MX2024000653A - Un proceso para la sintesis de ester de butilo de acido 4-((r)-2-{[6-((s)-3-metoxi-pirrolidin-1-il)-2-fenil-pirimidin-4-c arbonil]-amino}-3-fosfono-propionil)-piperazin-1-carboxilico. - Google Patents

Un proceso para la sintesis de ester de butilo de acido 4-((r)-2-{[6-((s)-3-metoxi-pirrolidin-1-il)-2-fenil-pirimidin-4-c arbonil]-amino}-3-fosfono-propionil)-piperazin-1-carboxilico.

Info

Publication number
MX2024000653A
MX2024000653A MX2024000653A MX2024000653A MX2024000653A MX 2024000653 A MX2024000653 A MX 2024000653A MX 2024000653 A MX2024000653 A MX 2024000653A MX 2024000653 A MX2024000653 A MX 2024000653A MX 2024000653 A MX2024000653 A MX 2024000653A
Authority
MX
Mexico
Prior art keywords
phosphono
piperazine
carbonyl
methoxy
phenyl
Prior art date
Application number
MX2024000653A
Other languages
English (en)
Spanish (es)
Inventor
Stefan Reber
Nicole Blumer
Romain Claveau
Fabian Feyen
Leanne Hall
Stephen Hughes
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of MX2024000653A publication Critical patent/MX2024000653A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2024000653A 2021-07-13 2022-07-11 Un proceso para la sintesis de ester de butilo de acido 4-((r)-2-{[6-((s)-3-metoxi-pirrolidin-1-il)-2-fenil-pirimidin-4-c arbonil]-amino}-3-fosfono-propionil)-piperazin-1-carboxilico. MX2024000653A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2021069486 2021-07-13
PCT/EP2022/069238 WO2023285342A2 (en) 2021-07-13 2022-07-11 A process for the synthesis of 4-((r)-2-{[6-((s)-3-methoxy-pyrrolidin-1-yl)-2-phenyl- pyrimidine-4-carbonyl]-amino}-3-phosphono-propionyl)-piperazine-1 -carboxylic acid butyl ester

Publications (1)

Publication Number Publication Date
MX2024000653A true MX2024000653A (es) 2024-01-31

Family

ID=82748669

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024000653A MX2024000653A (es) 2021-07-13 2022-07-11 Un proceso para la sintesis de ester de butilo de acido 4-((r)-2-{[6-((s)-3-metoxi-pirrolidin-1-il)-2-fenil-pirimidin-4-c arbonil]-amino}-3-fosfono-propionil)-piperazin-1-carboxilico.

Country Status (10)

Country Link
US (1) US20240317784A1 (https=)
EP (1) EP4370525A2 (https=)
JP (1) JP2024524658A (https=)
KR (1) KR20240033005A (https=)
CN (1) CN117616033A (https=)
CA (1) CA3223733A1 (https=)
IL (1) IL309948A (https=)
MX (1) MX2024000653A (https=)
TW (1) TW202317140A (https=)
WO (1) WO2023285342A2 (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2225253B1 (en) * 2007-11-29 2012-06-27 Actelion Pharmaceuticals Ltd. Phosphonic acid derivates and their use as p2y12 receptor antagonists
EP3515924B1 (en) * 2016-09-22 2021-12-15 Idorsia Pharmaceuticals Ltd Crystalline forms
MA49887A (fr) 2017-03-15 2020-06-24 Idorsia Pharmaceuticals Ltd Administration sous-cutanée d'un antagoniste du récepteur p2y12

Also Published As

Publication number Publication date
JP2024524658A (ja) 2024-07-05
KR20240033005A (ko) 2024-03-12
IL309948A (en) 2024-03-01
WO2023285342A3 (en) 2023-04-13
WO2023285342A2 (en) 2023-01-19
TW202317140A (zh) 2023-05-01
CN117616033A (zh) 2024-02-27
CA3223733A1 (en) 2023-01-19
EP4370525A2 (en) 2024-05-22
US20240317784A1 (en) 2024-09-26

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