ja) 2021-06-14 2025-08-22 スコーピオン・セラピューティクス・インコーポレイテッド がんを処置するために使用され得る尿素誘導体
AU2024222719A1 (en) 2023-02-16 2025-08-21 Gasherbrum Bio, Inc. Heterocyclic glp-1 agonists
WO2026001866A1 (zh) * 2024-06-24 2026-01-02 联邦生物科技(珠海横琴)有限公司 一种glp-1受体激动剂及其应用

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US4475196A (en) 1981-03-06 1984-10-02 Zor Clair G Instrument for locating faults in aircraft passenger reading light and attendant call control system
US4447233A (en) 1981-04-10 1984-05-08 Parker-Hannifin Corporation Medication infusion pump
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US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4447224A (en) 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus
US4487603A (en) 1982-11-26 1984-12-11 Cordis Corporation Implantable microinfusion pump system
US4486194A (en) 1983-06-08 1984-12-04 James Ferrara Therapeutic device for administering medicaments through the skin
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US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
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AU2006279548A1 (en) * 2005-08-16 2007-02-22 Amgen, Inc. Phosphodiesterase 10 inhibitors

Also Published As

Publication number Publication date
WO2016038045A1 (en) 2016-03-17
EP3191484A1 (en) 2017-07-19
US10138242B2 (en) 2018-11-27
MX2017002816A (es) 2017-08-02
US20180186789A1 (en) 2018-07-05
EP3191484B1 (en) 2024-06-12
US20170247375A1 (en) 2017-08-31
BR112017003346B8 (pt) 2023-11-28
BR112017003346B1 (pt) 2023-11-07
BR112017003346A2 (pt) 2018-11-06
US9840504B2 (en) 2017-12-12
EP2993174A1 (en) 2016-03-09

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