MX362246B - Metodo para el tratamiento de la sepsis en pacientes con niveles de albumina, colesterol y hdl por encima de los umbrales minimos. - Google Patents

Metodo para el tratamiento de la sepsis en pacientes con niveles de albumina, colesterol y hdl por encima de los umbrales minimos.

Info

Publication number
MX362246B
MX362246B MX2015007828A MX2015007828A MX362246B MX 362246 B MX362246 B MX 362246B MX 2015007828 A MX2015007828 A MX 2015007828A MX 2015007828 A MX2015007828 A MX 2015007828A MX 362246 B MX362246 B MX 362246B
Authority
MX
Mexico
Prior art keywords
cholesterol
albumin
patients
above minimum
hdl levels
Prior art date
Application number
MX2015007828A
Other languages
English (en)
Other versions
MX2015007828A (es
Inventor
M Levine Daniel
S Parker Thomas
R Gordon Bruce
D Saal Stuartd
Original Assignee
Sepsicure Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepsicure Llc filed Critical Sepsicure Llc
Publication of MX2015007828A publication Critical patent/MX2015007828A/es
Publication of MX362246B publication Critical patent/MX362246B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La invención se refiere a un método para tratar sepsis en sujetos que presentan niveles de albúmina en suero, y uno de niveles de colesterol total o HDL por encima de los valores de umbral mínimos. El método consiste en la administración intravenosa de una emulsión que contiene un fosfolípido, un lípido neutral y una sal de colato.
MX2015007828A 2012-12-18 2013-09-30 Metodo para el tratamiento de la sepsis en pacientes con niveles de albumina, colesterol y hdl por encima de los umbrales minimos. MX362246B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/718,246 US9023833B2 (en) 2012-12-18 2012-12-18 Method for treating sepsis in patients with albumin, cholesterol and HDL levels above minimum thresholds
PCT/US2013/062629 WO2014099089A1 (en) 2012-12-18 2013-09-30 Method for treating sepsis in patients with albumin, cholesterol and hdl levels above minimum thresholds

Publications (2)

Publication Number Publication Date
MX2015007828A MX2015007828A (es) 2015-08-20
MX362246B true MX362246B (es) 2019-01-09

Family

ID=50931609

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015007828A MX362246B (es) 2012-12-18 2013-09-30 Metodo para el tratamiento de la sepsis en pacientes con niveles de albumina, colesterol y hdl por encima de los umbrales minimos.

Country Status (26)

Country Link
US (1) US9023833B2 (es)
EP (1) EP2934152B1 (es)
JP (1) JP5963973B2 (es)
KR (1) KR20150069023A (es)
CN (1) CN104869830B (es)
AP (1) AP2015008443A0 (es)
AU (1) AU2013364214B2 (es)
CA (1) CA2892764C (es)
CY (1) CY1119851T1 (es)
DK (1) DK2934152T3 (es)
ES (1) ES2658418T3 (es)
HK (1) HK1214084A1 (es)
HR (1) HRP20180185T8 (es)
HU (1) HUE036041T2 (es)
IL (1) IL239060A0 (es)
LT (1) LT2934152T (es)
MX (1) MX362246B (es)
NO (1) NO3013861T3 (es)
NZ (1) NZ707550A (es)
PL (1) PL2934152T3 (es)
PT (1) PT2934152T (es)
RS (1) RS56840B1 (es)
RU (1) RU2571688C1 (es)
SI (1) SI2934152T1 (es)
UA (1) UA113231C2 (es)
WO (1) WO2014099089A1 (es)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344822A (en) 1992-08-12 1994-09-06 The Rogosin Institute Methods useful in endotoxin prophylaxis and therapy
US5674855A (en) * 1992-08-12 1997-10-07 The Rogosin Institute Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions
US5587366A (en) 1992-08-12 1996-12-24 The Rogosin Institute Compositions useful in prophylaxis and therapy of endotoxin related conditions
US6740487B1 (en) * 1999-06-10 2004-05-25 University Of Iowa Research Foundation Variant TLR4 nucleic acid and uses thereof
AU2001278864A1 (en) * 2000-06-30 2002-01-30 University Of Cincinnati Peptides with antioxidant and antimicrobial properties
JP4683740B2 (ja) * 2001-02-15 2011-05-18 明治乳業株式会社 炎症に伴う症状の軽減剤
WO2007027636A2 (en) 2005-08-29 2007-03-08 Sepsicure L.L.C. Method for treatment or prevention of conditions caused by gram-positive bacteria
WO2011050126A1 (en) * 2009-10-21 2011-04-28 University Of Medicine And Dentistry Of New Jersey Method for treating sepsis or septic shock

Also Published As

Publication number Publication date
CA2892764A1 (en) 2014-06-26
CN104869830B (zh) 2018-03-09
DK2934152T3 (en) 2018-01-15
KR20150069023A (ko) 2015-06-22
EP2934152A1 (en) 2015-10-28
EP2934152A4 (en) 2016-11-16
UA113231C2 (xx) 2016-12-26
IL239060A0 (en) 2015-07-30
HUE036041T2 (hu) 2018-06-28
WO2014099089A1 (en) 2014-06-26
AU2013364214A1 (en) 2015-05-21
JP5963973B2 (ja) 2016-08-03
CN104869830A (zh) 2015-08-26
ES2658418T3 (es) 2018-03-09
LT2934152T (lt) 2018-02-26
PT2934152T (pt) 2018-02-22
EP2934152B1 (en) 2017-11-08
RS56840B1 (sr) 2018-04-30
HRP20180185T1 (hr) 2018-03-09
NZ707550A (en) 2016-01-29
US9023833B2 (en) 2015-05-05
NO3013861T3 (es) 2018-04-28
US20140171391A1 (en) 2014-06-19
HK1214084A1 (zh) 2016-07-22
JP2016505575A (ja) 2016-02-25
HRP20180185T8 (hr) 2018-11-16
CA2892764C (en) 2015-11-24
AP2015008443A0 (en) 2015-05-31
PL2934152T3 (pl) 2018-07-31
AU2013364214B2 (en) 2015-11-05
CY1119851T1 (el) 2018-06-27
RU2571688C1 (ru) 2015-12-20
MX2015007828A (es) 2015-08-20
SI2934152T1 (en) 2018-05-31

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