MX2022012272A - Composiciones y metodos para determinar la calidad del acido nucleico. - Google Patents

Composiciones y metodos para determinar la calidad del acido nucleico.

Info

Publication number
MX2022012272A
MX2022012272A MX2022012272A MX2022012272A MX2022012272A MX 2022012272 A MX2022012272 A MX 2022012272A MX 2022012272 A MX2022012272 A MX 2022012272A MX 2022012272 A MX2022012272 A MX 2022012272A MX 2022012272 A MX2022012272 A MX 2022012272A
Authority
MX
Mexico
Prior art keywords
compositions
methods
nucleic acid
quality determination
acid quality
Prior art date
Application number
MX2022012272A
Other languages
English (en)
Inventor
John F Thompson
Original Assignee
Personal Genome Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Personal Genome Diagnostics Inc filed Critical Personal Genome Diagnostics Inc
Publication of MX2022012272A publication Critical patent/MX2022012272A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/151—Modifications characterised by repeat or repeated sequences, e.g. VNTR, microsatellite, concatemer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/204—Modifications characterised by specific length of the oligonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2549/00—Reactions characterised by the features used to influence the efficiency or specificity
    • C12Q2549/10—Reactions characterised by the features used to influence the efficiency or specificity the purpose being that of reducing false positive or false negative signals
    • C12Q2549/119—Reactions characterised by the features used to influence the efficiency or specificity the purpose being that of reducing false positive or false negative signals using nested primers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

En la presente se proporcionan composiciones y métodos para determinar la calidad de los ácidos nucleicos en una muestra que incluye un primer conjunto de cebadores y un segundo conjunto de cebadores. Además, se proporcionan composiciones y métodos para determinar la calidad del ácido nucleico en una muestra que incluye conjuntos de cebadores para la amplificación de secuencias repetitivas de ácido nucleico.
MX2022012272A 2020-03-31 2021-03-30 Composiciones y metodos para determinar la calidad del acido nucleico. MX2022012272A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063002785P 2020-03-31 2020-03-31
PCT/US2021/024962 WO2021202583A2 (en) 2020-03-31 2021-03-30 Compositions and methods for nucleic acid quality determination

Publications (1)

Publication Number Publication Date
MX2022012272A true MX2022012272A (es) 2023-02-23

Family

ID=77929548

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022012272A MX2022012272A (es) 2020-03-31 2021-03-30 Composiciones y metodos para determinar la calidad del acido nucleico.

Country Status (11)

Country Link
US (1) US20230138540A1 (es)
EP (1) EP4127227A4 (es)
JP (1) JP7805308B2 (es)
KR (1) KR20220160633A (es)
CN (1) CN116113711A (es)
AU (1) AU2021248806A1 (es)
BR (1) BR112022019785A2 (es)
CA (1) CA3176620A1 (es)
GB (1) GB2609118A (es)
MX (1) MX2022012272A (es)
WO (1) WO2021202583A2 (es)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2317939T3 (es) * 2000-09-15 2009-05-01 Ventana Medical Systems, Inc. Oligonucleotidos para marcar sondas oligonucleotidicas y proteinas.
EP2500440B1 (en) * 2002-12-20 2015-12-16 Celera Corporation Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
EP1613774A2 (en) * 2003-03-10 2006-01-11 Applera Corporation Genetic polymorphisms associated with stenosis, methods of detection and uses thereof
EP1598429A1 (en) * 2004-05-19 2005-11-23 Amplion Ltd. Detection of amplicon contamination during PCR exhibiting two different annealing temperatures
JP2010029068A (ja) 2008-07-25 2010-02-12 Canon Inc 内部標準ｄｎａの製造方法
US20130315886A1 (en) * 2009-08-05 2013-11-28 Salk Institute For Biological Studies Retroelements and mental disorders and methods of measuring l1 retrotransposition
EP3460074B1 (en) * 2010-02-05 2020-10-07 Quest Diagnostics Investments Incorporated Method to detect repeat sequence motifs in nucleic acid
EP2881465B1 (en) 2012-07-30 2018-07-04 Hitachi, Ltd. Tag-sequence-attached two-dimensional cdna library device, and gene expression analysis method and gene expression analysis apparatus each utilizing same
US9957557B2 (en) * 2012-08-13 2018-05-01 Life Genetics Lab, Llc Development of a highly sensitive quantification system for assessing DNA degradation and quality in forensic samples
ES2866044T3 (es) 2014-02-18 2021-10-19 Illumina Inc Métodos y composiciones para la elaboración de perfiles de ADN
WO2016109604A2 (en) * 2014-12-29 2016-07-07 InnoGenomics Technologies, LLC Multiplexed assay for quantitating and assessing integrity of cell-free dna in biological fluids for cancer diagnosis, prognosis, and surveillance
US11702697B2 (en) 2018-05-14 2023-07-18 Roche Sequencing Solutions, Inc. Quality testing of DNA samples

Also Published As

Publication number Publication date
WO2021202583A2 (en) 2021-10-07
JP7805308B2 (ja) 2026-01-23
WO2021202583A3 (en) 2021-11-25
US20230138540A1 (en) 2023-05-04
JP2023520871A (ja) 2023-05-22
GB2609118A (en) 2023-01-25
EP4127227A2 (en) 2023-02-08
EP4127227A4 (en) 2024-04-24
AU2021248806A1 (en) 2022-10-13
GB202214558D0 (en) 2022-11-16
BR112022019785A2 (pt) 2022-11-16
CA3176620A1 (en) 2021-10-07
CN116113711A (zh) 2023-05-12
KR20220160633A (ko) 2022-12-06

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