BR112023019605A2 - Composições de vacina contra staphylococcus aureus - Google Patents
Composições de vacina contra staphylococcus aureusInfo
- Publication number
- BR112023019605A2 BR112023019605A2 BR112023019605A BR112023019605A BR112023019605A2 BR 112023019605 A2 BR112023019605 A2 BR 112023019605A2 BR 112023019605 A BR112023019605 A BR 112023019605A BR 112023019605 A BR112023019605 A BR 112023019605A BR 112023019605 A2 BR112023019605 A2 BR 112023019605A2
- Authority
- BR
- Brazil
- Prior art keywords
- staphylococcus aureus
- aureus
- vaccine compositions
- against staphylococcus
- immunogenic compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 241000191967 Staphylococcus aureus Species 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 abstract 3
- 108010014603 Leukocidins Proteins 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 206010041925 Staphylococcal infections Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 208000015339 staphylococcus aureus infection Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
composições de vacina contra staphylococcus aureus. a presente invenção refere-se a composições imunogênicas para induzir uma resposta imune em um indivíduo para o tratamento e/ou prevenção de uma infecção por staphylococcus aureus. as composições imunogênicas aqui divulgadas compreendem um polipeptídeo da proteína a de s. aureus (spa) e um polipeptídeo variante de leucocidina a de s. aureus (luka) e/ou leucocidina b (lukb). a presente invenção refere-se ainda a métodos para gerar uma resposta imune contra s. aureus em um indivíduo que envolve a administração das composições imunogênicas divulgadas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163170089P | 2021-04-02 | 2021-04-02 | |
| US202163249452P | 2021-09-28 | 2021-09-28 | |
| PCT/US2022/022773 WO2022212667A1 (en) | 2021-04-02 | 2022-03-31 | Staphylococcus aureus vaccine compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023019605A2 true BR112023019605A2 (pt) | 2023-12-05 |
Family
ID=83456741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023019605A BR112023019605A2 (pt) | 2021-04-02 | 2022-03-31 | Composições de vacina contra staphylococcus aureus |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP4313303A1 (pt) |
| JP (1) | JP2024512751A (pt) |
| KR (1) | KR20230165808A (pt) |
| AU (1) | AU2022246874A1 (pt) |
| BR (1) | BR112023019605A2 (pt) |
| CA (1) | CA3215751A1 (pt) |
| IL (1) | IL307178A (pt) |
| TW (1) | TW202241496A (pt) |
| UY (1) | UY39714A (pt) |
| WO (1) | WO2022212667A1 (pt) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3444268T (lt) * | 2010-05-05 | 2022-04-11 | New York University | Staphylococcus aureus leukocidinai, terapinės kompozicijos ir jų panaudojimo būdai |
| AU2018285857B2 (en) * | 2017-06-13 | 2022-10-06 | Abvacc, Inc. | Immunogenic compositions comprising Staphylococcus aureus leukocidin lukA and lukB derived polypeptides |
-
2022
- 2022-03-31 CA CA3215751A patent/CA3215751A1/en active Pending
- 2022-03-31 JP JP2023560756A patent/JP2024512751A/ja active Pending
- 2022-03-31 BR BR112023019605A patent/BR112023019605A2/pt unknown
- 2022-03-31 WO PCT/US2022/022773 patent/WO2022212667A1/en active Application Filing
- 2022-03-31 IL IL307178A patent/IL307178A/en unknown
- 2022-03-31 KR KR1020237037504A patent/KR20230165808A/ko unknown
- 2022-03-31 EP EP22782187.3A patent/EP4313303A1/en active Pending
- 2022-03-31 AU AU2022246874A patent/AU2022246874A1/en active Pending
- 2022-04-01 TW TW111112917A patent/TW202241496A/zh unknown
- 2022-04-01 UY UY0001039714A patent/UY39714A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4313303A1 (en) | 2024-02-07 |
| JP2024512751A (ja) | 2024-03-19 |
| TW202241496A (zh) | 2022-11-01 |
| AU2022246874A9 (en) | 2024-01-11 |
| AU2022246874A1 (en) | 2023-09-21 |
| UY39714A (es) | 2022-10-31 |
| CA3215751A1 (en) | 2022-10-06 |
| KR20230165808A (ko) | 2023-12-05 |
| IL307178A (en) | 2023-11-01 |
| WO2022212667A1 (en) | 2022-10-06 |
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