MX2023002613A - Composiciones de matriquina derivada de tejidos y metodos para su realizacion. - Google Patents

Composiciones de matriquina derivada de tejidos y metodos para su realizacion.

Info

Publication number
MX2023002613A
MX2023002613A MX2023002613A MX2023002613A MX2023002613A MX 2023002613 A MX2023002613 A MX 2023002613A MX 2023002613 A MX2023002613 A MX 2023002613A MX 2023002613 A MX2023002613 A MX 2023002613A MX 2023002613 A MX2023002613 A MX 2023002613A
Authority
MX
Mexico
Prior art keywords
tissue
composition
derived
peptides
matrikine
Prior art date
Application number
MX2023002613A
Other languages
English (en)
Inventor
John D O'neill
Igal Germanguz
Evelyn Aranda
Jennifer Xiong
Natalia Kissel
Alexandra Nichols
Eddie Gadee
Richard Nguyen
Drew Daly
Andrea Nye
Original Assignee
Xylyx Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xylyx Bio Inc filed Critical Xylyx Bio Inc
Publication of MX2023002613A publication Critical patent/MX2023002613A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se divulga una composición para administración tópica en un epitelio. La composición comprende un matrisoma desarmado que incluye uno o más péptidos de fragmentación enzimática provenientes del tejido biológico. La composición comprende además uno o más excipientes farmacéutica o cosméticamente aceptados. El matrisoma desarmado puede ser fragmentado por degradación mediante una o mas enzimas para producir el uno o más péptidos. El uno o más péptidos pueden estar configurados para retener la capacidad de señalización celular, promoviendo de este modo uno o más de regeneración tisular, reparación tisular, y homeostasis tisular. La composición puede utilizarse para tratar un tejido tal como tejido de la piel que presenta cicatrices, acné, eczema, psoriasis, y otras condiciones de la piel.
MX2023002613A 2020-09-08 2021-09-08 Composiciones de matriquina derivada de tejidos y metodos para su realizacion. MX2023002613A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063075638P 2020-09-08 2020-09-08
PCT/US2021/049432 WO2022055974A1 (en) 2020-09-08 2021-09-08 Tissue-derived matrikine compositions and methods therefor

Publications (1)

Publication Number Publication Date
MX2023002613A true MX2023002613A (es) 2023-03-27

Family

ID=78135106

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002613A MX2023002613A (es) 2020-09-08 2021-09-08 Composiciones de matriquina derivada de tejidos y metodos para su realizacion.

Country Status (10)

Country Link
US (1) US20240024431A1 (es)
EP (1) EP4210675A1 (es)
JP (1) JP2023547984A (es)
KR (1) KR20230065274A (es)
CN (1) CN116546971A (es)
AU (1) AU2021340630A1 (es)
CA (1) CA3191359A1 (es)
IL (1) IL301123A (es)
MX (1) MX2023002613A (es)
WO (1) WO2022055974A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023215764A2 (en) * 2022-05-03 2023-11-09 The Trustees Of Columbia University In The City Of New York Pathological remodeling of distal lung matrix in end-stage cystic fibrosis patients
WO2024011235A1 (en) 2022-07-08 2024-01-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for improving wound healing
CN116970071B (zh) * 2023-09-22 2023-12-01 英特菲尔(成都)生物制品有限责任公司 一种具有抗衰活性的重组弹性蛋白及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070020220A1 (en) 2005-04-27 2007-01-25 Procter & Gamble Personal care compositions
CN105727372A (zh) * 2016-02-25 2016-07-06 烟台隽秀生物科技有限公司 一种温敏性宫腔修复凝胶及其制备方法

Also Published As

Publication number Publication date
JP2023547984A (ja) 2023-11-15
KR20230065274A (ko) 2023-05-11
WO2022055974A1 (en) 2022-03-17
US20240024431A1 (en) 2024-01-25
CA3191359A1 (en) 2022-03-17
EP4210675A1 (en) 2023-07-19
AU2021340630A1 (en) 2023-03-16
CN116546971A (zh) 2023-08-04
IL301123A (en) 2023-05-01

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