MX3313E - Procedimiento para preparar acetamidoximas substituidas - Google Patents
Procedimiento para preparar acetamidoximas substituidasInfo
- Publication number
- MX3313E MX3313E MX000099U MX9976U MX3313E MX 3313 E MX3313 E MX 3313E MX 000099 U MX000099 U MX 000099U MX 9976 U MX9976 U MX 9976U MX 3313 E MX3313 E MX 3313E
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- group
- carbon atoms
- see
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a procedimiento para preparar acetamidoximas substituídas, de fórmula (VER FIGURA) en la cual R representa un átomo de hidrógeno, un átomo de cloro, un grupo alquilo que comprende de 1 a 4 átomos de carbono, o un grupo alcoxi que comprende de 1 a 3 átomos de carbono y R1 representa: un átomo de hidrógeno; un grupo benzoilo de la fórmula: (VER FIGURA) en donde R2 designa un átomo de hidrógeno, un átomo de cloro, un grupo nitro, un grupo alcoxi que comprende de 1 a 3 átomos de carbono o un grupo trifluorometilo; un grupo carbamoilo de fórmula -CO-NH-R3 en donde R3 representa un grupo alquilo que comprende de 1 a 4 átomos de carbono, un grupo cicloalquilo que comprende cuando mucho 6 átomos de carbono o un núcleo fenilo, caracterizado en que consiste en hacer reaccionar un ciano-2-acetanilida de fórmula (II): (VER FIGURA) en la cual R tiene el mismo significado que en la fórmula (I) con hidroxilamina a reflujo en un disolvente orgánico tal como metanol; y el producto obtenido eventualmente se hace reaccionar con un isocianato de fórmula (IV): en la cual R3 tiene el mismo significado que en la fórmula (I), reacción que se efectúa en un disolvente orgánico tal como cloroformo, en principio a la temperatura ambiente hasta reflujo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7509263A FR2305174A1 (fr) | 1975-03-25 | 1975-03-25 | Nouveaux acetamidoximes, leur procede de preparation et leur application en therapeutique |
FR7605098A FR2342063A2 (fr) | 1976-02-24 | 1976-02-24 | Nouveaux acetamidoximes, leur procede de preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
MX3313E true MX3313E (es) | 1980-09-17 |
Family
ID=26218795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX000099U MX3313E (es) | 1975-03-25 | 1976-03-19 | Procedimiento para preparar acetamidoximas substituidas |
Country Status (14)
Country | Link |
---|---|
US (1) | US4041072A (es) |
JP (1) | JPS51125330A (es) |
AU (1) | AU503245B2 (es) |
CA (1) | CA1056845A (es) |
CH (2) | CH615663A5 (es) |
DE (1) | DE2609764A1 (es) |
ES (1) | ES446329A1 (es) |
GB (1) | GB1488462A (es) |
IT (1) | IT1062826B (es) |
LU (1) | LU74487A1 (es) |
MX (1) | MX3313E (es) |
NL (1) | NL7603101A (es) |
SE (1) | SE7603517L (es) |
SU (1) | SU588915A3 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4169106A (en) * | 1977-09-30 | 1979-09-25 | Cooper Laboratories, Inc. | Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines |
DE2965415D1 (en) * | 1978-11-03 | 1983-06-16 | Bayer Ag | Anilinomethyloxime ethers and processes for their production |
US9527805B2 (en) * | 2010-09-10 | 2016-12-27 | Robert A. Casero | Small molecules as epigenetic modulators of lysine-specific demethylase 1 and methods of treating disorders |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1434131A (fr) * | 1964-07-31 | 1966-04-08 | Usines Rhone Poulenc Soc D | Nouveaux dérivés de l'acétamidine |
US3624151A (en) * | 1967-10-16 | 1971-11-30 | Stauffer Chemical Co | Glyoxylanilideoximino carbamates |
US3560555A (en) * | 1968-12-27 | 1971-02-02 | Du Pont | Preparation of 1-(carbamoyl)-n-(carbamoyloxy) thioformimidates from alkyl acetoacetates |
BE759128R (fr) * | 1969-11-18 | 1971-05-18 | Usv Pharma Corp | Carbamoyl oximes et leur methode de |
US3819700A (en) * | 1970-04-23 | 1974-06-25 | R Bellina | 2-(hydrocarbylthio)-2-(hydroxyimino)-acetamide s-oxides and derivatives |
US3766270A (en) * | 1971-06-09 | 1973-10-16 | Basf Ag | Alkylaminooxanil oximes |
US3867447A (en) * | 1972-08-25 | 1975-02-18 | Du Pont | Hydroxyguanidine O-carbamates |
US4000196A (en) | 1973-06-25 | 1976-12-28 | E. I. Du Pont De Nemours And Company | 1,1,3-trisubstituted hydroxyguanidines |
US3872169A (en) * | 1974-02-14 | 1975-03-18 | Du Pont | Amino-oxime acetamide-0-carbamates as antihypertensives |
-
1976
- 1976-03-02 GB GB8240/76A patent/GB1488462A/en not_active Expired
- 1976-03-05 LU LU74487A patent/LU74487A1/xx unknown
- 1976-03-09 DE DE19762609764 patent/DE2609764A1/de not_active Withdrawn
- 1976-03-11 AU AU11882/76A patent/AU503245B2/en not_active Expired
- 1976-03-16 CA CA248,360A patent/CA1056845A/en not_active Expired
- 1976-03-18 US US05/668,061 patent/US4041072A/en not_active Expired - Lifetime
- 1976-03-19 MX MX000099U patent/MX3313E/es unknown
- 1976-03-22 JP JP51031171A patent/JPS51125330A/ja active Pending
- 1976-03-22 SE SE7603517A patent/SE7603517L/xx unknown
- 1976-03-24 IT IT67690/76A patent/IT1062826B/it active
- 1976-03-24 NL NL7603101A patent/NL7603101A/xx not_active Application Discontinuation
- 1976-03-24 ES ES446329A patent/ES446329A1/es not_active Expired
- 1976-03-25 SU SU762334055A patent/SU588915A3/ru active
-
1978
- 1978-09-01 CH CH922178A patent/CH615663A5/fr not_active IP Right Cessation
- 1978-09-01 CH CH922278A patent/CH615415A5/fr not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPS51125330A (en) | 1976-11-01 |
GB1488462A (en) | 1977-10-12 |
DE2609764A1 (de) | 1976-10-07 |
AU503245B2 (en) | 1979-08-30 |
LU74487A1 (es) | 1977-01-10 |
AU1188276A (en) | 1977-09-15 |
US4041072A (en) | 1977-08-09 |
CH615415A5 (es) | 1980-01-31 |
IT1062826B (it) | 1985-02-11 |
CH615663A5 (es) | 1980-02-15 |
SU588915A3 (ru) | 1978-01-15 |
SE7603517L (sv) | 1976-09-26 |
NL7603101A (nl) | 1976-09-28 |
CA1056845A (en) | 1979-06-19 |
ES446329A1 (es) | 1977-06-16 |
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