MX367903B - Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma. - Google Patents
Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma.Info
- Publication number
- MX367903B MX367903B MX2014005006A MX2014005006A MX367903B MX 367903 B MX367903 B MX 367903B MX 2014005006 A MX2014005006 A MX 2014005006A MX 2014005006 A MX2014005006 A MX 2014005006A MX 367903 B MX367903 B MX 367903B
- Authority
- MX
- Mexico
- Prior art keywords
- fibrin sealant
- preparing
- sealant component
- highly concentrated
- concentrated fibrinogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Abstract
La presente invención se refiere a un método para preparar un componente sellador de fibrina 1, caracterizado porque comprende: agregar aminoácidos o derivados de aminoácidos, y sales a una solución de fibrinógeno precariamente concentrada; realizar ultra filtración para obtener una solución de fibrinógeno altamente concentrada; agregar al menos un material seleccionado de un grupo que consiste de aprotinina, detergente, y albúmina; y agregar el Factor XIII antes o después de realizar la ultra filtración.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020110110526A KR101127127B1 (ko) | 2011-10-27 | 2011-10-27 | 고농도 피브리노겐 용액의 제조 방법 및 이를 이용한 피브린 실란트 제품의 제조방법 |
PCT/KR2012/008755 WO2013062305A1 (en) | 2011-10-27 | 2012-10-24 | Method for preparing highly concentrated fibrinogen solution and method for preparing fibrin sealant by using thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014005006A MX2014005006A (es) | 2014-11-25 |
MX367903B true MX367903B (es) | 2019-09-10 |
Family
ID=46142315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014005006A MX367903B (es) | 2011-10-27 | 2012-10-24 | Metodo para preparar solucion de fibrinogeno altamente concentrada y metodo para preparar sellador de fibrina al usar la misma. |
Country Status (7)
Country | Link |
---|---|
US (1) | US10493133B2 (es) |
KR (1) | KR101127127B1 (es) |
CN (2) | CN104105502A (es) |
BR (1) | BR112014009923B1 (es) |
CA (1) | CA2852019C (es) |
MX (1) | MX367903B (es) |
WO (1) | WO2013062305A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014196674A1 (ko) * | 2013-06-07 | 2014-12-11 | 주식회사 청진바이오텍 | 알러지성분이 분리된 분리정제봉독 제조방법 |
JP2019524704A (ja) * | 2016-07-06 | 2019-09-05 | ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーLaboratoire Francais Du Fractionnement Et Des Biotechnologies | 安定な液体フィブリノーゲン |
FR3061020B1 (fr) * | 2016-12-22 | 2019-05-17 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Composition de fibrinogene humain |
CN116744986A (zh) | 2020-12-25 | 2023-09-12 | 广州倍绣生物技术有限公司 | 纤维蛋白原除菌过滤 |
AU2022426762A1 (en) * | 2021-12-30 | 2024-07-04 | Baxter Healthcare Sa | Fibrinogen and thrombin solutions for a fibrin sealant and fibrin sealant kit |
CN115110176A (zh) * | 2022-08-10 | 2022-09-27 | 江苏康溢臣生命科技有限公司 | 一种雪莲蛋白纤维的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19617369A1 (de) * | 1996-04-30 | 1997-11-06 | Immuno Ag | Lagerstabile Fibrinogen-Präparate |
US7276235B2 (en) * | 1998-11-18 | 2007-10-02 | Zlb Behring Gmbh | Tissue glue with improved antiadhesive properties |
WO2000047621A1 (en) * | 1999-02-12 | 2000-08-17 | Baxter Aktiengesellschaft | A method for producing a preparation based on fibrinogen and fibronectin as well as protein compositions obtainable according to this method |
ES2206298T3 (es) * | 1999-08-13 | 2004-05-16 | Omrix Biopharmaceuticals S.A. | Uso de multimeros de fibrinogeno en agentes obturadores de fibrina. |
CN1606447A (zh) * | 2001-10-03 | 2005-04-13 | 克里斯托弗·J·伍尔弗顿 | 保存稳定的纤维蛋白原溶液 |
CN1599616A (zh) * | 2001-10-03 | 2005-03-23 | 克里斯托弗·J·伍尔弗顿 | 贮存稳定的人纤维蛋白原溶液 |
CA2473727A1 (en) * | 2001-12-04 | 2003-06-12 | Christopher J. Woolverton | Storage-stable fibrin sealant |
DE10261126A1 (de) | 2002-08-13 | 2004-03-04 | Aventis Behring Gmbh | Lagerungsstabile, flüssige Fibrinogen-Formulierung |
JPWO2004018615A1 (ja) * | 2002-08-23 | 2005-12-08 | 旭化成メディカル株式会社 | フィブリン含有組成物 |
WO2008117746A1 (ja) * | 2007-03-22 | 2008-10-02 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | 固体状フィブリノゲン製剤 |
CN101214391B (zh) * | 2007-12-27 | 2010-05-19 | 广州倍绣生物技术有限公司 | 一种高效生物胶封闭剂及其应用 |
RS61082B1 (sr) * | 2010-02-26 | 2020-12-31 | Novo Nordisk As | Stabilno antitelo koje sadrži kompozicije |
-
2011
- 2011-10-27 KR KR1020110110526A patent/KR101127127B1/ko active IP Right Grant
-
2012
- 2012-10-24 WO PCT/KR2012/008755 patent/WO2013062305A1/en active Application Filing
- 2012-10-24 CA CA2852019A patent/CA2852019C/en active Active
- 2012-10-24 US US14/351,902 patent/US10493133B2/en active Active
- 2012-10-24 CN CN201280052843.5A patent/CN104105502A/zh active Pending
- 2012-10-24 MX MX2014005006A patent/MX367903B/es active IP Right Grant
- 2012-10-24 CN CN201610538565.4A patent/CN106178092B/zh active Active
- 2012-10-24 BR BR112014009923-5A patent/BR112014009923B1/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
BR112014009923A8 (pt) | 2018-02-06 |
BR112014009923B1 (pt) | 2022-04-12 |
US10493133B2 (en) | 2019-12-03 |
CN106178092A (zh) | 2016-12-07 |
CA2852019C (en) | 2017-05-23 |
BR112014009923A2 (pt) | 2017-04-25 |
CA2852019A1 (en) | 2013-05-02 |
CN104105502A (zh) | 2014-10-15 |
US20140328822A1 (en) | 2014-11-06 |
WO2013062305A1 (en) | 2013-05-02 |
KR101127127B1 (ko) | 2012-03-21 |
MX2014005006A (es) | 2014-11-25 |
CN106178092B (zh) | 2019-06-25 |
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Legal Events
Date | Code | Title | Description |
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GB | Transfer or rights |
Owner name: GREEN CROSS HOLDINGS CORPORATION |
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FG | Grant or registration |