MX366887B - Tetrahidrato de la sal de l-arginina del ácido s-(-)-9-fluoro-6,7-dihidro-8- (4-hidroxipiperidin-1-il) -5-metil-1-oxo-1h, 5h-benzo[i,j] quinolizin-2-carboxílico puro, y un proceso para su preparación. - Google Patents
Tetrahidrato de la sal de l-arginina del ácido s-(-)-9-fluoro-6,7-dihidro-8- (4-hidroxipiperidin-1-il) -5-metil-1-oxo-1h, 5h-benzo[i,j] quinolizin-2-carboxílico puro, y un proceso para su preparación.Info
- Publication number
- MX366887B MX366887B MX2014003770A MX2014003770A MX366887B MX 366887 B MX366887 B MX 366887B MX 2014003770 A MX2014003770 A MX 2014003770A MX 2014003770 A MX2014003770 A MX 2014003770A MX 366887 B MX366887 B MX 366887B
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxypiperidin
- quinolizine
- benzo
- dihydro
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Se describe tetrahidrato de la sal de L-arginina del ácido S-(-)-9-fluoro-6,7-dihidro-8-(4-hidroxipiperidin-1-il) 5-metil-1-oxo-1H,5H-benzo[i,j] quinolizin-2-carboxílico puro y un proceso para su preparación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2740MU2011 | 2011-09-28 | ||
PCT/IB2012/050074 WO2013046061A1 (en) | 2011-09-28 | 2012-01-06 | Pures-(-)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1h,-5h-benzo[i,j]quinolizine-2- carboxylic acid l-arginine salt tetrahydrate and a process for its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014003770A MX2014003770A (es) | 2014-04-30 |
MX366887B true MX366887B (es) | 2019-07-29 |
Family
ID=45498072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014003770A MX366887B (es) | 2011-09-28 | 2012-01-06 | Tetrahidrato de la sal de l-arginina del ácido s-(-)-9-fluoro-6,7-dihidro-8- (4-hidroxipiperidin-1-il) -5-metil-1-oxo-1h, 5h-benzo[i,j] quinolizin-2-carboxílico puro, y un proceso para su preparación. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20140296280A1 (es) |
EP (1) | EP2776433A1 (es) |
JP (1) | JP6126102B2 (es) |
KR (1) | KR20140054307A (es) |
CN (1) | CN103842361A (es) |
AU (1) | AU2012313987B2 (es) |
BR (1) | BR112014006401A2 (es) |
CA (1) | CA2850159A1 (es) |
MX (1) | MX366887B (es) |
RU (1) | RU2594166C2 (es) |
WO (1) | WO2013046061A1 (es) |
ZA (1) | ZA201401262B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019522052A (ja) * | 2017-04-14 | 2019-08-08 | ウォックハート リミテッド | 抗細菌組成物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000068229A2 (en) * | 1999-05-07 | 2000-11-16 | Wockhardt Limited | (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents |
ATE378335T1 (de) * | 2000-05-08 | 2007-11-15 | Wockhardt Ltd | Chirale fluorochinolizinon arginine salze |
WO2003099815A1 (en) * | 2002-05-28 | 2003-12-04 | Wockhardt Limited | Crystalline fluoroquinolone arginine salt form |
ATE366734T1 (de) | 2003-09-04 | 2007-08-15 | Wockhardt Ltd | Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat |
KR20130128483A (ko) * | 2006-03-07 | 2013-11-26 | 욱크하트 리미티드 | 벤조퀴놀리진-2-카르복실산의 프로드러그 |
-
2012
- 2012-01-06 RU RU2014115989/04A patent/RU2594166C2/ru active IP Right Revival
- 2012-01-06 CA CA2850159A patent/CA2850159A1/en not_active Abandoned
- 2012-01-06 JP JP2014532505A patent/JP6126102B2/ja active Active
- 2012-01-06 CN CN201280047235.5A patent/CN103842361A/zh active Pending
- 2012-01-06 EP EP12700532.0A patent/EP2776433A1/en not_active Withdrawn
- 2012-01-06 MX MX2014003770A patent/MX366887B/es active IP Right Grant
- 2012-01-06 US US14/240,400 patent/US20140296280A1/en not_active Abandoned
- 2012-01-06 AU AU2012313987A patent/AU2012313987B2/en not_active Ceased
- 2012-01-06 WO PCT/IB2012/050074 patent/WO2013046061A1/en active Application Filing
- 2012-01-06 KR KR1020147007356A patent/KR20140054307A/ko not_active Application Discontinuation
- 2012-01-06 BR BR112014006401A patent/BR112014006401A2/pt not_active Application Discontinuation
-
2014
- 2014-02-19 ZA ZA2014/01262A patent/ZA201401262B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013046061A1 (en) | 2013-04-04 |
CN103842361A (zh) | 2014-06-04 |
AU2012313987B2 (en) | 2016-11-24 |
EP2776433A1 (en) | 2014-09-17 |
JP2014527998A (ja) | 2014-10-23 |
NZ621358A (en) | 2016-03-31 |
KR20140054307A (ko) | 2014-05-08 |
CA2850159A1 (en) | 2013-04-04 |
US20140296280A1 (en) | 2014-10-02 |
RU2594166C2 (ru) | 2016-08-10 |
RU2014115989A (ru) | 2015-11-10 |
BR112014006401A2 (pt) | 2017-03-28 |
AU2012313987A1 (en) | 2014-03-06 |
JP6126102B2 (ja) | 2017-05-10 |
MX2014003770A (es) | 2014-04-30 |
ZA201401262B (en) | 2015-10-28 |
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