MX2023011640A - Composiciones de vacuna de staphylococcus aureus. - Google Patents

Composiciones de vacuna de staphylococcus aureus.

Info

Publication number
MX2023011640A
MX2023011640A MX2023011640A MX2023011640A MX2023011640A MX 2023011640 A MX2023011640 A MX 2023011640A MX 2023011640 A MX2023011640 A MX 2023011640A MX 2023011640 A MX2023011640 A MX 2023011640A MX 2023011640 A MX2023011640 A MX 2023011640A
Authority
MX
Mexico
Prior art keywords
aureus
staphylococcus aureus
immunogenic compositions
vaccine compositions
aureus vaccine
Prior art date
Application number
MX2023011640A
Other languages
English (en)
Inventor
Victor J Torres
Jan Theunis Poolman
Jinquan Luo
Peter T Buckley
Jeroen Geurtsen
Sandeep Somani
Brian Morrow
Sergey Konstantinov
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of MX2023011640A publication Critical patent/MX2023011640A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente descripción se refiere a composiciones inmunogénicas para inducir una respuesta inmune en un sujeto para el tratamiento y/o la prevención de una infección de Staphylococcus aureus. Las composiciones inmunogénicas que se describen en el presente documento comprenden un polipéptido A (SpA) de la proteína A de S. aureus y una leucocidina A de S. aureus (LukA) y/o polipéptido variante de leucocidina B (LukB). La presente descripción se refiere además a métodos para generar una respuesta inmune contra S. aureus en un sujeto que implica administrar las composiciones inmunogénicas descritas.
MX2023011640A 2021-04-02 2022-03-31 Composiciones de vacuna de staphylococcus aureus. MX2023011640A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163170089P 2021-04-02 2021-04-02
US202163249452P 2021-09-28 2021-09-28
PCT/US2022/022773 WO2022212667A1 (en) 2021-04-02 2022-03-31 Staphylococcus aureus vaccine compositions

Publications (1)

Publication Number Publication Date
MX2023011640A true MX2023011640A (es) 2023-10-13

Family

ID=83456741

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023011640A MX2023011640A (es) 2021-04-02 2022-03-31 Composiciones de vacuna de staphylococcus aureus.

Country Status (11)

Country Link
EP (1) EP4313303A1 (es)
JP (1) JP2024512751A (es)
KR (1) KR20230165808A (es)
AU (1) AU2022246874A1 (es)
BR (1) BR112023019605A2 (es)
CA (1) CA3215751A1 (es)
IL (1) IL307178A (es)
MX (1) MX2023011640A (es)
TW (1) TW202241496A (es)
UY (1) UY39714A (es)
WO (1) WO2022212667A1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3121191B1 (en) * 2010-05-05 2018-09-26 New York University Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof
WO2018232014A1 (en) * 2017-06-13 2018-12-20 Integrated Biotherapeutics, Inc. Immunogenic compositions comprising staphylococcus aureus leukocidin luka and lukb derived polypeptides

Also Published As

Publication number Publication date
KR20230165808A (ko) 2023-12-05
TW202241496A (zh) 2022-11-01
JP2024512751A (ja) 2024-03-19
WO2022212667A1 (en) 2022-10-06
IL307178A (en) 2023-11-01
EP4313303A1 (en) 2024-02-07
BR112023019605A2 (pt) 2023-12-05
AU2022246874A9 (en) 2024-01-11
CA3215751A1 (en) 2022-10-06
AU2022246874A1 (en) 2023-09-21
UY39714A (es) 2022-10-31

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