MX367903B - Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma. - Google Patents

Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma.

Info

Publication number
MX367903B
MX367903B MX2014005006A MX2014005006A MX367903B MX 367903 B MX367903 B MX 367903B MX 2014005006 A MX2014005006 A MX 2014005006A MX 2014005006 A MX2014005006 A MX 2014005006A MX 367903 B MX367903 B MX 367903B
Authority
MX
Mexico
Prior art keywords
fibrin sealant
preparing
sealant component
highly concentrated
concentrated fibrinogen
Prior art date
Application number
MX2014005006A
Other languages
English (en)
Other versions
MX2014005006A (es
Inventor
Sic Jim Jun
Sul Lee Gun
Kim Ki-Yong
Kang Yong
Hwan Son Ki
Original Assignee
Green Cross Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Holdings Corp filed Critical Green Cross Holdings Corp
Publication of MX2014005006A publication Critical patent/MX2014005006A/es
Publication of MX367903B publication Critical patent/MX367903B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La presente invención se refiere a un método para preparar un componente sellador de fibrina 1, caracterizado porque comprende: agregar aminoácidos o derivados de aminoácidos, y sales a una solución de fibrinógeno precariamente concentrada; realizar ultra filtración para obtener una solución de fibrinógeno altamente concentrada; agregar al menos un material seleccionado de un grupo que consiste de aprotinina, detergente, y albúmina; y agregar el Factor XIII antes o después de realizar la ultra filtración.
MX2014005006A 2011-10-27 2012-10-24 Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma. MX367903B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110110526A KR101127127B1 (ko) 2011-10-27 2011-10-27 고농도 피브리노겐 용액의 제조 방법 및 이를 이용한 피브린 실란트 제품의 제조방법
PCT/KR2012/008755 WO2013062305A1 (en) 2011-10-27 2012-10-24 Method for preparing highly concentrated fibrinogen solution and method for preparing fibrin sealant by using thereof

Publications (2)

Publication Number Publication Date
MX2014005006A MX2014005006A (es) 2014-11-25
MX367903B true MX367903B (es) 2019-09-10

Family

ID=46142315

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014005006A MX367903B (es) 2011-10-27 2012-10-24 Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma.

Country Status (7)

Country Link
US (1) US10493133B2 (es)
KR (1) KR101127127B1 (es)
CN (2) CN104105502A (es)
BR (1) BR112014009923B1 (es)
CA (1) CA2852019C (es)
MX (1) MX367903B (es)
WO (1) WO2013062305A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014196674A1 (ko) * 2013-06-07 2014-12-11 주식회사 청진바이오텍 알러지성분이 분리된 분리정제봉독 제조방법
JP2019524704A (ja) * 2016-07-06 2019-09-05 ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 安定な液体フィブリノーゲン
FR3061020B1 (fr) * 2016-12-22 2019-05-17 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Composition de fibrinogene humain
CN116744986A (zh) 2020-12-25 2023-09-12 广州倍绣生物技术有限公司 纤维蛋白原除菌过滤
AU2022426762A1 (en) * 2021-12-30 2024-07-04 Baxter Healthcare Sa Fibrinogen and thrombin solutions for a fibrin sealant and fibrin sealant kit
CN115110176A (zh) * 2022-08-10 2022-09-27 江苏康溢臣生命科技有限公司 一种雪莲蛋白纤维的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19617369A1 (de) * 1996-04-30 1997-11-06 Immuno Ag Lagerstabile Fibrinogen-Präparate
US7276235B2 (en) * 1998-11-18 2007-10-02 Zlb Behring Gmbh Tissue glue with improved antiadhesive properties
WO2000047621A1 (en) * 1999-02-12 2000-08-17 Baxter Aktiengesellschaft A method for producing a preparation based on fibrinogen and fibronectin as well as protein compositions obtainable according to this method
ES2206298T3 (es) * 1999-08-13 2004-05-16 Omrix Biopharmaceuticals S.A. Uso de multimeros de fibrinogeno en agentes obturadores de fibrina.
CN1606447A (zh) * 2001-10-03 2005-04-13 克里斯托弗·J·伍尔弗顿 保存稳定的纤维蛋白原溶液
CN1599616A (zh) * 2001-10-03 2005-03-23 克里斯托弗·J·伍尔弗顿 贮存稳定的人纤维蛋白原溶液
CA2473727A1 (en) * 2001-12-04 2003-06-12 Christopher J. Woolverton Storage-stable fibrin sealant
DE10261126A1 (de) 2002-08-13 2004-03-04 Aventis Behring Gmbh Lagerungsstabile, flüssige Fibrinogen-Formulierung
JPWO2004018615A1 (ja) * 2002-08-23 2005-12-08 旭化成メディカル株式会社 フィブリン含有組成物
WO2008117746A1 (ja) * 2007-03-22 2008-10-02 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 固体状フィブリノゲン製剤
CN101214391B (zh) * 2007-12-27 2010-05-19 广州倍绣生物技术有限公司 一种高效生物胶封闭剂及其应用
RS61082B1 (sr) * 2010-02-26 2020-12-31 Novo Nordisk As Stabilno antitelo koje sadrži kompozicije

Also Published As

Publication number Publication date
BR112014009923A8 (pt) 2018-02-06
BR112014009923B1 (pt) 2022-04-12
US10493133B2 (en) 2019-12-03
CN106178092A (zh) 2016-12-07
CA2852019C (en) 2017-05-23
BR112014009923A2 (pt) 2017-04-25
CA2852019A1 (en) 2013-05-02
CN104105502A (zh) 2014-10-15
US20140328822A1 (en) 2014-11-06
WO2013062305A1 (en) 2013-05-02
KR101127127B1 (ko) 2012-03-21
MX2014005006A (es) 2014-11-25
CN106178092B (zh) 2019-06-25

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Owner name: GREEN CROSS HOLDINGS CORPORATION

FG Grant or registration