AU2021397425A1 - Mechanistic ion-exchange chromatography model calibration - Google Patents
Mechanistic ion-exchange chromatography model calibration Download PDFInfo
- Publication number
- AU2021397425A1 AU2021397425A1 AU2021397425A AU2021397425A AU2021397425A1 AU 2021397425 A1 AU2021397425 A1 AU 2021397425A1 AU 2021397425 A AU2021397425 A AU 2021397425A AU 2021397425 A AU2021397425 A AU 2021397425A AU 2021397425 A1 AU2021397425 A1 AU 2021397425A1
- Authority
- AU
- Australia
- Prior art keywords
- dpfr
- model
- column
- transport
- parameters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8693—Models, e.g. prediction of retention times, method development and validation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8624—Detection of slopes or peaks; baseline correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8827—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Monitoring And Testing Of Nuclear Reactors (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063123170P | 2020-12-09 | 2020-12-09 | |
| US63/123,170 | 2020-12-09 | ||
| PCT/IB2021/061322 WO2022123412A1 (en) | 2020-12-09 | 2021-12-03 | Mechanistic ion-exchange chromatography model calibration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2021397425A1 true AU2021397425A1 (en) | 2023-05-25 |
| AU2021397425A9 AU2021397425A9 (en) | 2024-10-24 |
Family
ID=78845067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021397425A Pending AU2021397425A1 (en) | 2020-12-09 | 2021-12-03 | Mechanistic ion-exchange chromatography model calibration |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250264445A1 (https=) |
| EP (1) | EP4260060B1 (https=) |
| JP (1) | JP7830467B2 (https=) |
| AU (1) | AU2021397425A1 (https=) |
| CA (1) | CA3198086A1 (https=) |
| MX (1) | MX2023006681A (https=) |
| WO (1) | WO2022123412A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230359888A1 (en) * | 2022-05-03 | 2023-11-09 | Accenture Global Solutions Limited | Optimization and digital twin of chromatography purification process using physics-informed neural networks |
| CN121057616A (zh) * | 2023-05-04 | 2025-12-02 | 环球生命科学解决方案德国有限公司 | 分离过程的跨规模工艺开发方法 |
-
2021
- 2021-12-03 AU AU2021397425A patent/AU2021397425A1/en active Pending
- 2021-12-03 EP EP21824052.1A patent/EP4260060B1/en active Active
- 2021-12-03 MX MX2023006681A patent/MX2023006681A/es unknown
- 2021-12-03 US US18/038,880 patent/US20250264445A1/en active Pending
- 2021-12-03 CA CA3198086A patent/CA3198086A1/en active Pending
- 2021-12-03 WO PCT/IB2021/061322 patent/WO2022123412A1/en not_active Ceased
- 2021-12-03 JP JP2023532725A patent/JP7830467B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3198086A1 (en) | 2022-06-16 |
| WO2022123412A1 (en) | 2022-06-16 |
| JP7830467B2 (ja) | 2026-03-16 |
| MX2023006681A (es) | 2023-06-22 |
| EP4260060A1 (en) | 2023-10-18 |
| JP2024501406A (ja) | 2024-01-12 |
| AU2021397425A9 (en) | 2024-10-24 |
| US20250264445A1 (en) | 2025-08-21 |
| EP4260060B1 (en) | 2026-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SREP | Specification republished |