MX337307B - Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma. - Google Patents

Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma.

Info

Publication number
MX337307B
MX337307B MX2013003000A MX2013003000A MX337307B MX 337307 B MX337307 B MX 337307B MX 2013003000 A MX2013003000 A MX 2013003000A MX 2013003000 A MX2013003000 A MX 2013003000A MX 337307 B MX337307 B MX 337307B
Authority
MX
Mexico
Prior art keywords
lipolytic enzyme
polynucleotides encoding
encoding same
improved stability
enzyme variant
Prior art date
Application number
MX2013003000A
Other languages
English (en)
Inventor
Allan Svendsen
Jesper Vind
Kim Borch
Shamkant Anant Patkar
Christian Isak Joergensen
Robert Van Der Lans
Lise Munch Mikkelsen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Publication of MX337307B publication Critical patent/MX337307B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a una variante de una enzima lipolítica progenitora, caracterizada porque la variante tiene una secuencia de aminoácidos la cual, comparada con la enzima lipolítica progenitora consiste de la sustitución de los residuos aminoácidos que corresponden a D27R +T231R +N233R, +T231R +N233R +P256K,L227G +T231R +N233R, L227G +T231R +N233R +P256K, D27R +L227G +T231R O S216P +T231R +N233R de la SEQ ID NO: 2.
MX2013003000A 2008-02-29 2009-02-26 Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma. MX337307B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08152164 2008-02-29
US3309708P 2008-03-03 2008-03-03
PCT/EP2009/052247 WO2009106553A2 (en) 2008-02-29 2009-02-26 Lipolytic enzyme variant with improved stability and polynucleotides encoding same

Publications (1)

Publication Number Publication Date
MX337307B true MX337307B (es) 2016-02-25

Family

ID=39301592

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013003000A MX337307B (es) 2008-02-29 2009-02-26 Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma.
MX2010009077A MX2010009077A (es) 2008-02-29 2009-02-26 Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2010009077A MX2010009077A (es) 2008-02-29 2009-02-26 Variante de enzima lipolitica con estabilidad mejorada y polinucleotidos que codifican para la misma.

Country Status (8)

Country Link
US (1) US9163203B2 (es)
EP (1) EP2250258B1 (es)
JP (1) JP2011514805A (es)
CN (1) CN101990573B (es)
AR (1) AR070491A1 (es)
CA (1) CA2715521A1 (es)
MX (2) MX337307B (es)
WO (1) WO2009106553A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103052704A (zh) 2010-07-22 2013-04-17 荷兰联合利华有限公司 用于提高清洁的鼠李糖脂和酶的组合物
US9809787B2 (en) * 2011-12-29 2017-11-07 Novozymes A/S Detergent compositions comprising lipase
CN110093330B (zh) * 2012-10-12 2023-11-28 丹尼斯科美国公司 包含脂解酶变体的组合物和方法
WO2014074352A1 (en) * 2012-11-06 2014-05-15 The Regents Of The University Of California Dieselzymes and methanol tolerant lipases
MY192746A (en) 2013-05-14 2022-09-06 Novozymes As Detergent compositions
WO2015181119A2 (en) 2014-05-27 2015-12-03 Novozymes A/S Lipase variants and polynucleotides encoding same
US20170121644A1 (en) * 2014-07-08 2017-05-04 Novozymes A/S Organic Film Removal From Plastic Objects
WO2016091870A1 (en) * 2014-12-09 2016-06-16 Novozymes A/S Lipase variants and polynucleotides encoding same
ES2797725T3 (es) * 2014-12-22 2020-12-03 Novozymes As Composiciones detergentes, variantes de lipasa y polinucleótidos que codifican las mismas
EP3320089B1 (en) * 2015-07-06 2021-06-16 Novozymes A/S Lipase variants and polynucleotides encoding same
US20250311734A1 (en) 2022-05-14 2025-10-09 Novozymes A/S Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections
CN115927250A (zh) * 2022-08-26 2023-04-07 云南师范大学 第256位点突变的疏棉状嗜热丝孢菌脂肪酶突变体及其应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0258068B1 (en) 1986-08-29 1994-08-31 Novo Nordisk A/S Enzymatic detergent additive
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
US5176796A (en) 1988-12-13 1993-01-05 Jujo Paper Co., Ltd. Avoiding pitch troubles using acylgerol lipase
US5892013A (en) * 1990-09-13 1999-04-06 Novo Nordisk A/S Lipase variants
DK0548228T3 (da) * 1990-09-13 1999-05-10 Novo Nordisk As Lipasevarianter
JPH04240286A (ja) 1991-01-25 1992-08-27 Novo Nordisk As 耐熱性リパーゼによるピッチトラブル防止法
JPH06507071A (ja) 1991-05-01 1994-08-11 ノボザイムス アクティーゼルスカブ 安定化酵素
JP4068142B2 (ja) 1995-08-11 2008-03-26 ノボザイムス アクティーゼルスカブ 新規の脂肪分解酵素
KR20010108379A (ko) 1999-03-31 2001-12-07 피아 스타르 리파제 변이체
CA2431972C (en) * 2001-01-10 2012-10-23 Novozymes A/S Thermostable lipolytic enzyme variant
JP4287149B2 (ja) * 2001-02-07 2009-07-01 ノボザイムス アクティーゼルスカブ リパーゼ変異体
EP1851311A2 (en) * 2005-02-10 2007-11-07 Novozymes A/S Enzymatic enantioselective ester or amide hydrolysis or synthesis
ES2629332T3 (es) * 2006-01-23 2017-08-08 Novozymes A/S Variantes de lipasa
JP2009523900A (ja) * 2006-01-23 2009-06-25 ザ プロクター アンド ギャンブル カンパニー リパーゼと漂白剤触媒を含む組成物
JP2009523425A (ja) * 2006-01-23 2009-06-25 ザ プロクター アンド ギャンブル カンパニー 洗剤組成物
EP1976967A2 (en) * 2006-01-23 2008-10-08 The Procter and Gamble Company Detergent compositions
ES2601327T3 (es) * 2006-01-23 2017-02-14 Novozymes A/S Polipéptidos con actividad de lipasa y polinucleótidos que codifican los mismos
US8273348B2 (en) 2006-12-21 2012-09-25 Novozymes A/S Lipase variants for pharmaceutical use
EP2250259B1 (en) * 2008-02-29 2016-08-31 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same

Also Published As

Publication number Publication date
US20090221034A1 (en) 2009-09-03
CN101990573B (zh) 2014-01-22
CN101990573A (zh) 2011-03-23
WO2009106553A3 (en) 2009-12-10
US9163203B2 (en) 2015-10-20
MX2010009077A (es) 2010-09-24
EP2250258A2 (en) 2010-11-17
AR070491A1 (es) 2010-04-07
JP2011514805A (ja) 2011-05-12
CA2715521A1 (en) 2009-09-03
EP2250258B1 (en) 2017-01-04
WO2009106553A2 (en) 2009-09-03

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