MX384378B - Dosificación terapéutica de una neurorregulina o una subsecuencia de la misma para el tratamiento o profilaxis de la falla cardiaca. - Google Patents

Dosificación terapéutica de una neurorregulina o una subsecuencia de la misma para el tratamiento o profilaxis de la falla cardiaca.

Info

Publication number
MX384378B
MX384378B MX2015001826A MX2015001826A MX384378B MX 384378 B MX384378 B MX 384378B MX 2015001826 A MX2015001826 A MX 2015001826A MX 2015001826 A MX2015001826 A MX 2015001826A MX 384378 B MX384378 B MX 384378B
Authority
MX
Mexico
Prior art keywords
treatment
heart failure
subsecence
neuroregulin
prophylaxis
Prior art date
Application number
MX2015001826A
Other languages
English (en)
Spanish (es)
Inventor
Anthony Caggiano
Anindita Ganguly
Jennifer Iaci
Tom Parry
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of MX384378B publication Critical patent/MX384378B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1883Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MX2015001826A 2008-07-17 2009-07-17 Dosificación terapéutica de una neurorregulina o una subsecuencia de la misma para el tratamiento o profilaxis de la falla cardiaca. MX384378B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13517108P 2008-07-17 2008-07-17
PCT/US2009/004130 WO2010030317A2 (en) 2008-07-17 2009-07-17 Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure

Publications (1)

Publication Number Publication Date
MX384378B true MX384378B (es) 2025-03-14

Family

ID=42005671

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011000696A MX2011000696A (es) 2008-07-17 2009-07-17 Dosificacion terapeutica de una neurregulina o una subsecuencia de la misma para el tratamiento o la profilaxis de insuficiencia cardiaca.
MX2015001826A MX384378B (es) 2008-07-17 2009-07-17 Dosificación terapéutica de una neurorregulina o una subsecuencia de la misma para el tratamiento o profilaxis de la falla cardiaca.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2011000696A MX2011000696A (es) 2008-07-17 2009-07-17 Dosificacion terapeutica de una neurregulina o una subsecuencia de la misma para el tratamiento o la profilaxis de insuficiencia cardiaca.

Country Status (13)

Country Link
US (5) US20110166068A1 (OSRAM)
EP (3) EP2320933B1 (OSRAM)
JP (5) JP5797112B2 (OSRAM)
CN (3) CN102159236A (OSRAM)
AU (3) AU2009292216B2 (OSRAM)
BR (1) BRPI0916442A2 (OSRAM)
CA (1) CA2731113A1 (OSRAM)
DK (2) DK3338791T3 (OSRAM)
ES (2) ES2664394T3 (OSRAM)
MX (2) MX2011000696A (OSRAM)
PL (2) PL2320933T3 (OSRAM)
RU (4) RU2536938C2 (OSRAM)
WO (1) WO2010030317A2 (OSRAM)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010030317A2 (en) 2008-07-17 2010-03-18 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure
EP3777878A1 (en) 2008-08-15 2021-02-17 Acorda Therapeutics, Inc. Compositions and methods for treatment during non-acute periods following cns neurological injury
JP5743898B2 (ja) 2008-11-28 2015-07-01 ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド ニューレグリンペプチド及びその使用
EP3235504B1 (en) 2009-10-14 2019-09-18 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun (Shanghai)Science & Technology Limited Compositions and methods for treating heart failure
EP3278811B1 (en) * 2012-03-30 2020-12-02 Acorda Therapeutics, Inc. Use of ggf2 to treat neuropathic pain upon peripheral nerve injury
US20160129084A1 (en) * 2013-03-06 2016-05-12 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure
CN105611955A (zh) 2013-05-22 2016-05-25 上海泽生科技开发有限公司 缓释纽兰格林治疗心力衰竭
CN104758922A (zh) 2014-01-03 2015-07-08 上海泽生科技开发有限公司 纽兰格林制剂的配方
CN105561298A (zh) * 2014-10-17 2016-05-11 上海泽生科技开发有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
CN108474787A (zh) 2015-09-25 2018-08-31 道格拉斯.B.索耶 用于治疗心脏损伤的方法
EP3445386B1 (en) * 2016-04-19 2020-08-26 Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI) Neuregulin for the treatment and/or prevention of tumors of the nervous system
CN110835368A (zh) * 2018-08-15 2020-02-25 上海泽生科技开发股份有限公司 神经调节蛋白多肽片段及其用途
AR121035A1 (es) 2019-04-01 2022-04-13 Lilly Co Eli Compuestos de neuregulina-4 y métodos de uso
AU2020348436A1 (en) * 2019-09-16 2022-04-07 Zensun (Shanghai) Science & Technology, Co., Ltd. Recombinant human neuregulin derivatives and use thereof
WO2023070078A1 (en) * 2021-10-22 2023-04-27 The Research Institute At Nationwide Children's Hospital Neuregulin for protection against respiratory viral infection and post-viral disease

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US7115554B1 (en) * 1993-05-06 2006-10-03 Acorda Therapeutics, Inc. Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III
US6087323A (en) 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
US5811098A (en) * 1992-11-24 1998-09-22 Bristol-Myers Squibb Company Antibodies to HER4, human receptor tyrosine kinase
US5912326A (en) 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
US6136558A (en) * 1997-02-10 2000-10-24 Genentech, Inc. Heregulin variants
US6051401A (en) 1998-07-28 2000-04-18 Bayer Corporation Methods and constructs for protein expression
SI1115417T1 (sl) 1998-09-25 2006-08-31 Cubist Pharm Inc Uporaba daptomicina
AUPP785098A0 (en) * 1998-12-21 1999-01-21 Victor Chang Cardiac Research Institute, The Treatment of heart disease
US6635249B1 (en) 1999-04-23 2003-10-21 Cenes Pharmaceuticals, Inc. Methods for treating congestive heart failure
CN1138785C (zh) * 1999-06-04 2004-02-18 周明东 生长因子神经调节蛋白及其类似物的新应用
WO2001034174A2 (en) 1999-11-12 2001-05-17 Entremed, Inc. Methods for administration of therapeutic agents on an antiangiogenic schedule
ES2370875T3 (es) 2000-05-23 2011-12-23 Acorda Therapeutics, Inc. Moléculas de ácido nucleico nrg-2, polipéptidos y métodos de diagnóstico y terapéuticos.
CU23157A1 (es) * 2001-01-03 2006-07-18 Ct Ingenieria Genetica Biotech COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL
EP1569689A4 (en) 2002-01-18 2009-08-05 Novartis Vaccines & Diagnostic IL2 / ANTI-HER2-ANTIBODY COMBINATION THERAPY AGAINST CANCER, which is characterized by overexpression of the HER2-RECEPTOR PROTEIN
WO2003099320A1 (en) * 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US20070032557A1 (en) * 2005-02-18 2007-02-08 Matti Kivikko Method for administering levosimendan
AR053690A1 (es) 2005-03-23 2007-05-16 Pfizer Prod Inc Terapia de cancer de prostata con anticuerpos contra ctla4 y terapia hormonal
US7776817B2 (en) 2005-09-02 2010-08-17 Morehouse School Of Medicine Neuregulins for prevention and treatment of damage from acute assault on vascular and neuronal tissue and as regulators of neuronal stem cell migration
US20070213264A1 (en) * 2005-12-02 2007-09-13 Mingdong Zhou Neuregulin variants and methods of screening and using thereof
EP2918283B1 (en) * 2005-12-30 2018-01-31 Zensun (Shanghai) Science & Technology, Co., Ltd. Extended release of neuregulin for improved cardiac function
US8410050B2 (en) 2008-02-29 2013-04-02 Acorda Therapeutics, Inc. Method for achieving desired glial growth factor 2 plasma levels
WO2010030317A2 (en) 2008-07-17 2010-03-18 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure
EP3235504B1 (en) 2009-10-14 2019-09-18 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2012021818A2 (en) 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use
EP3278811B1 (en) 2012-03-30 2020-12-02 Acorda Therapeutics, Inc. Use of ggf2 to treat neuropathic pain upon peripheral nerve injury

Also Published As

Publication number Publication date
US20130324466A1 (en) 2013-12-05
JP2022023208A (ja) 2022-02-07
US20110166068A1 (en) 2011-07-07
RU2719199C1 (ru) 2020-04-17
JP2011528353A (ja) 2011-11-17
JP2017200949A (ja) 2017-11-09
EP3338791A1 (en) 2018-06-27
PL2320933T3 (pl) 2018-07-31
US20160113999A1 (en) 2016-04-28
EP3338791B1 (en) 2019-09-18
EP3632459A1 (en) 2020-04-08
JP2019196370A (ja) 2019-11-14
CN102159236A (zh) 2011-08-17
CN104623633A (zh) 2015-05-20
HK1256637A1 (en) 2019-09-27
JP6189879B2 (ja) 2017-08-30
EP2320933A4 (en) 2013-02-27
CN107019794B (zh) 2021-03-12
US9198951B2 (en) 2015-12-01
JP2015129137A (ja) 2015-07-16
US20200009228A1 (en) 2020-01-09
AU2009292216B2 (en) 2015-03-05
EP2320933B1 (en) 2017-12-27
US9956266B2 (en) 2018-05-01
US11235031B2 (en) 2022-02-01
DK3338791T3 (da) 2019-12-16
AU2009292216A1 (en) 2010-03-18
AU2015202877B2 (en) 2017-03-09
CN107019794A (zh) 2017-08-08
AU2017203528A1 (en) 2017-06-15
RU2536938C2 (ru) 2014-12-27
RU2020111236A3 (OSRAM) 2021-09-21
ES2763184T3 (es) 2020-05-27
US20180280477A1 (en) 2018-10-04
ES2664394T3 (es) 2018-04-19
BRPI0916442A2 (pt) 2018-06-19
WO2010030317A2 (en) 2010-03-18
AU2015202877A1 (en) 2015-06-18
JP5797112B2 (ja) 2015-10-21
PL3338791T3 (pl) 2020-04-30
RU2020111236A (ru) 2021-09-21
MX2011000696A (es) 2011-07-29
CA2731113A1 (en) 2010-03-18
RU2014141514A (ru) 2016-05-10
DK2320933T3 (en) 2018-04-16
EP2320933A1 (en) 2011-05-18
RU2698090C2 (ru) 2019-08-22
RU2011105821A (ru) 2012-08-27

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