MX359106B - Composicion farmaceutica inyectable de dexketoprofeno y tramadol. - Google Patents
Composicion farmaceutica inyectable de dexketoprofeno y tramadol.Info
- Publication number
- MX359106B MX359106B MX2014013083A MX2014013083A MX359106B MX 359106 B MX359106 B MX 359106B MX 2014013083 A MX2014013083 A MX 2014013083A MX 2014013083 A MX2014013083 A MX 2014013083A MX 359106 B MX359106 B MX 359106B
- Authority
- MX
- Mexico
- Prior art keywords
- dexketoprofen
- tramadol
- pharmaceutical composition
- injectable pharmaceutical
- composition
- Prior art date
Links
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 title abstract 3
- DKYWVDODHFEZIM-NSHDSACASA-N dexketoprofen Chemical group OC(=O)[C@@H](C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-NSHDSACASA-N 0.000 title abstract 3
- 229960002783 dexketoprofen Drugs 0.000 title abstract 3
- 229960004380 tramadol Drugs 0.000 title abstract 3
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000008215 water for injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica inyectable de dexketoprofeno y tramadol como principios activos. En particular, se trata de una solución de dexketoprofeno y tramadol en una mezcla de agua para inyección y al menos un cosolvente. La presente invención también se refiere a un procedimiento para la preparación de dicha composición, a una forma farmacéutica de dosificación unitaria que la contiene y a su uso para el tratamiento del dolor de intensidad moderado a severo, inflamación y/o fiebre.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201200450A ES2432222B1 (es) | 2012-04-30 | 2012-04-30 | Composición farmacéutica inyectable de dexketoprofeno y tramadol |
PCT/ES2013/000106 WO2013164498A1 (es) | 2012-04-30 | 2013-04-29 | Composición farmacéutica inyectable de dexketoprofeno y tramadol |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014013083A MX2014013083A (es) | 2015-04-14 |
MX359106B true MX359106B (es) | 2018-09-14 |
Family
ID=49514233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014013083A MX359106B (es) | 2012-04-30 | 2013-04-29 | Composicion farmaceutica inyectable de dexketoprofeno y tramadol. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2857016B1 (es) |
BR (1) | BR112014027002A2 (es) |
CO (1) | CO7170180A2 (es) |
ES (1) | ES2432222B1 (es) |
MX (1) | MX359106B (es) |
RU (1) | RU2660356C2 (es) |
WO (1) | WO2013164498A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3928766A1 (en) | 2020-06-26 | 2021-12-29 | Usso Barnas | Pharmaceutical composition and use thereof |
EP4188337A1 (en) * | 2020-07-31 | 2023-06-07 | KRKA, d.d., Novo mesto | Formulation containing dexketoprofen and tramadol and method for making the same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1546478A (fr) | 1967-01-27 | 1968-11-22 | Rhone Poulenc Sa | Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation |
US3652589A (en) | 1967-07-27 | 1972-03-28 | Gruenenthal Chemie | 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols |
AU661723B2 (en) * | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
CN1204891C (zh) * | 2001-12-27 | 2005-06-08 | 沈阳药科大学 | 一种含有曲马多的注射液及其应用 |
US7090859B2 (en) * | 2002-12-13 | 2006-08-15 | Ronald Thomas Haas | Ketoprofen compositions and methods of making them |
WO2006116626A2 (en) * | 2005-04-28 | 2006-11-02 | Theraquest Biosciences Llc | Methods and compositions for treating pain |
BRPI0700133A (pt) | 2007-01-29 | 2008-09-16 | Incrementha P D & I Pesquisa D | composição farmacêutica compreendendo tramadol e cetoprofeno em combinação |
WO2008150324A1 (en) * | 2007-03-26 | 2008-12-11 | Theraquest Biosciences, Inc. | Subanalgesic doses of drug combinations |
-
2012
- 2012-04-30 ES ES201200450A patent/ES2432222B1/es active Active
-
2013
- 2013-04-29 BR BR112014027002A patent/BR112014027002A2/pt not_active IP Right Cessation
- 2013-04-29 MX MX2014013083A patent/MX359106B/es active IP Right Grant
- 2013-04-29 WO PCT/ES2013/000106 patent/WO2013164498A1/es active Application Filing
- 2013-04-29 RU RU2014148062A patent/RU2660356C2/ru active
- 2013-04-29 EP EP13784325.6A patent/EP2857016B1/en active Active
-
2014
- 2014-10-28 CO CO14238802A patent/CO7170180A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
ES2432222A1 (es) | 2013-12-02 |
BR112014027002A2 (pt) | 2017-06-27 |
RU2014148062A (ru) | 2016-06-27 |
ES2432222B1 (es) | 2014-06-10 |
CO7170180A2 (es) | 2015-01-28 |
EP2857016A4 (en) | 2015-12-23 |
WO2013164498A1 (es) | 2013-11-07 |
EP2857016A1 (en) | 2015-04-08 |
MX2014013083A (es) | 2015-04-14 |
RU2660356C2 (ru) | 2018-07-05 |
EP2857016B1 (en) | 2017-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |