ES2664394T3 - Dosificación terapéutica de una neuregulina o de una subsecuencia de la misma para el tratamiento o la profilaxis de la insuficiencia cardiaca - Google Patents
Dosificación terapéutica de una neuregulina o de una subsecuencia de la misma para el tratamiento o la profilaxis de la insuficiencia cardiaca Download PDFInfo
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- ES2664394T3 ES2664394T3 ES09813336.6T ES09813336T ES2664394T3 ES 2664394 T3 ES2664394 T3 ES 2664394T3 ES 09813336 T ES09813336 T ES 09813336T ES 2664394 T3 ES2664394 T3 ES 2664394T3
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US13517108P | 2008-07-17 | 2008-07-17 | |
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| PCT/US2009/004130 WO2010030317A2 (en) | 2008-07-17 | 2009-07-17 | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
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| ES2664394T3 true ES2664394T3 (es) | 2018-04-19 |
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| ES17209369T Active ES2763184T3 (es) | 2008-07-17 | 2009-07-17 | Dosificación terapéutica de una neurregulina en el tratamiento o profilaxis de la insuficiencia cardíaca |
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| ES17209369T Active ES2763184T3 (es) | 2008-07-17 | 2009-07-17 | Dosificación terapéutica de una neurregulina en el tratamiento o profilaxis de la insuficiencia cardíaca |
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| EP (3) | EP2320933B1 (OSRAM) |
| JP (5) | JP5797112B2 (OSRAM) |
| CN (3) | CN107019794B (OSRAM) |
| AU (3) | AU2009292216B2 (OSRAM) |
| BR (1) | BRPI0916442A2 (OSRAM) |
| CA (1) | CA2731113A1 (OSRAM) |
| DK (2) | DK2320933T3 (OSRAM) |
| ES (2) | ES2664394T3 (OSRAM) |
| MX (2) | MX384378B (OSRAM) |
| PL (2) | PL2320933T3 (OSRAM) |
| RU (4) | RU2536938C2 (OSRAM) |
| WO (1) | WO2010030317A2 (OSRAM) |
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| AU2009292216B2 (en) | 2008-07-17 | 2015-03-05 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
| WO2010019275A2 (en) | 2008-08-15 | 2010-02-18 | Acorda Therapeutics, Inc. | Compositions and methods for treatment during non-acute periods following cns neurological injury |
| WO2010060265A1 (en) * | 2008-11-28 | 2010-06-03 | Zensun (Shanghai) Science & Technology Limited | Neuregulin peptides and their use |
| KR101933543B1 (ko) | 2009-10-14 | 2018-12-28 | 아코르다 쎄라퓨틱스 인코포레이티드 | 말초 신경 손상을 치료하기 위한 뉴레귤린의 용도 |
| WO2013053076A1 (en) * | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| CN104321072A (zh) * | 2012-03-30 | 2015-01-28 | 阿寇达医疗有限公司 | 神经调节蛋白在治疗外周神经损伤中的应用 |
| EP2964249A1 (en) * | 2013-03-06 | 2016-01-13 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure |
| BR112015029293A2 (pt) | 2013-05-22 | 2018-04-24 | Zensun Shanghai Science & Tech Ltd | método e kit para prevenir, tratar ou retardar uma doença ou distúrbio cardiovascular em um mamífero |
| CN110946993A (zh) | 2014-01-03 | 2020-04-03 | 上海泽生科技开发股份有限公司 | 纽兰格林制剂的配方 |
| CN105561298A (zh) | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| CA2999301A1 (en) | 2015-09-25 | 2017-03-30 | Douglas B. Sawyer | Methods for treating cardiac injury |
| EP3445386B1 (en) * | 2016-04-19 | 2020-08-26 | Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI) | Neuregulin for the treatment and/or prevention of tumors of the nervous system |
| CN110835368A (zh) * | 2018-08-15 | 2020-02-25 | 上海泽生科技开发股份有限公司 | 神经调节蛋白多肽片段及其用途 |
| AR121035A1 (es) | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
| US20230057622A1 (en) * | 2019-09-16 | 2023-02-23 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Recombinant Human Neuregulin Derivatives and Use Thereof |
| WO2023070078A1 (en) * | 2021-10-22 | 2023-04-27 | The Research Institute At Nationwide Children's Hospital | Neuregulin for protection against respiratory viral infection and post-viral disease |
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| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US7115554B1 (en) * | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
| US7037888B1 (en) | 1992-04-03 | 2006-05-02 | Acorda Therapeutics, Inc. | Methods for treating muscle diseases and disorders |
| US6087323A (en) | 1992-04-03 | 2000-07-11 | Cambridge Neuroscience, Inc. | Use of neuregulins as modulators of cellular communication |
| US5811098A (en) * | 1992-11-24 | 1998-09-22 | Bristol-Myers Squibb Company | Antibodies to HER4, human receptor tyrosine kinase |
| US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
| US6136558A (en) * | 1997-02-10 | 2000-10-24 | Genentech, Inc. | Heregulin variants |
| US6051401A (en) | 1998-07-28 | 2000-04-18 | Bayer Corporation | Methods and constructs for protein expression |
| EP1674107B8 (en) | 1998-09-25 | 2017-01-25 | Cubist Pharmaceuticals LLC | Use of daptomycin |
| AUPP785098A0 (en) * | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
| US6635249B1 (en) * | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| CN1138785C (zh) * | 1999-06-04 | 2004-02-18 | 周明东 | 生长因子神经调节蛋白及其类似物的新应用 |
| AU1916301A (en) | 1999-11-12 | 2001-06-06 | Children's Medical Center Corporation | Methods for administration of therapeutic agents on an antiangiogenic schedule |
| CA2409996C (en) | 2000-05-23 | 2016-03-01 | Cenes Pharmaceuticals, Inc. | Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| AU2003210549A1 (en) | 2002-01-18 | 2003-09-02 | Chiron Corporation | Combination il-2/anti-herz antibody therapy for cancers characterized by overexpression of the her2 receptor protein |
| WO2003099320A1 (en) * | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| US20070032557A1 (en) * | 2005-02-18 | 2007-02-08 | Matti Kivikko | Method for administering levosimendan |
| WO2006101691A1 (en) | 2005-03-23 | 2006-09-28 | Pfizer Products Inc. | Therapy of prostate cancer with ctla4 antibodies and hormonal therapy |
| US7776817B2 (en) | 2005-09-02 | 2010-08-17 | Morehouse School Of Medicine | Neuregulins for prevention and treatment of damage from acute assault on vascular and neuronal tissue and as regulators of neuronal stem cell migration |
| US20070213264A1 (en) * | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
| EP3363455A1 (en) | 2005-12-30 | 2018-08-22 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Extended release of neuregulin for improved cardiac function |
| RU2530650C2 (ru) | 2008-02-29 | 2014-10-10 | Акорда Терапьютикс, Инк. | Способ обеспечения требуемых уровней фактора 2 роста глии в плазме |
| AU2009292216B2 (en) | 2008-07-17 | 2015-03-05 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
| KR101933543B1 (ko) | 2009-10-14 | 2018-12-28 | 아코르다 쎄라퓨틱스 인코포레이티드 | 말초 신경 손상을 치료하기 위한 뉴레귤린의 용도 |
| CA2845198A1 (en) | 2010-08-13 | 2012-02-16 | Georgetown University | Ggf2 and methods of use |
| CN104321072A (zh) | 2012-03-30 | 2015-01-28 | 阿寇达医疗有限公司 | 神经调节蛋白在治疗外周神经损伤中的应用 |
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2009
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2013
- 2013-05-29 US US13/904,654 patent/US9198951B2/en active Active
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2014
- 2014-10-14 RU RU2014141514A patent/RU2698090C2/ru active
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2015
- 2015-01-27 JP JP2015013248A patent/JP6189879B2/ja not_active Expired - Fee Related
- 2015-05-27 AU AU2015202877A patent/AU2015202877B2/en not_active Ceased
- 2015-10-30 US US14/928,124 patent/US9956266B2/en active Active
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2017
- 2017-05-26 AU AU2017203528A patent/AU2017203528A1/en not_active Abandoned
- 2017-08-03 JP JP2017150365A patent/JP2017200949A/ja active Pending
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2018
- 2018-03-29 US US15/940,250 patent/US20180280477A1/en not_active Abandoned
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2019
- 2019-07-03 JP JP2019124501A patent/JP2019196370A/ja active Pending
- 2019-08-12 RU RU2019125376A patent/RU2719199C1/ru active
- 2019-09-09 US US16/564,739 patent/US11235031B2/en active Active
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2020
- 2020-03-18 RU RU2020111236A patent/RU2020111236A/ru unknown
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2021
- 2021-11-04 JP JP2021179961A patent/JP2022023208A/ja active Pending
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