MX336727B - Moleculas conjugadas nuevas que comprendenun peptido derivado del receptor cd4 acoplado a un polipeptido polianionico para el tratamiento de sida. - Google Patents
Moleculas conjugadas nuevas que comprendenun peptido derivado del receptor cd4 acoplado a un polipeptido polianionico para el tratamiento de sida.Info
- Publication number
- MX336727B MX336727B MX2013010688A MX2013010688A MX336727B MX 336727 B MX336727 B MX 336727B MX 2013010688 A MX2013010688 A MX 2013010688A MX 2013010688 A MX2013010688 A MX 2013010688A MX 336727 B MX336727 B MX 336727B
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- aids
- peptide derived
- receptor coupled
- conjugated molecules
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 108010041397 CD4 Antigens Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11305309A EP2505210A1 (en) | 2011-03-18 | 2011-03-18 | Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanionic polypeptide for the treatment of aids |
| US201261590992P | 2012-01-26 | 2012-01-26 | |
| PCT/EP2012/054674 WO2012126833A1 (en) | 2011-03-18 | 2012-03-16 | New conjugated molecules comprising a peptide derived from the cd4 receptor coupled to a polyanionic polypeptide for the treatment of aids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013010688A MX2013010688A (es) | 2014-03-27 |
| MX336727B true MX336727B (es) | 2016-01-27 |
Family
ID=44118425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013010688A MX336727B (es) | 2011-03-18 | 2012-03-16 | Moleculas conjugadas nuevas que comprendenun peptido derivado del receptor cd4 acoplado a un polipeptido polianionico para el tratamiento de sida. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9078928B2 (enExample) |
| EP (2) | EP2505210A1 (enExample) |
| JP (1) | JP6046060B2 (enExample) |
| CN (1) | CN103429269B (enExample) |
| BR (1) | BR112013023859A2 (enExample) |
| CA (1) | CA2830012C (enExample) |
| MX (1) | MX336727B (enExample) |
| WO (1) | WO2012126833A1 (enExample) |
| ZA (1) | ZA201306956B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3220957B1 (en) | 2014-10-24 | 2018-11-07 | Institut Pasteur | Conjugated molecules comprising a peptide derived from the cd4 receptor coupled to an anionic polypeptide for the treatment of aids |
| WO2017184564A1 (en) | 2016-04-18 | 2017-10-26 | Icagen, Inc. | Sensors and sensor arrays for detection of analytes |
| WO2018140590A1 (en) * | 2017-01-25 | 2018-08-02 | Massachusetts Institute Of Technology | Seft-labeling miniproteins and conjugates comprising them |
| CN109081789B (zh) * | 2017-06-13 | 2021-01-01 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰脂肪氨基酸，其合成，活性和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002338600A (ja) * | 2001-05-17 | 2002-11-27 | Japan Science & Technology Corp | Ｈｉｖ−１の感染を抑制するポリペプチド |
| RU2270690C1 (ru) * | 2004-06-11 | 2006-02-27 | Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") | Комплексное анти-вич соединение |
| FR2904627B1 (fr) | 2006-08-04 | 2008-11-07 | Pasteur Institut | Nouveaux peptides actives, purifies et isoles, derives du recepteur cd4 (mini-cd4) et leur procece de preparation |
| EP2087911A1 (en) | 2008-02-06 | 2009-08-12 | Institut Pasteur | Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanion for the treatment of AIDS |
-
2011
- 2011-03-18 EP EP11305309A patent/EP2505210A1/en not_active Withdrawn
-
2012
- 2012-03-16 US US14/005,688 patent/US9078928B2/en not_active Expired - Fee Related
- 2012-03-16 CA CA2830012A patent/CA2830012C/en not_active Expired - Fee Related
- 2012-03-16 CN CN201280013736.1A patent/CN103429269B/zh not_active Expired - Fee Related
- 2012-03-16 JP JP2013558459A patent/JP6046060B2/ja not_active Expired - Fee Related
- 2012-03-16 EP EP12710480.0A patent/EP2686019B1/en not_active Not-in-force
- 2012-03-16 BR BR112013023859A patent/BR112013023859A2/pt not_active IP Right Cessation
- 2012-03-16 MX MX2013010688A patent/MX336727B/es unknown
- 2012-03-16 WO PCT/EP2012/054674 patent/WO2012126833A1/en not_active Ceased
-
2013
- 2013-09-16 ZA ZA2013/06956A patent/ZA201306956B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2505210A1 (en) | 2012-10-03 |
| CA2830012C (en) | 2018-11-06 |
| ZA201306956B (en) | 2014-05-28 |
| CA2830012A1 (en) | 2012-09-27 |
| US9078928B2 (en) | 2015-07-14 |
| MX2013010688A (es) | 2014-03-27 |
| CN103429269B (zh) | 2016-05-11 |
| EP2686019B1 (en) | 2017-03-01 |
| EP2686019A1 (en) | 2014-01-22 |
| JP2014509604A (ja) | 2014-04-21 |
| WO2012126833A1 (en) | 2012-09-27 |
| JP6046060B2 (ja) | 2016-12-14 |
| BR112013023859A2 (pt) | 2018-09-25 |
| US20140107043A1 (en) | 2014-04-17 |
| CN103429269A (zh) | 2013-12-04 |
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