MX3121E - Metodo para formar peliculas multimoleculares que contienen proteinas inmunologicamente coordinadas - Google Patents

Metodo para formar peliculas multimoleculares que contienen proteinas inmunologicamente coordinadas

Info

Publication number
MX3121E
MX3121E MX100002U MX10000274U MX3121E MX 3121 E MX3121 E MX 3121E MX 100002 U MX100002 U MX 100002U MX 10000274 U MX10000274 U MX 10000274U MX 3121 E MX3121 E MX 3121E
Authority
MX
Mexico
Prior art keywords
protein
molecules
inert
coordinated
proteins
Prior art date
Application number
MX100002U
Other languages
English (en)
Inventor
Ivar Giaever
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Electric filed Critical Gen Electric
Publication of MX3121E publication Critical patent/MX3121E/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a un método para formar películas multimoleculares que contienen proteínas inmunológicamente coordinadas, caracterizado porque comprende los pasos de revestir un substrato con una capa monomolecular de proteína, que consiste de una primera proteína inmunológicamente reactiva y una proteína inerte, de manera que las moléculas de la primera proteína queden separadas entre sí por las moléculas de la proteína inerte; y exponer subsecuentemente el substrato revestido a una solución de una segunda proteína inmonulógicamente reactiva, específica para la primera proteína para causar una reacción inmunológica con la misma, mediante la cual las moléculas de la segunda proteína se ligan con las moléculas de la primera proteína para formar una capa bimolecular sobre el substrato, y la proteína inerte está en una cantidad suficiente para obtener suficiente separación promedio entre las moléculas de la primera proteína adyacentes en la capa molecular, de manera que las moleculas de la segunda proteína retienen un mayor número de sitios activos para una reacción inmunológica adicional, que si la capa monomolecular de proteína no contuviera proteína inerte.
MX100002U 1973-08-30 1974-08-29 Metodo para formar peliculas multimoleculares que contienen proteinas inmunologicamente coordinadas MX3121E (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39295173A 1973-08-30 1973-08-30
US39295073A 1973-08-30 1973-08-30

Publications (1)

Publication Number Publication Date
MX3121E true MX3121E (es) 1980-04-21

Family

ID=27014084

Family Applications (1)

Application Number Title Priority Date Filing Date
MX100002U MX3121E (es) 1973-08-30 1974-08-29 Metodo para formar peliculas multimoleculares que contienen proteinas inmunologicamente coordinadas

Country Status (12)

Country Link
JP (1) JPS5916669B2 (es)
AT (1) AT347598B (es)
BR (1) BR7407193D0 (es)
CH (1) CH617012A5 (es)
DE (1) DE2440367C2 (es)
DK (1) DK151240C (es)
FR (1) FR2257259B1 (es)
GB (1) GB1486826A (es)
IT (1) IT1020283B (es)
MX (1) MX3121E (es)
NL (1) NL177628C (es)
SE (1) SE457118B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2638207C2 (de) * 1975-08-27 1985-10-03 General Electric Co., Schenectady, N.Y. Verfahren zum Bilden multimolekularer immunologisch komplexierter Filme
DE2729555C2 (de) * 1976-07-06 1985-12-12 Becton, Dickinson and Co., East Rutherford, N.J. Verfahren zur Bildung eines Überzugs eines Rezeptors auf ein Kunststoffsubstrat, das dabei erhaltende Produkt und seine Verwendung
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4189464A (en) * 1978-05-05 1980-02-19 Institute For Cancer Research Hepatitis B testing reagent and method
AR231590A1 (es) * 1981-04-29 1984-12-28 Ciba Geigy Ag Dispositivo de analisis inmunologico y procedimiento para obtenerlo
SE8200442L (sv) * 1982-01-27 1983-07-28 Forsvarets Forsknings Forfarande vid detektion av organiska molekyler, sasom biomolekyler
EP0112721B1 (en) * 1982-12-21 1988-05-18 Ares-Serono N.V. Assay technique
US4822566A (en) * 1985-11-19 1989-04-18 The Johns Hopkins University Optimized capacitive sensor for chemical analysis and measurement
US5114674A (en) * 1987-05-01 1992-05-19 Biotronic Systems Corporation Added array of molecular chains for interfering with electrical fields
CN112924666A (zh) * 2019-12-05 2021-06-08 菲鹏生物股份有限公司 固体支持物包被产物及其制备方法、应用和产品

Also Published As

Publication number Publication date
AU7251474A (en) 1976-02-26
NL7411596A (nl) 1975-03-04
FR2257259B1 (es) 1982-07-02
DE2440367C2 (de) 1984-03-15
JPS5916669B2 (ja) 1984-04-17
NL177628B (nl) 1985-05-17
DK151240B (da) 1987-11-16
NL177628C (nl) 1985-10-16
JPS5070517A (es) 1975-06-12
SE7410971L (es) 1975-03-03
IT1020283B (it) 1977-12-20
AT347598B (de) 1979-01-10
ATA704774A (de) 1978-05-15
GB1486826A (en) 1977-09-28
FR2257259A1 (es) 1975-08-08
DE2440367A1 (de) 1975-03-06
BR7407193D0 (pt) 1975-06-24
DK457174A (es) 1975-04-28
CH617012A5 (en) 1980-04-30
SE457118B (sv) 1988-11-28
DK151240C (da) 1988-04-18

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