MX2023006681A - Calibracion de modelo de cromatografia de intercambio ionico mecanistico. - Google Patents

Calibracion de modelo de cromatografia de intercambio ionico mecanistico.

Info

Publication number
MX2023006681A
MX2023006681A MX2023006681A MX2023006681A MX2023006681A MX 2023006681 A MX2023006681 A MX 2023006681A MX 2023006681 A MX2023006681 A MX 2023006681A MX 2023006681 A MX2023006681 A MX 2023006681A MX 2023006681 A MX2023006681 A MX 2023006681A
Authority
MX
Mexico
Prior art keywords
dpfr
tracer molecule
transport model
mechanistic
ion
Prior art date
Application number
MX2023006681A
Other languages
English (en)
Spanish (es)
Inventor
Juliane Dorothea Glaser
Original Assignee
Amgen Res Munich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Res Munich Gmbh filed Critical Amgen Res Munich Gmbh
Publication of MX2023006681A publication Critical patent/MX2023006681A/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8693Models, e.g. prediction of retention times, method development and validation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44743Introducing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8624Detection of slopes or peaks; baseline correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8827Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/16Injection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Monitoring And Testing Of Nuclear Reactors (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
MX2023006681A 2020-12-09 2021-12-03 Calibracion de modelo de cromatografia de intercambio ionico mecanistico. MX2023006681A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063123170P 2020-12-09 2020-12-09
PCT/IB2021/061322 WO2022123412A1 (en) 2020-12-09 2021-12-03 Mechanistic ion-exchange chromatography model calibration

Publications (1)

Publication Number Publication Date
MX2023006681A true MX2023006681A (es) 2023-06-22

Family

ID=78845067

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023006681A MX2023006681A (es) 2020-12-09 2021-12-03 Calibracion de modelo de cromatografia de intercambio ionico mecanistico.

Country Status (7)

Country Link
US (1) US20250264445A1 (https=)
EP (1) EP4260060B1 (https=)
JP (1) JP7830467B2 (https=)
AU (1) AU2021397425A1 (https=)
CA (1) CA3198086A1 (https=)
MX (1) MX2023006681A (https=)
WO (1) WO2022123412A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230359888A1 (en) * 2022-05-03 2023-11-09 Accenture Global Solutions Limited Optimization and digital twin of chromatography purification process using physics-informed neural networks
CN121057616A (zh) * 2023-05-04 2025-12-02 环球生命科学解决方案德国有限公司 分离过程的跨规模工艺开发方法

Also Published As

Publication number Publication date
CA3198086A1 (en) 2022-06-16
WO2022123412A1 (en) 2022-06-16
JP7830467B2 (ja) 2026-03-16
EP4260060A1 (en) 2023-10-18
JP2024501406A (ja) 2024-01-12
AU2021397425A1 (en) 2023-05-25
AU2021397425A9 (en) 2024-10-24
US20250264445A1 (en) 2025-08-21
EP4260060B1 (en) 2026-04-08

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