MX337606B - Metodo y composiciones farmaceuticas para el tratamiento de la hiperglicemia postprandial de la diabetes tipo ii, a traves de la mucosa bucal. - Google Patents
Metodo y composiciones farmaceuticas para el tratamiento de la hiperglicemia postprandial de la diabetes tipo ii, a traves de la mucosa bucal.Info
- Publication number
- MX337606B MX337606B MX2012000466A MX2012000466A MX337606B MX 337606 B MX337606 B MX 337606B MX 2012000466 A MX2012000466 A MX 2012000466A MX 2012000466 A MX2012000466 A MX 2012000466A MX 337606 B MX337606 B MX 337606B
- Authority
- MX
- Mexico
- Prior art keywords
- diabetes
- type
- trans
- buccal mucosa
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a un método y una composición farmacéutica en forma de una solución hidroalcohólica en la cual se disuelve de forma estable y completa al menos un principio activo hipoglicemiante/insulinotropo a una dosis reducida en 30 a 50% con relación a la dosis unitaria usual para vía oral, para su aplicación a través de la mucosa bucal en el tratamiento puntual de la HiperGlicemia Post-Prandial de la Diabetes de Tipo II en humanos o animales. La invención se relaciona igualmente con un método de preparación de esta formulación y a su uso específico para el tratamiento puntual de la HiperGlicemia PostPrandial (HGPP) en el contexto de la Diabetes de Tipo II.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0954819A FR2947729B1 (fr) | 2009-07-10 | 2009-07-10 | Composition pharmaceutique pour le traitement du diabete de type ii par voie trans-muqueuse buccale |
PCT/FR2010/051426 WO2011004117A1 (fr) | 2009-07-10 | 2010-07-07 | Procédé et compositions pharmaceutiques pour le traitement de l'hyper glycémie post-prandiale du diabète de type ii par voie trans-muqueuse buccale |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012000466A MX2012000466A (es) | 2012-04-19 |
MX337606B true MX337606B (es) | 2016-03-10 |
Family
ID=41571558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012000466A MX337606B (es) | 2009-07-10 | 2010-07-07 | Metodo y composiciones farmaceuticas para el tratamiento de la hiperglicemia postprandial de la diabetes tipo ii, a traves de la mucosa bucal. |
Country Status (10)
Country | Link |
---|---|
US (1) | US9161910B2 (es) |
EP (1) | EP2451436A1 (es) |
JP (1) | JP2012532852A (es) |
CN (1) | CN102481254A (es) |
BR (1) | BR112012000596A2 (es) |
FR (1) | FR2947729B1 (es) |
IN (1) | IN2012DN00977A (es) |
MX (1) | MX337606B (es) |
RU (1) | RU2543635C2 (es) |
WO (1) | WO2011004117A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2940116B1 (fr) * | 2008-12-22 | 2012-07-06 | Philippe Perovitch | Formulation pour l'administration d'hypolipemiant par voie trans-muqueuse buccale |
FR3000896B1 (fr) * | 2013-01-14 | 2016-08-26 | Philippe Perovitch | Forme galenique pour l'administration de principe(s) actif(s) permettant l'induction acceleree du sommeil et/ou le traitement des troubles du sommeil |
FR3031668A1 (fr) | 2015-01-20 | 2016-07-22 | Philippe Perovitch | Dispositif d'administration d'un principe actif par voie per-muqueuse buccale. |
FR3053244A1 (fr) | 2016-07-01 | 2018-01-05 | Philippe Perovitch | Dispositif d'administration d'au moins un principe actif par voie per-muqueuse buccale. |
CN107669683B (zh) * | 2017-09-30 | 2020-07-03 | 杭州华东医药集团新药研究院有限公司 | 含有西格列汀与二甲双胍的药物组合物 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2071779C1 (ru) * | 1993-05-12 | 1997-01-20 | Хабаровский химико-фармацевтический завод | Способ получения пантокрина для инъекций |
US20030095925A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
US6451286B1 (en) * | 1998-12-21 | 2002-09-17 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds |
US20030087820A1 (en) * | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
US20030235595A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent |
US7411089B2 (en) * | 2002-04-15 | 2008-08-12 | Ajinomoto Co., Inc. | Nateglinide crystals |
SE528866C2 (sv) * | 2005-07-01 | 2007-02-27 | Volvo Lastvagnar Ab | Anordning för att kontrollera höjden hos en last eller lastbärare bakom förarhytten hos en lastbil |
CA2617495A1 (en) * | 2005-08-30 | 2007-03-08 | Abbott Laboratories | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv) |
DE102006027790A1 (de) * | 2006-06-16 | 2007-12-20 | Lts Lohmann Therapie-Systeme Ag | Typ-2-Diabetes Kombinations-Wafer |
US20080031959A1 (en) * | 2006-07-28 | 2008-02-07 | Blondino Frank E | Anti-migraine oral spray formulations and methods |
FR2906140B1 (fr) | 2006-09-22 | 2008-12-05 | Philippe Perovitch | Forme galenique pour l'administration par voie trans-muqueuse de principes actifs |
-
2009
- 2009-07-10 FR FR0954819A patent/FR2947729B1/fr not_active Expired - Fee Related
-
2010
- 2010-07-07 CN CN2010800381696A patent/CN102481254A/zh active Pending
- 2010-07-07 EP EP10742210A patent/EP2451436A1/fr not_active Withdrawn
- 2010-07-07 US US13/383,101 patent/US9161910B2/en not_active Expired - Fee Related
- 2010-07-07 IN IN977DEN2012 patent/IN2012DN00977A/en unknown
- 2010-07-07 MX MX2012000466A patent/MX337606B/es active IP Right Grant
- 2010-07-07 JP JP2012519040A patent/JP2012532852A/ja active Pending
- 2010-07-07 RU RU2012104639/15A patent/RU2543635C2/ru not_active IP Right Cessation
- 2010-07-07 WO PCT/FR2010/051426 patent/WO2011004117A1/fr active Application Filing
- 2010-07-07 BR BR112012000596A patent/BR112012000596A2/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2012104639A (ru) | 2013-08-20 |
RU2543635C2 (ru) | 2015-03-10 |
IN2012DN00977A (es) | 2015-04-10 |
FR2947729B1 (fr) | 2012-01-20 |
WO2011004117A1 (fr) | 2011-01-13 |
JP2012532852A (ja) | 2012-12-20 |
MX2012000466A (es) | 2012-04-19 |
BR112012000596A2 (pt) | 2016-02-10 |
CN102481254A (zh) | 2012-05-30 |
FR2947729A1 (fr) | 2011-01-14 |
EP2451436A1 (fr) | 2012-05-16 |
US9161910B2 (en) | 2015-10-20 |
US20120190618A1 (en) | 2012-07-26 |
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Legal Events
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FG | Grant or registration |