MX378944B - Anticuerpos de antígeno anti-tf humanizado. - Google Patents
Anticuerpos de antígeno anti-tf humanizado.Info
- Publication number
- MX378944B MX378944B MX2016013686A MX2016013686A MX378944B MX 378944 B MX378944 B MX 378944B MX 2016013686 A MX2016013686 A MX 2016013686A MX 2016013686 A MX2016013686 A MX 2016013686A MX 378944 B MX378944 B MX 378944B
- Authority
- MX
- Mexico
- Prior art keywords
- mabs
- fragments
- methods
- humanized anti
- distinct
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000002059 diagnostic imaging Methods 0.000 abstract 1
- 238000012606 in vitro cell culture Methods 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461981240P | 2014-04-18 | 2014-04-18 | |
| PCT/US2015/026595 WO2015161311A2 (en) | 2014-04-18 | 2015-04-20 | Humanized anti-tf-antigen antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016013686A MX2016013686A (es) | 2017-03-31 |
| MX378944B true MX378944B (es) | 2025-03-10 |
Family
ID=54324717
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016013686A MX378944B (es) | 2014-04-18 | 2015-04-20 | Anticuerpos de antígeno anti-tf humanizado. |
| MX2021000439A MX2021000439A (es) | 2014-04-18 | 2016-10-18 | Anticuerpos de antigeno anti-tf humanizado. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021000439A MX2021000439A (es) | 2014-04-18 | 2016-10-18 | Anticuerpos de antigeno anti-tf humanizado. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11130821B2 (Direct) |
| EP (2) | EP3797793A1 (Direct) |
| JP (1) | JP6740135B2 (Direct) |
| KR (1) | KR102413809B1 (Direct) |
| CN (1) | CN106488774B (Direct) |
| AU (1) | AU2015247358B2 (Direct) |
| BR (1) | BR112016024214B8 (Direct) |
| ES (1) | ES2843546T3 (Direct) |
| MX (2) | MX378944B (Direct) |
| RU (1) | RU2699717C2 (Direct) |
| WO (1) | WO2015161311A2 (Direct) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3609922A2 (en) * | 2017-04-13 | 2020-02-19 | Aduro Biotech Holdings, Europe B.V. | Anti-sirp alpha antibodies |
| WO2019060718A1 (en) * | 2017-09-22 | 2019-03-28 | Immunogen, Inc. | SEPARATION OF LIGHT TRIPLE CHAIN ANTIBODIES USING CATION EXCHANGE CHROMATOGRAPHY |
| US12060427B2 (en) * | 2018-03-28 | 2024-08-13 | Mitsubishi Tanabe Pharma Corporat | Drug conjugates of cMET monoclonal binding agents, and uses thereof |
| EP3801618A4 (en) * | 2018-05-30 | 2022-07-27 | National Health Research Institutes | Anti-abeta antibodies and uses thereof |
| BR112021012040A2 (pt) | 2018-12-21 | 2021-11-03 | Ose Immunotherapeutics | Molécula anti-pd-1/sirpa bifuncional |
| CA3123338A1 (en) | 2018-12-21 | 2020-06-25 | Ose Immunotherapeutics | Bifunctional anti-pd-1/il-7 molecule |
| BR112021012027A2 (pt) | 2018-12-21 | 2021-11-03 | Ose Immunotherapeutics | Molécula bifuncional direcionada contra pd-1 humano |
| JP7043685B2 (ja) | 2018-12-21 | 2022-03-29 | オーエスイー・イミュノセラピューティクス | ヒト化抗ヒトｐｄ－１抗体 |
| WO2020165374A1 (en) | 2019-02-14 | 2020-08-20 | Ose Immunotherapeutics | Bifunctional molecule comprising il-15ra |
| TW202202521A (zh) * | 2020-03-23 | 2022-01-16 | 美商必治妥美雅史谷比公司 | 用於治療癌症之抗ccr8抗體 |
| CN121270708A (zh) * | 2025-12-08 | 2026-01-06 | 宁波大学附属第一医院 | 一种纳米抗体及其在制备cd176阳性肿瘤癌症治疗或诊断药物中的应用 |
| CN121270707A (zh) * | 2025-12-08 | 2026-01-06 | 宁波大学附属第一医院 | 一种特异性结合cd176蛋白的纳米抗体及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050260680A1 (en) * | 2004-04-16 | 2005-11-24 | Vanderbilt University | Methods of diagnosing and treating autoimmune diseases |
| US7374755B2 (en) * | 2004-07-26 | 2008-05-20 | The Research Foundation Of State University Of New York | Therapeutic use of anti-TF-Antigen antibody |
| GB0510790D0 (en) * | 2005-05-26 | 2005-06-29 | Syngenta Crop Protection Ag | Anti-CD16 binding molecules |
| KR20080113236A (ko) | 2006-03-21 | 2008-12-29 | 와이어쓰 | Ｒａｇｅ를 길항하기 위한 방법 및 조성물 |
| EP2161031A1 (en) * | 2008-09-05 | 2010-03-10 | SuppreMol GmbH | Fc gamma receptor for the treatment of B cell mediated multiple sclerosis |
| MX351635B (es) * | 2009-10-16 | 2017-10-23 | Servier Lab | Anticuerpos monoclonales frente a progastrina y sus usos. |
| EP2347769A1 (en) * | 2010-01-20 | 2011-07-27 | Glycotope GmbH | Cancer stem cell markers and uses thereof |
| EP2407487A1 (en) | 2010-07-14 | 2012-01-18 | F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. | Multispecific modular antibody |
| WO2012143524A2 (en) | 2011-04-20 | 2012-10-26 | Genmab A/S | Bispecific antibodies against her2 and cd3 |
| JP6124800B2 (ja) * | 2011-11-30 | 2017-05-10 | 中外製薬株式会社 | 免疫複合体を形成する細胞内への運搬体（キャリア）を含む医薬 |
| CN102796144A (zh) * | 2012-08-22 | 2012-11-28 | 山东大学 | Tf抗原及其类似物、和其化学酶法合成方法及其应用 |
| US10023651B2 (en) * | 2014-04-18 | 2018-07-17 | The Research Foundation For The State University Of New York | Humanized anti-TF-antigen antibodies |
-
2015
- 2015-04-20 RU RU2016143552A patent/RU2699717C2/ru active
- 2015-04-20 MX MX2016013686A patent/MX378944B/es unknown
- 2015-04-20 KR KR1020167031646A patent/KR102413809B1/ko active Active
- 2015-04-20 EP EP20197413.6A patent/EP3797793A1/en active Pending
- 2015-04-20 EP EP15780559.9A patent/EP3131581B1/en active Active
- 2015-04-20 JP JP2016558558A patent/JP6740135B2/ja active Active
- 2015-04-20 CN CN201580027114.8A patent/CN106488774B/zh active Active
- 2015-04-20 BR BR112016024214A patent/BR112016024214B8/pt active IP Right Grant
- 2015-04-20 AU AU2015247358A patent/AU2015247358B2/en active Active
- 2015-04-20 ES ES15780559T patent/ES2843546T3/es active Active
- 2015-04-20 WO PCT/US2015/026595 patent/WO2015161311A2/en not_active Ceased
-
2016
- 2016-10-18 MX MX2021000439A patent/MX2021000439A/es unknown
-
2018
- 2018-05-10 US US15/976,500 patent/US11130821B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2843546T3 (es) | 2021-07-19 |
| EP3797793A1 (en) | 2021-03-31 |
| CA2943681A1 (en) | 2015-10-22 |
| WO2015161311A3 (en) | 2015-12-10 |
| EP3131581A2 (en) | 2017-02-22 |
| JP6740135B2 (ja) | 2020-08-12 |
| MX2016013686A (es) | 2017-03-31 |
| EP3131581A4 (en) | 2018-02-21 |
| CN106488774A (zh) | 2017-03-08 |
| RU2699717C2 (ru) | 2019-09-09 |
| CN106488774B (zh) | 2019-11-01 |
| RU2016143552A3 (Direct) | 2018-11-14 |
| BR112016024214B8 (pt) | 2023-12-26 |
| KR20170010356A (ko) | 2017-01-31 |
| MX2021000439A (es) | 2021-03-25 |
| US20180258182A1 (en) | 2018-09-13 |
| KR102413809B1 (ko) | 2022-06-28 |
| EP3131581B1 (en) | 2020-09-23 |
| BR112016024214B1 (pt) | 2023-11-14 |
| JP2017518260A (ja) | 2017-07-06 |
| US11130821B2 (en) | 2021-09-28 |
| AU2015247358B2 (en) | 2020-02-27 |
| WO2015161311A2 (en) | 2015-10-22 |
| BR112016024214A2 (pt) | 2018-01-23 |
| AU2015247358A1 (en) | 2016-11-10 |
| RU2016143552A (ru) | 2018-05-21 |
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