MX345333B - Biomarcadores de envejecimiento cardiaco y métodos de uso. - Google Patents
Biomarcadores de envejecimiento cardiaco y métodos de uso.Info
- Publication number
- MX345333B MX345333B MX2012005355A MX2012005355A MX345333B MX 345333 B MX345333 B MX 345333B MX 2012005355 A MX2012005355 A MX 2012005355A MX 2012005355 A MX2012005355 A MX 2012005355A MX 345333 B MX345333 B MX 345333B
- Authority
- MX
- Mexico
- Prior art keywords
- heart
- methods
- aging
- biomarkers
- heart aging
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un conjunto de biomarcadores resistentes al envejecimiento en el corazón que comprenden muchos genes involucrados en el trayecto de señalización Wnt. Se ha encontrado que estos genes se regulan hacia abajo en tejido de corazones viejos contra jóvenes. Se describen los métodos de uso de estos biomarcadores para monitorear el envejecimiento cardiaco y para identificar los nutrientes y regímenes dietéticos para retardar el envejecimiento cardiaco. Se describen los métodos para la modulación de los mismos genes para retardar el envejecimiento cardiaco.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28087909P | 2009-11-10 | 2009-11-10 | |
PCT/US2010/002950 WO2011059490A1 (en) | 2009-11-10 | 2010-11-09 | Heart aging biomarkers and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012005355A MX2012005355A (es) | 2012-05-29 |
MX345333B true MX345333B (es) | 2017-01-25 |
Family
ID=43991901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012005355A MX345333B (es) | 2009-11-10 | 2010-11-09 | Biomarcadores de envejecimiento cardiaco y métodos de uso. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20120220488A1 (es) |
EP (1) | EP2499260B1 (es) |
JP (1) | JP5901530B2 (es) |
CN (1) | CN102695807B (es) |
AU (1) | AU2010318703B2 (es) |
BR (1) | BR112012011133A2 (es) |
CA (1) | CA2779606A1 (es) |
ES (1) | ES2641491T3 (es) |
IN (1) | IN2012DN03954A (es) |
MX (1) | MX345333B (es) |
RU (1) | RU2562174C2 (es) |
WO (1) | WO2011059490A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9255296B2 (en) * | 2011-02-24 | 2016-02-09 | Hill's Pet Nutrition, Inc. | Compositions and methods for diagnosing and treating kidney disorders in a feline |
CN105868532B (zh) * | 2016-03-22 | 2019-03-05 | 曾金生 | 一种智能评估心脏衰老程度的方法及系统 |
US20180144820A1 (en) | 2016-10-24 | 2018-05-24 | Habit, Llc | System and method for implementing meal selection based on vitals, genotype and phenotype |
CN110157788A (zh) * | 2019-04-04 | 2019-08-23 | 东莞市第八人民医院(东莞市儿童医院) | 一种用于定量检测SENP2 mRNA水平的引物、探针和试剂盒 |
CN111366736A (zh) * | 2020-03-31 | 2020-07-03 | 中国科学院昆明动物研究所 | 指征健康衰老关键通路的血清蛋白质标志物及应用 |
US20220208347A1 (en) * | 2020-12-29 | 2022-06-30 | Kpn Innovations, Llc. | Systems and methods for generating a body degradation reduction program |
US11139064B1 (en) * | 2020-12-29 | 2021-10-05 | Kpn Innovations, Llc. | Systems and methods for generating a body degradation reduction program |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2112543C1 (ru) * | 1996-09-26 | 1998-06-10 | Александр Григорьевич Хоменко | Иммуномодулирующее лекарственное средство |
WO2001012851A2 (en) * | 1999-08-12 | 2001-02-22 | Wisconsin Alumni Research Foundation | Identification of genetic markers of biological age and metabolism |
AU2461201A (en) | 1999-12-23 | 2001-07-03 | Regents Of The University Of California, The | Interventions to mimic the effects of calorie restriction |
US6406853B1 (en) | 1999-12-23 | 2002-06-18 | The Regents Of The University Of California | Interventions to mimic the effects of calorie restriction |
DK1549353T3 (da) * | 2002-10-09 | 2010-07-12 | Central Iowa Health System | Anvendelse af alfa(1,3)galactosyltransferaseudtrykkende allogene tumorceller til vaccination mod tumorer |
US20040191775A1 (en) | 2003-03-12 | 2004-09-30 | Spindler Stephen R. | Methods of analyzing genes affected by caloric restriction or caloric restriction mimetics |
US20050013776A1 (en) | 2003-07-16 | 2005-01-20 | Spindler Stephen R. | Methods of evaluating the dynamics of caloric restriction and identifying caloric restriction mimetics |
US20040180003A1 (en) | 2003-03-12 | 2004-09-16 | Spindler Stephen R. | Methods of screening for caloric restriction mimetics and reproducing effects of caloric restriction |
AU2004253579B2 (en) * | 2003-07-01 | 2010-12-23 | Biomol International L.P. | Sirt1 modulators for manipulating cells/organism lifespan/stress response |
DK2620510T4 (da) * | 2005-06-15 | 2020-03-30 | Complete Genomics Inc | Enkeltmolekyle-arrays til genetisk og kemisk analyse |
US20070196850A1 (en) * | 2006-01-27 | 2007-08-23 | University Of Washington | Identification of aging genes through large-scale analysis |
MX2008009574A (es) | 2006-02-01 | 2008-09-04 | Nestec Sa | Sistema y metodos nutricionales para aumentar la longevidad. |
US20100129915A1 (en) * | 2006-11-09 | 2010-05-27 | Deepak Srivastava | Methods for inducing cardiomyogenesis |
US20110033430A1 (en) * | 2007-02-09 | 2011-02-10 | The General Hospital Corporation | Methods for the induction of a cell to enter the islet 1+ lineage and a method for the expansion thereof |
JP5620275B2 (ja) * | 2008-01-14 | 2014-11-05 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | 超増殖性疾患及び脈管形成に関連する疾病を処理するために有用なスルホン置換された2,3−ジヒドロイミダゾ[1,2−c]キナゾリン誘導体類 |
-
2010
- 2010-11-09 EP EP10830319.9A patent/EP2499260B1/en active Active
- 2010-11-09 AU AU2010318703A patent/AU2010318703B2/en not_active Ceased
- 2010-11-09 US US13/505,912 patent/US20120220488A1/en not_active Abandoned
- 2010-11-09 JP JP2012537864A patent/JP5901530B2/ja active Active
- 2010-11-09 ES ES10830319.9T patent/ES2641491T3/es active Active
- 2010-11-09 CA CA2779606A patent/CA2779606A1/en not_active Abandoned
- 2010-11-09 CN CN201080060948.6A patent/CN102695807B/zh not_active Expired - Fee Related
- 2010-11-09 WO PCT/US2010/002950 patent/WO2011059490A1/en active Application Filing
- 2010-11-09 MX MX2012005355A patent/MX345333B/es active IP Right Grant
- 2010-11-09 BR BR112012011133A patent/BR112012011133A2/pt not_active IP Right Cessation
- 2010-11-09 RU RU2012123990/10A patent/RU2562174C2/ru not_active IP Right Cessation
-
2012
- 2012-05-04 IN IN3954DEN2012 patent/IN2012DN03954A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN102695807B (zh) | 2016-02-24 |
AU2010318703B2 (en) | 2016-08-25 |
JP5901530B2 (ja) | 2016-04-13 |
RU2012123990A (ru) | 2013-12-20 |
IN2012DN03954A (es) | 2015-08-07 |
EP2499260B1 (en) | 2017-08-23 |
CA2779606A1 (en) | 2011-05-19 |
EP2499260A1 (en) | 2012-09-19 |
MX2012005355A (es) | 2012-05-29 |
WO2011059490A1 (en) | 2011-05-19 |
RU2562174C2 (ru) | 2015-09-10 |
EP2499260A4 (en) | 2013-07-17 |
JP2013509877A (ja) | 2013-03-21 |
CN102695807A (zh) | 2012-09-26 |
AU2010318703A1 (en) | 2012-05-31 |
US20120220488A1 (en) | 2012-08-30 |
BR112012011133A2 (pt) | 2016-07-05 |
ES2641491T3 (es) | 2017-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2012005355A (es) | Biomarcadores de envejecimiento cardiaco y metodos de uso. | |
IL254909B (en) | Preparations and methods for treating edible material and their substrates | |
IL248530A0 (en) | Biomarkers and treatment methods | |
IL242842A (en) | Methods for detecting and diagnosing cardiac arrhythmias | |
HRP20171352T1 (hr) | Wnt-antagonisti i postupci liječenja | |
EP2614369A4 (en) | HEMMER OF HUMAN EZH2 AND METHOD FOR THEIR USE | |
HK1205938A1 (en) | Inhibitors of human ezh2, and methods of use thereof ezh2 | |
EP2611822A4 (en) | COMPOSITIONS FOR IDENTIFICATION OF NERVES AND METHOD FOR THEIR USE | |
EP2569633A4 (en) | COMPOSITIONS AND METHOD FOR IDENTIFYING TUMOR-SPECIFIC NEOANTIGENE | |
EP2633046A4 (en) | COMPOSITIONS AND METHODS FOR INHIBITING PCSK9 GENES | |
EP2542060A4 (en) | COMPOSITIONS AND METHODS FOR TREATMENT AND / OR PREVENTION OF CARDIOVASCULAR DISEASES | |
EP2418943A4 (en) | CURCUMIN ANALOGUES AS DOUBLE JAK2 / STAT3 INHIBITORS AND METHODS FOR THE PREPARATION AND USE THEREOF | |
HK1178074A1 (en) | Compositions and methods for the diagnosis and treatment of tumor | |
HK1208702A1 (en) | Compositions and methods for modulation of fgfr3 expression fgfr3 | |
IL220290A0 (en) | Stem cell immune modulation methods of use and apparatus | |
HK1202243A1 (en) | Methods for improving cognitive function and decreasing heart rate | |
EP2164978A4 (en) | COMPOSITIONS AND METHODS FOR MODULATING ADAMTS13 ACTIVITY | |
IL225793A0 (en) | Methods and preparations for curing insulin-related medical conditions | |
IL240560A0 (en) | Preparations and methods for tumor diagnosis and treatment | |
EP2596349A4 (en) | PROCEDURE FOR DETECTING CARDIOVASCULAR DISEASES OR SUFFERING | |
HK1206631A1 (en) | Methods and compositions for treatment of traumatic brain injury and for modulation of migration of neurogenic cells | |
EP2403518A4 (en) | Compositions and methods for modulating cell migration | |
HK1258467A1 (zh) | 用於預防和治療心臟肥大的方法和組合物 | |
HK1212212A1 (en) | Compositions and methods for inhibiting activity of hypoxia-inducible transcription factor complex and its use for treatment of tumors | |
IL224632A (en) | Fentanyl docushexanavate and its use in the treatment and prevention of cardiovascular disease |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |