MX378970B - Proteína sin fenilalanina para el tratamiento de pku. - Google Patents

Proteína sin fenilalanina para el tratamiento de pku.

Info

Publication number
MX378970B
MX378970B MX2019002422A MX2019002422A MX378970B MX 378970 B MX378970 B MX 378970B MX 2019002422 A MX2019002422 A MX 2019002422A MX 2019002422 A MX2019002422 A MX 2019002422A MX 378970 B MX378970 B MX 378970B
Authority
MX
Mexico
Prior art keywords
protein
phenylalanine
pku
treatment
dietary
Prior art date
Application number
MX2019002422A
Other languages
English (en)
Other versions
MX2019002422A (es
Inventor
Bernhard Hoffmann
Natalia Jablonka
Stefan Rasche
Stefan Schillberg
Yvonne Mücke
Original Assignee
Metax Inst Fuer Diaetetik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metax Inst Fuer Diaetetik Gmbh filed Critical Metax Inst Fuer Diaetetik Gmbh
Publication of MX2019002422A publication Critical patent/MX2019002422A/es
Publication of MX378970B publication Critical patent/MX378970B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/195—Proteins from microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/54—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Soy Sauces And Products Related Thereto (AREA)

Abstract

Se proporciona una proteína dietética recombinante que está libre de fenilalanina y es una proteína dietética con un alto valor biológico. Se proporcionan además un vector que codifica para la proteína dietética, microorganismos que expresan la proteína, un método para la producción de la proteína y una composición dietética que comprende la proteína que en una modalidad es para usarse como un medicamento y/o alimento para propósitos médicos especiales en pacientes con acumulaciones de fenilalanina en el cuerpo.
MX2019002422A 2016-09-01 2017-08-30 Proteína sin fenilalanina para el tratamiento de pku. MX378970B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16186895.5A EP3290436B1 (en) 2016-09-01 2016-09-01 Phenylalanine-free protein for the treatment of pku
PCT/EP2017/071814 WO2018041920A1 (en) 2016-09-01 2017-08-30 Phenylalanine-free protein for the treatment of pku

Publications (2)

Publication Number Publication Date
MX2019002422A MX2019002422A (es) 2019-07-04
MX378970B true MX378970B (es) 2025-03-10

Family

ID=56883591

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019002422A MX378970B (es) 2016-09-01 2017-08-30 Proteína sin fenilalanina para el tratamiento de pku.

Country Status (28)

Country Link
US (1) US10640538B2 (es)
EP (1) EP3290436B1 (es)
JP (1) JP6954676B2 (es)
CN (1) CN109661401B (es)
AU (1) AU2017317652B2 (es)
BR (1) BR112019004270A2 (es)
CA (1) CA3033271C (es)
CY (1) CY1121886T1 (es)
DK (1) DK3290436T3 (es)
ES (1) ES2742175T3 (es)
HR (1) HRP20191406T1 (es)
HU (1) HUE044665T2 (es)
IL (1) IL265015B2 (es)
LT (1) LT3290436T (es)
MA (1) MA43352B1 (es)
MD (1) MD3290436T2 (es)
ME (1) ME03510B (es)
MX (1) MX378970B (es)
NZ (1) NZ750498A (es)
PL (1) PL3290436T3 (es)
PT (1) PT3290436T (es)
RU (1) RU2764796C2 (es)
SA (1) SA519401175B1 (es)
SI (1) SI3290436T1 (es)
SM (1) SMT201900464T1 (es)
UA (1) UA124630C2 (es)
WO (1) WO2018041920A1 (es)
ZA (1) ZA201901505B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110747218A (zh) * 2019-09-27 2020-02-04 深圳市诺维健生物技术有限责任公司 一种特殊膳食蛋白质的生产方法与应用
CN110746494B (zh) * 2019-09-27 2021-07-20 深圳市诺维健生物技术有限责任公司 一组特殊膳食蛋白质

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04126051A (ja) * 1990-09-18 1992-04-27 Snow Brand Milk Prod Co Ltd フェニルケトン尿症患者用栄養調製物
GB9310472D0 (en) 1993-05-20 1993-07-07 Univ Warwick Phenylalanine-free protein and dna coding thereof
GB9314802D0 (en) * 1993-07-16 1993-08-25 Pharmaceutical Proteins Ltd Modified proteins
AU4413096A (en) 1994-12-02 1996-06-19 Indiana University Foundation Phenylalanine free proteins
EP1092769B1 (de) * 1999-10-15 2008-10-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Polypeptid-Tag's für den Nachweis und die Aufreinigung von Polypeptiden
CN1300328C (zh) * 2000-12-07 2007-02-14 Dsmip资产有限公司 富含具有羧基末端脯氨酸残基的肽的蛋白质水解产物
US9034402B2 (en) * 2007-04-16 2015-05-19 Solae, Llc Protein hydrolysate compositions having improved sensory characteristics and physical properties
CA2685326A1 (en) 2007-04-27 2008-11-06 Dow Global Technologies Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
WO2010124180A1 (en) * 2009-04-23 2010-10-28 Phasebio Pharmaceuticals, Inc. Phenylalanine hydroxylase fusion protein and methods for treating phenylketonuria
WO2013133691A1 (en) * 2012-03-09 2013-09-12 N.V. Nutricia Liquid nutritional composition comprising free amino acids
US20150126441A1 (en) 2012-03-26 2015-05-07 Pronutria, Inc. Nutritive Fragments and Proteins with Low or No Phenylalanine and Methods
JP2016500250A (ja) 2012-11-20 2016-01-12 プロニュートリア・インコーポレイテッドＰｒｏｎｕｔｒｉａ， Ｉｎｃ． 改変された分泌タンパク質及び方法
DK3197472T3 (da) 2014-09-22 2021-10-18 Tanea Medical Ab Rekombinante phe-frie proteiner til anvendelse i behandlingen af phenylketonuri

Also Published As

Publication number Publication date
ES2742175T3 (es) 2020-02-13
LT3290436T (lt) 2019-10-10
MX2019002422A (es) 2019-07-04
RU2019109142A3 (es) 2021-01-27
CA3033271C (en) 2024-04-02
CY1121886T1 (el) 2020-10-14
ME03510B (me) 2020-04-20
EP3290436A1 (en) 2018-03-07
NZ750498A (en) 2023-01-27
ZA201901505B (en) 2020-08-26
HUE044665T2 (hu) 2019-11-28
CN109661401B (zh) 2023-12-19
CN109661401A (zh) 2019-04-19
SA519401175B1 (ar) 2022-01-08
EP3290436B1 (en) 2019-06-05
AU2017317652A1 (en) 2019-02-28
MD3290436T2 (ro) 2019-10-31
CA3033271A1 (en) 2018-03-08
IL265015B1 (en) 2024-04-01
BR112019004270A2 (pt) 2019-06-04
PT3290436T (pt) 2019-08-30
JP6954676B2 (ja) 2021-10-27
IL265015B2 (en) 2024-08-01
UA124630C2 (uk) 2021-10-20
SI3290436T1 (sl) 2019-11-29
AU2017317652B2 (en) 2020-11-19
MA43352B1 (fr) 2019-08-30
RU2019109142A (ru) 2020-10-01
IL265015A (es) 2019-04-30
SMT201900464T1 (it) 2020-01-14
JP2019533988A (ja) 2019-11-28
WO2018041920A1 (en) 2018-03-08
US20190202872A1 (en) 2019-07-04
MA43352A (fr) 2018-03-07
HRP20191406T1 (hr) 2019-11-15
RU2764796C2 (ru) 2022-01-21
DK3290436T3 (da) 2019-08-19
US10640538B2 (en) 2020-05-05
PL3290436T3 (pl) 2020-01-31

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