MX2024000116A - Agentes farmacologicos para prevenir y tratar cataratas y enfermedades oculares de presbicia. - Google Patents

Agentes farmacologicos para prevenir y tratar cataratas y enfermedades oculares de presbicia.

Info

Publication number
MX2024000116A
MX2024000116A MX2024000116A MX2024000116A MX2024000116A MX 2024000116 A MX2024000116 A MX 2024000116A MX 2024000116 A MX2024000116 A MX 2024000116A MX 2024000116 A MX2024000116 A MX 2024000116A MX 2024000116 A MX2024000116 A MX 2024000116A
Authority
MX
Mexico
Prior art keywords
prevent
eye diseases
pharmacological agents
subject
cataracts
Prior art date
Application number
MX2024000116A
Other languages
English (en)
Spanish (es)
Inventor
Santosh C Sinha
Sridhar Govinda Prasad
Original Assignee
Plex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plex Pharmaceuticals Inc filed Critical Plex Pharmaceuticals Inc
Publication of MX2024000116A publication Critical patent/MX2024000116A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/12Esters of phosphoric acids with hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2024000116A 2021-06-28 2022-06-28 Agentes farmacologicos para prevenir y tratar cataratas y enfermedades oculares de presbicia. MX2024000116A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163215818P 2021-06-28 2021-06-28
PCT/US2022/035336 WO2023278464A1 (en) 2021-06-28 2022-06-28 Pharmacological agents for preventing and treating cataracts and presbyopia eye diseases

Publications (1)

Publication Number Publication Date
MX2024000116A true MX2024000116A (es) 2024-06-19

Family

ID=84692077

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024000116A MX2024000116A (es) 2021-06-28 2022-06-28 Agentes farmacologicos para prevenir y tratar cataratas y enfermedades oculares de presbicia.

Country Status (7)

Country Link
US (1) US20240327439A1 (https=)
EP (1) EP4362923A4 (https=)
JP (1) JP2024524433A (https=)
CN (2) CN116963727A (https=)
CA (1) CA3225704A1 (https=)
MX (1) MX2024000116A (https=)
WO (1) WO2023278464A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11872236B2 (en) 2018-04-05 2024-01-16 Calasia Pharmaceuticals, Inc. Pharmacological agents for treating ocular diseases
EP4243798A4 (en) * 2020-11-13 2024-08-21 Plex Pharmaceuticals, Inc. PHARMACOLOGICAL AGENTS FOR TREATING OCULAR PATHOLOGIES

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID19540A (id) * 1997-01-22 1998-07-23 Hoffmann La Roche Metode pembuatan turunan-turunan benzofenon
US20010044584A1 (en) * 1997-08-28 2001-11-22 Kensey Kenneth R. In vivo delivery methods and compositions
KR20060013632A (ko) * 2002-05-17 2006-02-13 오쎄라 파마슈티걸즈, 인크. 백내장 및 다른 안질환 발병의 개선
WO2014164667A1 (en) * 2013-03-11 2014-10-09 Georgetown University Dengue and west nile virus protease inhibitors
WO2018036498A1 (en) * 2016-08-24 2018-03-01 National Institute Of Biological Sciences, Beijing Entacapone-related compounds to treat macular degeneration
US11872236B2 (en) * 2018-04-05 2024-01-16 Calasia Pharmaceuticals, Inc. Pharmacological agents for treating ocular diseases
KR20230021002A (ko) * 2020-06-09 2023-02-13 에이에스엠엘 홀딩 엔.브이. 내장 동축 조명부를 갖는 리소그래피 사전-정렬 이미징 센서
EP4243798A4 (en) * 2020-11-13 2024-08-21 Plex Pharmaceuticals, Inc. PHARMACOLOGICAL AGENTS FOR TREATING OCULAR PATHOLOGIES

Also Published As

Publication number Publication date
WO2023278464A1 (en) 2023-01-05
US20240327439A1 (en) 2024-10-03
CN116963727A (zh) 2023-10-27
CA3225704A1 (en) 2023-01-05
JP2024524433A (ja) 2024-07-05
EP4362923A4 (en) 2025-03-19
EP4362923A1 (en) 2024-05-08
CN117915900A (zh) 2024-04-19

Similar Documents

Publication Publication Date Title
MX2024000116A (es) Agentes farmacologicos para prevenir y tratar cataratas y enfermedades oculares de presbicia.
CL2021001288A1 (es) Heterociclos funcionalizados como agentes antivirales
PE20250114A1 (es) Compuestos indol sustituidos y metodos de uso de los mismos
CL2020002157A1 (es) Derivados de triazina para el tratamiento de enfermedades relacionadas con neurotrofinas.
CL2020002075A1 (es) Métodos para tratar el cáncer con anticuerpos anti-pd1.
CO5580771A2 (es) Antagonistas ccr5 como agentes terapeuticos
UY28135A1 (es) Derivados de pirimidina para el tratamiento de crecimiento celular anormal
AR043700A1 (es) Derivados de 3-substituida-4-pirimidona
SV2009002925A (es) Derivados de oxadiazol
AR033147A1 (es) Compuestos de amida.
CL2024003258A1 (es) Inhibidores de amida heterocíclica bicíclica de sodio activado por voltaje 1.8 (nav1.8) para tratar dolor
AR035651A1 (es) Uso de derivados de indol para la manufactura de un medicamento para reducir la presion intraocular y una composicion
PE20081781A1 (es) Agonistas de adrenoreceptores alfa2c funcionalmente selectivos
CO2024000054A2 (es) Forma cristalina de tolebrutinib y método de preparación y su uso
BR112022016131A2 (pt) Compostos para tratamento de infecção por coronavírus
PA8475401A1 (es) Compuestos de sulfonilbenceno como agentes antiinflamatorios/analgesicos
MX2022002839A (es) Nuevo compuesto heterocíclico aromático tricíclico, método de preparación del mismo, composición farmacéutica y aplicación del mismo.
AR014964A1 (es) Derivados de indol, composiciones farmaceuticas que los contienen, agentes para reducir la presion intraocular, tratar glaucoma e hipertension ocular, usosen la fabricacion de composiciones farmaceuticas y procedimiento de fabricacion de dichas composiciones
CL2025001155A1 (es) Compuestos 2,4,6-trisustituidos 1,3,5-triazinas moduladores de cx3cr1.
CO2022012884A2 (es) Compuestos de amino pirimidina fusionados
ES2177543T3 (es) Metodo para reducir la presion intraocular en el ojo de mamiferos por administracion de antagonistas muscarinicos.
EA200870090A1 (ru) Применение производных сульфамида, включающих гетероцикл, конденсированный с бензольным кольцом, для лечения депрессии
CO2025002028A2 (es) Derivados novedosos de indol sulfonamida 7 sustituidos
AR043253A1 (es) 4-[(2,4-dicloro-5-metoxifenil)amino] -6- alcoxi-3-quinolina carbonitrilos para el tratamiento de lesiones isquemicas
MX2021014682A (es) Agentes farmacológicos para tratar enfermedades de agregación de proteínas de los ojos.