MX2023000033A - Arimoclomol para tratar la enfermedad de gaucher. - Google Patents

Arimoclomol para tratar la enfermedad de gaucher.

Info

Publication number
MX2023000033A
MX2023000033A MX2023000033A MX2023000033A MX2023000033A MX 2023000033 A MX2023000033 A MX 2023000033A MX 2023000033 A MX2023000033 A MX 2023000033A MX 2023000033 A MX2023000033 A MX 2023000033A MX 2023000033 A MX2023000033 A MX 2023000033A
Authority
MX
Mexico
Prior art keywords
arimoclomol
gaucher disease
treating gaucher
treating
carbox
Prior art date
Application number
MX2023000033A
Other languages
English (en)
Inventor
Thomas Kirkegaard Jensen
Linda Ingemann
Christine Í Dali
Hinsby Anders Mørkeberg
Cathrine Kolster Fog-Tønnesen
Original Assignee
Kempharm Denmark As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kempharm Denmark As filed Critical Kempharm Denmark As
Publication of MX2023000033A publication Critical patent/MX2023000033A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un ingrediente farmacéutico activo que se selecciona a partir de cloruro de N-[2-hidroxi-3-(1-piperidinil)-propoxi]-piridin-1-óxido-3-carboxi midoilo, sus estereoisómeros y las sales de adición de ácido del mismo; específicamente arimoclomol, para ser utilizado en métodos para tratar la enfermedad de Gaucher (GD).
MX2023000033A 2020-06-24 2021-06-24 Arimoclomol para tratar la enfermedad de gaucher. MX2023000033A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20182067 2020-06-24
PCT/EP2021/067366 WO2021260120A1 (en) 2020-06-24 2021-06-24 Arimoclomol for treating gaucher disease

Publications (1)

Publication Number Publication Date
MX2023000033A true MX2023000033A (es) 2023-04-10

Family

ID=71143584

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023000033A MX2023000033A (es) 2020-06-24 2021-06-24 Arimoclomol para tratar la enfermedad de gaucher.

Country Status (11)

Country Link
US (1) US20230226036A1 (es)
EP (1) EP4171559A1 (es)
JP (1) JP2023531750A (es)
KR (1) KR20230035586A (es)
CN (1) CN116075305A (es)
AU (1) AU2021295437A1 (es)
BR (1) BR112022026396A2 (es)
CA (1) CA3183559A1 (es)
IL (1) IL299250A (es)
MX (1) MX2023000033A (es)
WO (1) WO2021260120A1 (es)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222994B1 (hu) 1995-11-02 2004-01-28 BIOREX Kutató és Fejlesztő Rt. Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására
HUP9900475D0 (en) 1999-02-26 1999-04-28 Biorex Kutato Fejlesztoe Kft O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
HUP0001583A2 (hu) 2000-04-18 2002-11-28 BIOREX Kutató és Fejlesztő Rt. Egy piridin-1-oxid-származék és eljárás annak átalakítására gyógyászati hatású vegyületekké
CA2728363C (en) * 2008-06-26 2019-02-19 Orphazyme Aps Use of hsp70 as a regulator of enzymatic activity
WO2011017177A1 (en) * 2009-07-28 2011-02-10 Shire Human Genetic Therapies Compositions and methods for treating gaucher disease
KR20240028540A (ko) * 2014-09-15 2024-03-05 제브라 덴마크 에이/에스 아리모클로몰 제제
EP3782624A1 (en) * 2016-04-29 2021-02-24 Orphazyme A/S Arimoclomol for treating glucocerebrosidase associated disorders
KR102279347B1 (ko) * 2016-12-15 2021-07-21 한국생명공학연구원 피리딘계 화합물을 유효성분으로 함유하는 dyrk 관련 질환의 예방 또는 치료용 약학적 조성물

Also Published As

Publication number Publication date
CN116075305A (zh) 2023-05-05
EP4171559A1 (en) 2023-05-03
KR20230035586A (ko) 2023-03-14
IL299250A (en) 2023-02-01
AU2021295437A1 (en) 2023-02-02
WO2021260120A1 (en) 2021-12-30
CA3183559A1 (en) 2021-12-30
JP2023531750A (ja) 2023-07-25
BR112022026396A2 (pt) 2023-03-14
US20230226036A1 (en) 2023-07-20

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