MX345333B - Biomarcadores de envejecimiento cardiaco y métodos de uso. - Google Patents

Biomarcadores de envejecimiento cardiaco y métodos de uso.

Info

Publication number
MX345333B
MX345333B MX2012005355A MX2012005355A MX345333B MX 345333 B MX345333 B MX 345333B MX 2012005355 A MX2012005355 A MX 2012005355A MX 2012005355 A MX2012005355 A MX 2012005355A MX 345333 B MX345333 B MX 345333B
Authority
MX
Mexico
Prior art keywords
heart
methods
aging
biomarkers
heart aging
Prior art date
Application number
MX2012005355A
Other languages
English (en)
Other versions
MX2012005355A (es
Inventor
Li Quinghong
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of MX2012005355A publication Critical patent/MX2012005355A/es
Publication of MX345333B publication Critical patent/MX345333B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un conjunto de biomarcadores resistentes al envejecimiento en el corazón que comprenden muchos genes involucrados en el trayecto de señalización Wnt. Se ha encontrado que estos genes se regulan hacia abajo en tejido de corazones viejos contra jóvenes. Se describen los métodos de uso de estos biomarcadores para monitorear el envejecimiento cardiaco y para identificar los nutrientes y regímenes dietéticos para retardar el envejecimiento cardiaco. Se describen los métodos para la modulación de los mismos genes para retardar el envejecimiento cardiaco.
MX2012005355A 2009-11-10 2010-11-09 Biomarcadores de envejecimiento cardiaco y métodos de uso. MX345333B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28087909P 2009-11-10 2009-11-10
PCT/US2010/002950 WO2011059490A1 (en) 2009-11-10 2010-11-09 Heart aging biomarkers and methods of use

Publications (2)

Publication Number Publication Date
MX2012005355A MX2012005355A (es) 2012-05-29
MX345333B true MX345333B (es) 2017-01-25

Family

ID=43991901

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012005355A MX345333B (es) 2009-11-10 2010-11-09 Biomarcadores de envejecimiento cardiaco y métodos de uso.

Country Status (12)

Country Link
US (1) US20120220488A1 (es)
EP (1) EP2499260B1 (es)
JP (1) JP5901530B2 (es)
CN (1) CN102695807B (es)
AU (1) AU2010318703B2 (es)
BR (1) BR112012011133A2 (es)
CA (1) CA2779606A1 (es)
ES (1) ES2641491T3 (es)
IN (1) IN2012DN03954A (es)
MX (1) MX345333B (es)
RU (1) RU2562174C2 (es)
WO (1) WO2011059490A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9255296B2 (en) * 2011-02-24 2016-02-09 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and treating kidney disorders in a feline
CN105868532B (zh) * 2016-03-22 2019-03-05 曾金生 一种智能评估心脏衰老程度的方法及系统
US20180144820A1 (en) 2016-10-24 2018-05-24 Habit, Llc System and method for implementing meal selection based on vitals, genotype and phenotype
CN110157788A (zh) * 2019-04-04 2019-08-23 东莞市第八人民医院（东莞市儿童医院） 一种用于定量检测SENP2 mRNA水平的引物、探针和试剂盒
CN111366736A (zh) * 2020-03-31 2020-07-03 中国科学院昆明动物研究所 指征健康衰老关键通路的血清蛋白质标志物及应用
US20220208347A1 (en) * 2020-12-29 2022-06-30 Kpn Innovations, Llc. Systems and methods for generating a body degradation reduction program
US11139064B1 (en) * 2020-12-29 2021-10-05 Kpn Innovations, Llc. Systems and methods for generating a body degradation reduction program

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2112543C1 (ru) * 1996-09-26 1998-06-10 Александр Григорьевич Хоменко Иммуномодулирующее лекарственное средство
WO2001012851A2 (en) * 1999-08-12 2001-02-22 Wisconsin Alumni Research Foundation Identification of genetic markers of biological age and metabolism
AU2461201A (en) 1999-12-23 2001-07-03 Regents Of The University Of California, The Interventions to mimic the effects of calorie restriction
US6406853B1 (en) 1999-12-23 2002-06-18 The Regents Of The University Of California Interventions to mimic the effects of calorie restriction
DK1549353T3 (da) * 2002-10-09 2010-07-12 Central Iowa Health System Anvendelse af alfa(1,3)galactosyltransferaseudtrykkende allogene tumorceller til vaccination mod tumorer
US20040191775A1 (en) 2003-03-12 2004-09-30 Spindler Stephen R. Methods of analyzing genes affected by caloric restriction or caloric restriction mimetics
US20050013776A1 (en) 2003-07-16 2005-01-20 Spindler Stephen R. Methods of evaluating the dynamics of caloric restriction and identifying caloric restriction mimetics
US20040180003A1 (en) 2003-03-12 2004-09-16 Spindler Stephen R. Methods of screening for caloric restriction mimetics and reproducing effects of caloric restriction
AU2004253579B2 (en) * 2003-07-01 2010-12-23 Biomol International L.P. Sirt1 modulators for manipulating cells/organism lifespan/stress response
DK2620510T4 (da) * 2005-06-15 2020-03-30 Complete Genomics Inc Enkeltmolekyle-arrays til genetisk og kemisk analyse
US20070196850A1 (en) * 2006-01-27 2007-08-23 University Of Washington Identification of aging genes through large-scale analysis
MX2008009574A (es) 2006-02-01 2008-09-04 Nestec Sa Sistema y metodos nutricionales para aumentar la longevidad.
US20100129915A1 (en) * 2006-11-09 2010-05-27 Deepak Srivastava Methods for inducing cardiomyogenesis
US20110033430A1 (en) * 2007-02-09 2011-02-10 The General Hospital Corporation Methods for the induction of a cell to enter the islet 1+ lineage and a method for the expansion thereof
JP5620275B2 (ja) * 2008-01-14 2014-11-05 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 超増殖性疾患及び脈管形成に関連する疾病を処理するために有用なスルホン置換された２，３−ジヒドロイミダゾ［１，２−ｃ］キナゾリン誘導体類

Also Published As

Publication number Publication date
CN102695807B (zh) 2016-02-24
AU2010318703B2 (en) 2016-08-25
JP5901530B2 (ja) 2016-04-13
RU2012123990A (ru) 2013-12-20
IN2012DN03954A (es) 2015-08-07
EP2499260B1 (en) 2017-08-23
CA2779606A1 (en) 2011-05-19
EP2499260A1 (en) 2012-09-19
MX2012005355A (es) 2012-05-29
WO2011059490A1 (en) 2011-05-19
RU2562174C2 (ru) 2015-09-10
EP2499260A4 (en) 2013-07-17
JP2013509877A (ja) 2013-03-21
CN102695807A (zh) 2012-09-26
AU2010318703A1 (en) 2012-05-31
US20120220488A1 (en) 2012-08-30
BR112012011133A2 (pt) 2016-07-05
ES2641491T3 (es) 2017-11-10

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