BR112013023859A2 - moléculas conjugadas compreendendo um peptídeo derivado do receptor cd4 acoplado a um polipeptídeo polianiônico para o tratamento da aids - Google Patents
moléculas conjugadas compreendendo um peptídeo derivado do receptor cd4 acoplado a um polipeptídeo polianiônico para o tratamento da aidsInfo
- Publication number
- BR112013023859A2 BR112013023859A2 BR112013023859A BR112013023859A BR112013023859A2 BR 112013023859 A2 BR112013023859 A2 BR 112013023859A2 BR 112013023859 A BR112013023859 A BR 112013023859A BR 112013023859 A BR112013023859 A BR 112013023859A BR 112013023859 A2 BR112013023859 A2 BR 112013023859A2
- Authority
- BR
- Brazil
- Prior art keywords
- aids
- treatment
- derived peptide
- conjugated molecules
- peptide coupled
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 208000030507 AIDS Diseases 0.000 title 1
- 108010041397 CD4 Antigens Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11305309A EP2505210A1 (en) | 2011-03-18 | 2011-03-18 | Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanionic polypeptide for the treatment of aids |
| US201261590992P | 2012-01-26 | 2012-01-26 | |
| PCT/EP2012/054674 WO2012126833A1 (en) | 2011-03-18 | 2012-03-16 | New conjugated molecules comprising a peptide derived from the cd4 receptor coupled to a polyanionic polypeptide for the treatment of aids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013023859A2 true BR112013023859A2 (pt) | 2018-09-25 |
Family
ID=44118425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013023859A BR112013023859A2 (pt) | 2011-03-18 | 2012-03-16 | moléculas conjugadas compreendendo um peptídeo derivado do receptor cd4 acoplado a um polipeptídeo polianiônico para o tratamento da aids |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9078928B2 (enExample) |
| EP (2) | EP2505210A1 (enExample) |
| JP (1) | JP6046060B2 (enExample) |
| CN (1) | CN103429269B (enExample) |
| BR (1) | BR112013023859A2 (enExample) |
| CA (1) | CA2830012C (enExample) |
| MX (1) | MX336727B (enExample) |
| WO (1) | WO2012126833A1 (enExample) |
| ZA (1) | ZA201306956B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3220957B1 (en) | 2014-10-24 | 2018-11-07 | Institut Pasteur | Conjugated molecules comprising a peptide derived from the cd4 receptor coupled to an anionic polypeptide for the treatment of aids |
| WO2017184564A1 (en) | 2016-04-18 | 2017-10-26 | Icagen, Inc. | Sensors and sensor arrays for detection of analytes |
| US11014961B2 (en) | 2017-01-25 | 2021-05-25 | Massachusetts Institute Of Technology | Self-labeling miniproteins and conjugates comprising them |
| CN109081789B (zh) * | 2017-06-13 | 2021-01-01 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰脂肪氨基酸，其合成，活性和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002338600A (ja) * | 2001-05-17 | 2002-11-27 | Japan Science & Technology Corp | Ｈｉｖ−１の感染を抑制するポリペプチド |
| RU2270690C1 (ru) * | 2004-06-11 | 2006-02-27 | Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") | Комплексное анти-вич соединение |
| FR2904627B1 (fr) * | 2006-08-04 | 2008-11-07 | Pasteur Institut | Nouveaux peptides actives, purifies et isoles, derives du recepteur cd4 (mini-cd4) et leur procece de preparation |
| EP2087911A1 (en) * | 2008-02-06 | 2009-08-12 | Institut Pasteur | Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanion for the treatment of AIDS |
-
2011
- 2011-03-18 EP EP11305309A patent/EP2505210A1/en not_active Withdrawn
-
2012
- 2012-03-16 WO PCT/EP2012/054674 patent/WO2012126833A1/en not_active Ceased
- 2012-03-16 US US14/005,688 patent/US9078928B2/en not_active Expired - Fee Related
- 2012-03-16 CA CA2830012A patent/CA2830012C/en not_active Expired - Fee Related
- 2012-03-16 CN CN201280013736.1A patent/CN103429269B/zh not_active Expired - Fee Related
- 2012-03-16 MX MX2013010688A patent/MX336727B/es unknown
- 2012-03-16 BR BR112013023859A patent/BR112013023859A2/pt not_active IP Right Cessation
- 2012-03-16 EP EP12710480.0A patent/EP2686019B1/en not_active Not-in-force
- 2012-03-16 JP JP2013558459A patent/JP6046060B2/ja not_active Expired - Fee Related
-
2013
- 2013-09-16 ZA ZA2013/06956A patent/ZA201306956B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6046060B2 (ja) | 2016-12-14 |
| CN103429269A (zh) | 2013-12-04 |
| MX2013010688A (es) | 2014-03-27 |
| US20140107043A1 (en) | 2014-04-17 |
| EP2686019A1 (en) | 2014-01-22 |
| CA2830012C (en) | 2018-11-06 |
| US9078928B2 (en) | 2015-07-14 |
| MX336727B (es) | 2016-01-27 |
| JP2014509604A (ja) | 2014-04-21 |
| CA2830012A1 (en) | 2012-09-27 |
| EP2505210A1 (en) | 2012-10-03 |
| CN103429269B (zh) | 2016-05-11 |
| ZA201306956B (en) | 2014-05-28 |
| WO2012126833A1 (en) | 2012-09-27 |
| EP2686019B1 (en) | 2017-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2662 DE 11-01-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |