MX359084B - Péptidos antimicrobianos. - Google Patents
Péptidos antimicrobianos.Info
- Publication number
- MX359084B MX359084B MX2014010655A MX2014010655A MX359084B MX 359084 B MX359084 B MX 359084B MX 2014010655 A MX2014010655 A MX 2014010655A MX 2014010655 A MX2014010655 A MX 2014010655A MX 359084 B MX359084 B MX 359084B
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- antimicrobial peptides
- ter2
- ter1
- fungi
- Prior art date
Links
- 102000044503 Antimicrobial Peptides Human genes 0.000 title abstract 2
- 108700042778 Antimicrobial Peptides Proteins 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000003910 polypeptide antibiotic agent Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/98—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving alcohol, e.g. ethanol in breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1729—Cationic antimicrobial peptides, e.g. defensins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Virology (AREA)
Abstract
La presente invención se refiere a un nuevo péptido antimicrobiano, que presenta al menos ocho aminoácidos sucesivos, teniendo el péptido una secuencia con la siguiente fórmula: Ter1-X1-B1-X2-B2-X3-Z1-Z2-X4-Ter2. El péptido puede presentar además también extremos terminales modificados. El péptido es eficaz para el tratamiento o la prevención de enfermedades inflamatorias e infecciosas, que se provocan por microorganismos, tales como bacterias u hongos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102012203547A DE102012203547A1 (de) | 2012-03-07 | 2012-03-07 | Antimikrobielle Peptide |
PCT/EP2013/054599 WO2013132005A1 (de) | 2012-03-07 | 2013-03-07 | Antimikrobielle peptide |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014010655A MX2014010655A (es) | 2015-03-06 |
MX359084B true MX359084B (es) | 2018-09-03 |
Family
ID=47710149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014010655A MX359084B (es) | 2012-03-07 | 2013-03-07 | Péptidos antimicrobianos. |
Country Status (12)
Country | Link |
---|---|
US (2) | US20150087579A1 (es) |
EP (1) | EP2822958B1 (es) |
JP (2) | JP6157514B2 (es) |
KR (1) | KR20140142700A (es) |
CN (2) | CN108822201A (es) |
AU (1) | AU2013229486B2 (es) |
CA (1) | CA2866520C (es) |
CL (1) | CL2014002180A1 (es) |
DE (1) | DE102012203547A1 (es) |
MX (1) | MX359084B (es) |
RU (1) | RU2660351C2 (es) |
WO (1) | WO2013132005A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102012203547A1 (de) * | 2012-03-07 | 2013-09-12 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Antimikrobielle Peptide |
KR101804847B1 (ko) | 2014-10-27 | 2017-12-07 | 경희대학교 산학협력단 | 항균 펩타이드 헥사머를 포함하는 구강 질환 예방 및 치료용 약학적 조성물 및 이의 용도 |
AU2016287754B2 (en) | 2015-07-02 | 2021-02-25 | Dana-Farber Cancer Institute, Inc. | Stabilized anti-microbial peptides |
EP3423075B1 (en) | 2016-02-29 | 2024-04-03 | Dana-Farber Cancer Institute, Inc. | Stapled intracellular-targeting antimicrobial peptides to treat infection |
FR3052453B1 (fr) * | 2016-06-14 | 2018-05-18 | Sederma | Peptide, composition le comprenant et utilisations notamment cosmetiques |
JP7305614B2 (ja) | 2017-07-19 | 2023-07-10 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 抗生物質耐性細菌感染症の処置のための安定化抗菌ペプチド |
KR102558956B1 (ko) * | 2019-12-30 | 2023-07-24 | 주식회사 아이젤 | 양친매성 펩타이드 및 이를 포함하는 항균용 또는 항염증용 조성물 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001027143A1 (en) * | 1999-10-12 | 2001-04-19 | Blis Technologies Limited | Lantibiotic |
AU2003215257A1 (en) * | 2002-02-19 | 2003-09-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | Modified defensins and their use |
CN1183960C (zh) * | 2003-02-27 | 2005-01-12 | 四川大学 | 双歧杆菌细胞壁蛋白在制药中的应用 |
US8071285B1 (en) * | 2003-05-14 | 2011-12-06 | Carl Henry Lawyer | Zinc finger protein derivatives and methods of using same |
KR20090111307A (ko) * | 2006-07-03 | 2009-10-26 | 엑손히트 써라퓨틱스 에스에이 | 전립선 특이적 전사물 및 전립선암의 치료 및 진단에 사용되는 이의 용도 |
RU2468033C2 (ru) * | 2006-07-10 | 2012-11-27 | Пба3 БиоМед ГмбХ | Антибактериальные пептиды |
EP2077274A1 (en) * | 2008-01-02 | 2009-07-08 | Ceinge Biotecnologie Avanzate s.c. a r.l. | Synthetic analogs of human beta-defensins having antimicrobial, antiviral and chemotactic activity |
CA2711807A1 (en) * | 2008-01-08 | 2009-07-16 | Akthelia Pharmaceuticals | Agonists for antimicrobial peptide systems |
US20090298707A1 (en) * | 2008-03-18 | 2009-12-03 | The Regents Of The University Of California | Sparse matrix system and method for identification of specific ligands or targets |
DE102010040153A1 (de) * | 2010-09-02 | 2012-03-08 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Stoffkombination zur Behandlung von entzündlichen oder infektiösen Erkrankungen |
DE102012203547A1 (de) * | 2012-03-07 | 2013-09-12 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Antimikrobielle Peptide |
-
2012
- 2012-03-07 DE DE102012203547A patent/DE102012203547A1/de not_active Withdrawn
-
2013
- 2013-03-07 CN CN201810643582.3A patent/CN108822201A/zh active Pending
- 2013-03-07 JP JP2014560374A patent/JP6157514B2/ja not_active Expired - Fee Related
- 2013-03-07 WO PCT/EP2013/054599 patent/WO2013132005A1/de active Application Filing
- 2013-03-07 KR KR1020147025281A patent/KR20140142700A/ko active Search and Examination
- 2013-03-07 RU RU2014140231A patent/RU2660351C2/ru not_active IP Right Cessation
- 2013-03-07 AU AU2013229486A patent/AU2013229486B2/en not_active Ceased
- 2013-03-07 CA CA2866520A patent/CA2866520C/en not_active Expired - Fee Related
- 2013-03-07 US US14/383,549 patent/US20150087579A1/en not_active Abandoned
- 2013-03-07 MX MX2014010655A patent/MX359084B/es active IP Right Grant
- 2013-03-07 CN CN201380012350.3A patent/CN104245721A/zh active Pending
- 2013-03-07 EP EP13708150.1A patent/EP2822958B1/de active Active
-
2014
- 2014-08-14 CL CL2014002180A patent/CL2014002180A1/es unknown
-
2016
- 2016-11-23 US US15/360,556 patent/US20170073371A1/en not_active Abandoned
-
2017
- 2017-02-28 JP JP2017035914A patent/JP2017148045A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2014010655A (es) | 2015-03-06 |
RU2014140231A (ru) | 2016-04-27 |
DE102012203547A1 (de) | 2013-09-12 |
US20150087579A1 (en) | 2015-03-26 |
AU2013229486A1 (en) | 2014-10-23 |
CA2866520C (en) | 2019-05-21 |
EP2822958A1 (de) | 2015-01-14 |
AU2013229486B2 (en) | 2017-10-19 |
CL2014002180A1 (es) | 2015-04-17 |
JP6157514B2 (ja) | 2017-07-05 |
JP2015510874A (ja) | 2015-04-13 |
RU2660351C2 (ru) | 2018-07-05 |
WO2013132005A1 (de) | 2013-09-12 |
CN108822201A (zh) | 2018-11-16 |
EP2822958B1 (de) | 2018-12-19 |
JP2017148045A (ja) | 2017-08-31 |
CN104245721A (zh) | 2014-12-24 |
KR20140142700A (ko) | 2014-12-12 |
CA2866520A1 (en) | 2013-09-12 |
US20170073371A1 (en) | 2017-03-16 |
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Legal Events
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FG | Grant or registration |